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Latest & greatest articles for urinary tract infection
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on urinary tract infection or other clinical topics then use Trip today.
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Response to antibiotics of women with symptoms of urinarytractinfection but negative dipstick urine test results: double blind randomised controlled trial. To assess the effectiveness of antibiotic treatment of women with symptoms of urinarytractinfection but negative urine dipstick testing.Prospective, double blind, randomised, placebo controlled trial.Primary care, among a randomly selected group of general practitioners in Christchurch, New Zealand.59 women aged 16-50 years presenting (...) with a history of dysuria and frequency in whom a dipstick test of midstream urine was negative for both nitrites and leucocytes. Participants with complicated urinarytractinfection were excluded.Trimethoprim 300 mg daily for three days or placebo.Self reported diary of symptoms for seven days, recording the presence or absence of individual symptoms each day, followed by a structured telephone questionnaire after seven days. The main clinical outcome was resolution of dysuria at three and seven days
Effect of a multifaceted intervention on number of antimicrobial prescriptions for suspected urinarytractinfections in residents of nursing homes: cluster randomised controlled trial. To assess whether a multifaceted intervention can reduce the number of prescriptions for antimicrobials for suspected urinarytractinfections in residents of nursing homes.Cluster randomised controlled trial.24 nursing homes in Ontario, Canada, and Idaho, United States.12 nursing homes allocated (...) to a multifaceted intervention and 12 allocated to usual care. Outcomes were measured in 4217 residents.Diagnostic and treatment algorithm for urinarytractinfections implemented at the nursing home level using a multifaceted approach--small group interactive sessions for nurses, videotapes, written material, outreach visits, and one on one interviews with physicians.Number of antimicrobials prescribed for suspected urinarytractinfections, total use of antimicrobials, admissions to hospital, and deaths.Fewer
Rapid tests and urine sampling techniques for the diagnosis of urinarytractinfection (UTI) in children under five years: a systematic review Rapid tests and urine sampling techniques for the diagnosis of urinarytractinfection (UTI) in children under five years: a systematic review Rapid tests and urine sampling techniques for the diagnosis of urinarytractinfection (UTI) in children under five years: a systematic review Whiting P, Westwood M, Watt I, Cooper J, Kleijnen J CRD summary (...) This review concluded that for the diagnosis of urinarytractinfection (UTI), dipstick negative for both leucocyte esterase and nitrite or negative microscopic analysis for pyuria of a clean voided urine, bag or nappy/pad specimen may be used to rule out UTI, and that combinations of positive tests could similarly be used to rule in UTI. These conclusions are likely to be reliable. Authors' objectives To determine the accuracy of rapid tests for detecting urinarytractinfection (UTI) in children under 5
Further investigation of confirmed urinarytractinfection (UTI) in children under five years: a systematic review Further investigation of confirmed urinarytractinfection (UTI) in children under five years: a systematic review Further investigation of confirmed urinarytractinfection (UTI) in children under five years: a systematic review Westwood M E, Whiting P F, Cooper J, Watt I S, Kleijnen J CRD summary This review concluded that there is no evidence to suggest that routine (...) investigation of children with confirmed urinarytractinfection (UTI) is effective, and that further research on the effectiveness of investigation of UTI is urgently required. These conclusions are likely to be reliable. Authors' objectives To determine the most effective approach to the further investigation of confirmed urinarytractinfection (UTI) in children under 5 years of age. Searching The authors searched 16 databases (including MEDLINE and EMBASE) from inception to between October 2002
Circumcision for the prevention of urinarytractinfection in boys: a systematic review of randomised trials and observational studies Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Antibiotics for preventing recurrent urinarytractinfection in non-pregnant women. Urinarytractinfection (UTI) is a common health care problem. Recurrent UTI (RUTI) in healthy non-pregnant women is defined as three or more episodes of UTI during a twelve month period. Long-term antibiotics have been proposed as a prevention strategy for RUTI.To determine the efficacy (during and after) and safety of prophylactic antibiotics used to prevent uncomplicated RUTI in adult non-pregnant women.We
Diagnosing urinarytractinfection (UTI) in the under fives Diagnosing urinarytractinfection (UTI) in the under fives Diagnosing urinarytractinfection (UTI) in the under fives Centre for Reviews and Dissemination Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Centre for Reviews and Dissemination. Diagnosing urinarytractinfection (...) (UTI) in the under fives. University of York. Effective Health Care 8(6). 2004 Authors' objectives This Effective Health Care bulletin summarises the research evidence on the diagnosis of urinarytractinfection (UTI) in children under five years of age. Authors' conclusions Urinarytractinfection (UTI) is common in children under five. Children who are misdiagnosed can either fail to receive appropriate treatment or receive unnecessary treatment and investigation. All of the tests commonly used
Dipstick urinalysis for screening of childhood urinarytractinfection Dipstick urinalysis for screening of childhood urinarytractinfection Dipstick urinalysis for screening of childhood urinarytractinfection Turner T Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Turner T. Dipstick urinalysis for screening of childhood urinarytractinfection. Clayton (...) , Victoria: Centre for Clinical Effectiveness (CCE) 2003: 22 Authors' objectives This aim of this critical appraisal was to assess whether dipstick urinalysis is an appropriate method of screening for urinarytractinfection in children. Project page URL Indexing Status Subject indexing assigned by CRD MeSH Child; Urinalysis; UrinaryTractInfections /diagnosis Language Published English Country of organisation Australia Address for correspondence Monash Institute of Health Services Research, Block E
Imaging studies after a first febrile urinarytractinfection in young children. Guidelines from the American Academy of Pediatrics recommend obtaining a voiding cystourethrogram and a renal ultrasonogram for young children after a first urinarytractinfection; renal scanning with technetium-99m-labeled dimercaptosuccinic acid has also been endorsed by other authorities. We investigated whether imaging studies altered management or improved outcomes in young children with a first febrile (...) only if antimicrobial prophylaxis is effective in reducing reinfections and renal scarring. Renal scans obtained at presentation identify children with acute pyelonephritis, and scans obtained six months later identify those with renal scarring. The routine performance of urinalysis, urine culture, or both during subsequent febrile illnesses in all children with a previous febrile urinarytractinfection will probably obviate the need to obtain either early or late scans.Copyright 2003
A nurse led education and direct access service for the management of urinarytractinfections in children: prospective controlled trial. To determine whether a nurse led education and direct access service improves the care of children with urinarytract infections.Prospective cluster randomised trial.General practitioners in the catchment area of a UK paediatric nephrology department.88 general practices (346 general practitioners, 107 000 children).Rate and quality of diagnosis of urinary (...) tractinfection, use of prophylactic antibiotics, convenience for families, and the number of infants with vesicoureteric reflux in whom renal scarring may have been prevented.The study practices diagnosed twice as many urinarytractinfections as the control practices (6.42 v 3.45/1000 children/year; ratio 1.86, 95% confidence interval 1.42 to 2.44); nearly four times more in infants (age < 1 year) and six times more in children without specific symptoms. Diagnoses were made more robustly by study
Ultrasonography and abdominal radiography versus intravenous urography in investigation of urinarytractinfection in men: prospective incident cohort study. To compare ultrasonography and abdominal radiography with intravenous urography in the investigation of urinarytractinfection in men.Prospective study in two hospital departments. Radiological procedures and urological assessments performed on different days by different cliniciansDistrict general hospital.Consecutive series of men (n (...) emptying bladder (34). The combination of plain radiographs of kidneys, ureter, and bladder and ultrasonography detected more abnormalities than intravenous urography alone. No important abnormality was missed by this combination (sensitivity 100% and specificity 93%).Ultrasonography with abdominal radiography is as accurate as intravenous urography in detecting important urological abnormalities in men presenting with urinarytractinfection. This combination is safer than intravenous urography
Methenamine hippurate for preventing urinarytractinfections. Methenamine salts are often used for the prevention of urinarytractinfection (UTI).To assess the effectiveness of methenamine hippurate in preventing UTI.Published and unpublished randomised controlled trials were identified from the Cochrane Controlled Trials Register, MEDLINE, EMBASE, CINAHL, Current Contents, reference lists of review articles and retrieved trials. The manufacturers' of methenamine salts were contacted (...) methenamine hippurate. Interpretation of the pooled estimates was not done in view of underlying heterogeneity. The study by Pettersson 1989 explained some, but not all, of the underlying heterogeneity. This study differed from all others by including patients with known upper renal tract abnormalities. Adverse reactions were mentioned by 10 studies. The rate of adverse events was low.There is not enough evidence to conclusively support the use of methenamine hippurate for urinary prophylaxis
A meta-analysis of randomized, controlled trials comparing short- and long-course antibiotic therapy for urinarytractinfections in children A meta-analysis of randomized, controlled trials comparing short- and long-course antibiotic therapy for urinarytractinfections in children A meta-analysis of randomized, controlled trials comparing short- and long-course antibiotic therapy for urinarytractinfections in children Keren R, Chan E Authors' objectives To determine whether long-course (...) antibiotic therapy is more effective than short-course therapy for the treatment of urinarytractinfections (UTIs) in children, and to explore potential sources of heterogeneity in the results of existing studies. Searching MEDLINE was searched for all studies published in the English language that compared short- and long-course therapy for the treatment of acute UTI in children. The searches were indexed by the MeSH terms 'urinarytractinfection' and 'antibiotics', and were limited to RCTs, children
of rapid dipstick tests, such as leucocyte esterase and nitrite, in the diagnosis of UTI in children should be performed. Bibliographic details Huicho L, Campos-Sanchez M, Alamo C. Metaanalysis of urine screening tests for determining the risk of urinarytractinfection in children. Pediatric Infectious Disease Journal 2002; 21(1): 1-11 PubMedID Other publications of related interest 1. Mulrow CD, Linn WD, Gaul MK, Pugh JA. Assessing quality of a diagnostic test evaluation. J Gen Intern Med 1989;4:288 (...) Metaanalysis of urine screening tests for determining the risk of urinarytractinfection in children Metaanalysis of urine screening tests for determining the risk of urinarytractinfection in children Metaanalysis of urine screening tests for determining the risk of urinarytractinfection in children Huicho L, Campos-Sanchez M, Alamo C Authors' objectives To summarise the literature and perform a meta-analysis of studies on urine screening tests for urinarytractinfection (UTI) in children
Antimicrobial prophylaxis for urinarytractinfection in persons with spinal cord dysfunction Antimicrobial prophylaxis for urinarytractinfection in persons with spinal cord dysfunction Antimicrobial prophylaxis for urinarytractinfection in persons with spinal cord dysfunction Morton S C, Shekelle P G, Adams J L, Bennett C, Dobkin B H, Montgomerie J, Vickrey B G Authors' objectives To assess the benefits and harms of antimicrobial prophylaxis to prevent urinarytractinfections (UTIs (...) ) in persons with neurogenic bladders caused by spinal cord dysfunction. Searching MEDLINE from 1966 to January 1998, and EMBASE from 1974 to January 1998, were searched using the following search terms: 'urinarytract', 'urinarytractinfections', 'bacteriuria', 'paraplegia', 'quadriplegia', 'spinal cord injuries', 'multiple sclerosis', 'neurogenic bladder' and 'neuropathic bladder' (free text term). Case reports and studies of animals were excluded. CINAHL was also searched from 1982 to July 1998 using
A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinarytractinfection in women A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinarytractinfection in women A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinarytractinfection in women Stothers L Record (...) Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study examined two different ways of giving cranberry to women who had suffered from urinarytractinfection in the preceding calendar year. One was juice based (250ml of pure unsweetened
Does this woman have an acute uncomplicated urinarytractinfection? Does this woman have an acute uncomplicated urinarytractinfection? Does this woman have an acute uncomplicated urinarytractinfection? Bent S, Nallamothu B K, Simel D L, Fihn S D, Saint S Authors' objectives To review the accuracy and precision of history taking and physical examination for the diagnosis of urinarytractinfection (UTI) in women. Searching MEDLINE was searched from 1966 to September 2001 using search terms (...) such as 'urinarytractinfection', 'diagnostic tests', 'physical examination', 'sensitivity' and 'specificity'. The complete search strategy is available from the authors on request. The references list of the identified articles were also examined. Further material was obtained by searching articles used to develop a recent guideline for treating acute uncomplicated UTI in women, and three commonly used clinical skills textbooks, and by contacting experts in the field. Study selection Study designs
Cluster randomised controlled trial of tailored interventions to improve the management of urinarytractinfections in women and sore throat. To assess the effectiveness of tailored interventions to implement guidelines for urinarytractinfections in women and sore throat.Unblinded, cluster randomised pretest-post-test trial.142 general practices in Norway.72 practices received interventions to implement guidelines for urinarytractinfection and 70 practices received interventions (...) to implement guidelines for sore throat, serving as controls for each other. 59 practices in the urinarytractinfection group and 61 practices in the sore throat group completed the study. Outcomes were measured in 16 939 consultations for sore throat and 9887 consultations for urinarytract infection.Interventions were developed to overcome identified barriers to implementing the guidelines. The main components of the tailored interventions were patient educational material, computer based decision
Does this woman have an acute uncomplicated urinarytractinfection? Symptoms suggestive of acute urinarytractinfection (UTI) constitute one of the most common reasons for women to visit clinicians. Although the clinical encounter typically involves taking a history and performing a physical examination, the diagnostic accuracy of the clinical assessment for UTI remains uncertain.To review the accuracy and precision of history taking and physical examination for the diagnosis of UTI (...) decreased the likelihood of UTI when present (LRs, 0.3 and 0.2, respectively). One study examined combinations of symptoms, and the resulting LRs were more powerful (24.6 for the combination of dysuria and frequency but no vaginal discharge or irritation). One study of patients with recurrent UTI found that self-diagnosis significantly increased the probability of UTI (LR, 4.0).In women who present with 1 or more symptoms of UTI, the probability of infection is approximately 50%. Specific combinations
Widespread distribution of urinarytractinfections caused by a multidrug-resistant Escherichia coli clonal group. The management of urinarytractinfections is complicated by the increasing prevalence of antibiotic-resistant strains of Escherichia coli. We studied the clonal composition of E. coli isolates that were resistant to trimethoprim-sulfamethoxazole from women with community-acquired urinarytract infections.Prospectively collected E. coli isolates from women with urinarytract (...) A. Most of the clonal group A isolates were serotype O11:H(nt) or O77:H(nt), with similar patterns of virulence factors, antibiotic susceptibility, and electrophoretic features.In three geographically diverse communities, a single clonal group accounted for nearly half of community-acquired urinarytractinfections in women that were caused by E. coli strains with resistance to trimethoprim-sulfamethoxazole. The widespread distribution and high prevalence of E. coli clonal group A has major public