Latest & greatest articles for type 2 diabetes

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Top results for type 2 diabetes

61. Insulin glargine/lixisenatide (type 2 diabetes mellitus) - Benefit assessment according to §35a Social Code Book V

: November 2014 [online]. 11.2014 [Accessed: 11.03.2020]. URL: http://www.deutsche- diabetes-gesellschaft.de/fileadmin/Redakteur/Leitlinien/Evidenzbasierte_Leitlinien/dm- therapie-1aufl-vers4-lang.pdf. The full report (German version) is published under https://www.iqwig.de/en/projects-results/projects/drug-assessment/a20-38-insulin-glargine- lixisenatide-type-2-diabetes-mellitus-benefit-assessment-according-to-35a-social-code-book- v.13098.html. (...) Insulin glargine/lixisenatide (type 2 diabetes mellitus) - Benefit assessment according to §35a Social Code Book V 1 Translation of Sections 2.1 to 2.5 of the dossier assessment Insulin glargin/Lixisenatid (Diabetes mellitus Typ 2) – Nutzenbewertung gemäß § 35a SGB V (Version 1.0; Status: 13 July 2020). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely

2020 Institute for Quality and Efficiency in Healthcare (IQWiG)

62. Patient-reported outcomes in a study of human regular U-500 insulin delivered by continuous subcutaneous insulin infusion or multiple daily injections in patients with type 2 diabetes Full Text available with Trip Pro

(12):2496-2501. Bode BW. Insulin pump use in type 2 diabetes. Diabetes Technol Ther. 2010;12(Suppl 1):S17-S21. Grunberger G, Bhargava A, Ly T, et al. Human regular U-500 insulin via continuous subcutaneous insulin infusion versus multiple daily injections in adults with type 2 diabetes: the VIVID study. Diabetes Obes Metab. 2020;22(3):434-441. Brod M, Hammer M, Christensen T, Lessard S, Bushnell DM. Understanding and assessing the impact of treatment in diabetes: the treatment-related impact (...) Patient-reported outcomes in a study of human regular U-500 insulin delivered by continuous subcutaneous insulin infusion or multiple daily injections in patients with type 2 diabetes Patient-reported outcomes in a study of human regular U-500 insulin delivered by continuous subcutaneous insulin infusion or multiple daily injections in patients with type 2 diabetes - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard

2020 EvidenceUpdates

63. Lower cardiorenal risk with sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study Full Text available with Trip Pro

Lower cardiorenal risk with sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study Lower cardiorenal risk with sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study - PubMed This site needs JavaScript (...) RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Diabetes Obes Metab Actions . 2020 Sep 7. doi: 10.1111/dom.14189. Online ahead of print. Lower cardiorenal risk with sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Oslo

2020 EvidenceUpdates

64. Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies Full Text available with Trip Pro

Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced (...) Actions . 2020 Nov;43(11):2713-2720. doi: 10.2337/dc20-0924. Epub 2020 Sep 14. Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies , , , , , , , , , , Affiliations Expand Affiliations 1 Keck School of Medicine of the University of Southern California, Los Angeles, CA annepete@med.usc.edu. 2 University of Texas Southwestern Medical Center at Dallas, Dallas, TX. 3 Kinder Krakenhaus auf der Bult

2020 EvidenceUpdates

65. Effect of Peer Mentors in Diabetes Self-management vs Usual Care on Outcomes in US Veterans With Type 2 Diabetes: A Randomized Clinical Trial Full Text available with Trip Pro

Effect of Peer Mentors in Diabetes Self-management vs Usual Care on Outcomes in US Veterans With Type 2 Diabetes: A Randomized Clinical Trial Effect of Peer Mentors in Diabetes Self-management vs Usual Care on Outcomes in US Veterans With Type 2 Diabetes: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable (...) : 10.1001/jamanetworkopen.2020.16369. Effect of Peer Mentors in Diabetes Self-management vs Usual Care on Outcomes in US Veterans With Type 2 Diabetes: A Randomized Clinical Trial , , , , , Affiliations Expand Affiliations 1 Corporal Michael J. Crescenz VA Medical Center, VA Center for Health Equity Research and Promotion, Philadelphia, Pennsylvania. 2 Division of General Internal Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia. 3 Division of Addiction Medicine and Urban

2020 EvidenceUpdates

66. Efficacy and safety of polyethylene glycol loxenatide (PEX168) monotherapy in type 2 diabetes patients: a multicenter, randomized, double-blind, placebo-controlled, phase 3a clinical trial. Full Text available with Trip Pro

Efficacy and safety of polyethylene glycol loxenatide (PEX168) monotherapy in type 2 diabetes patients: a multicenter, randomized, double-blind, placebo-controlled, phase 3a clinical trial. Efficacy and safety of polyethylene glycol loxenatide monotherapy in type 2 diabetes patients: A multicentre, randomized, double-blind, placebo-controlled phase 3a clinical trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features (...) Share Permalink Copy Page navigation Diabetes Obes Metab Actions . 2020 Sep 23. doi: 10.1111/dom.14198. Online ahead of print. Efficacy and safety of polyethylene glycol loxenatide monotherapy in type 2 diabetes patients: A multicentre, randomized, double-blind, placebo-controlled phase 3a clinical trial , , , , , , , , , , , Affiliations Expand Affiliations 1 China-Japan Friendship Hospital, Beijing, China. 2 Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University

2020 EvidenceUpdates

67. Efficacy and safety of ertugliflozin in older patients with type 2 diabetes: A pooled analysis of phase III studies Full Text available with Trip Pro

Efficacy and safety of ertugliflozin in older patients with type 2 diabetes: A pooled analysis of phase III studies Efficacy and safety of ertugliflozin in older patients with type 2 diabetes: A pooled analysis of phase III studies - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation (...) of ertugliflozin in older patients with type 2 diabetes: A pooled analysis of phase III studies , , , , , , , , , , , Affiliations Expand Affiliations 1 AdventHealth Translational Research Institute for Metabolism and Diabetes, Orlando, Florida, USA. 2 University of Tennessee Health Science Center, Memphis, Tennessee, USA. 3 University of Nantes, Nantes, France. 4 Merck & Co., Inc., Kenilworth, New Jersey, USA. 5 Pfizer Inc., Groton, Connecticut, USA. 6 Pfizer Inc., New York, New York, USA. 7 Pfizer Inc

2020 EvidenceUpdates

68. Comprehensive Type 2 Diabetes Management Algorithm

Comprehensive Type 2 Diabetes Management Algorithm ENDOCRINE PRACTICE Vol 26 No. 1 January 2020 107 CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM – 2020 EXECUTIVE SUMMARY Alan J. Garber, MD, PhD, MACE 1 ; Yehuda Handelsman, MD, FACP , FNLA, MACE 2 ; George Grunberger, MD, FACP , FACE 3 ; Daniel Einhorn, MD, FACP , FACE 4 ; Martin J. Abrahamson, MD 5 ; Joshua I. Barzilay (...) trial; SU = sulfonylurea; SGLT2 = sodium-glucose cotransporter 2; SMBG = self-moni- toring of blood glucose; T2D = type 2 diabetes; TZD = thiazolidinedione EXECUTIVE SUMMARY This algorithm for the comprehensive management of persons with type 2 diabetes (T2D) was developed to provide clinicians with a practical guide that considers the whole patient, his or her spectrum of risks and complica- tions, and evidence-based approaches to treatment. It is now clear that the progressive pancreatic beta-cell

2020 American Association of Clinical Endocrinologists

69. An Early-Onset Subgroup of Type 2 Diabetes: A Multigenerational, Prospective Analysis in the Framingham Heart Study

An Early-Onset Subgroup of Type 2 Diabetes: A Multigenerational, Prospective Analysis in the Framingham Heart Study An Early-Onset Subgroup of Type 2 Diabetes: A Multigenerational, Prospective Analysis in the Framingham Heart Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation (...) Subgroup of Type 2 Diabetes: A Multigenerational, Prospective Analysis in the Framingham Heart Study , , , , , , , Affiliations Expand Affiliations 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Johns Hopkins University, Baltimore, MD jechouf1@jhmi.edu. 2 Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland. 3 Department of Biostatistics, Boston University School of Public Health, Boston, MA. 4 Division of Cardiovascular Medicine

2020 EvidenceUpdates

70. The impact of pharmacological and lifestyle interventions on body weight in people with type 1 diabetes: A systematic review and meta-analysis Full Text available with Trip Pro

/dom.14221. Online ahead of print. The impact of pharmacological and lifestyle interventions on body weight in people with type 1 diabetes: A systematic review and meta-analysis , , , , Affiliations Expand Affiliations 1 School of Population Health and Environmental Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK. 2 Institute of Diabetes Endocrinology and Obesity, King's Health Partners, London, UK. 3 Diabetes Research Group, Weston Education Centre, King's (...) : Item in Clipboard Full-text links Cite Display options Display options Format Abstract Aim: To systematically review the effects of pharmacological and lifestyle interventions on body weight as a secondary outcome in people with type 1 diabetes. Methods: The Ovid Medline, Embase and Cochrane Library databases were searched for relevant pharmacological (glucagon-like peptide-1 [GLP-1] receptor agonist, sodium-glucose co-transporter-2 [SGLT-2] inhibitor, dipeptidyl peptidase-4 [DPP-4] inhibitor

2020 EvidenceUpdates

71. Cardiovascular events and mortality in people with type 2 diabetes and multimorbidity: A real-world study of patients followed for up to 19 years Full Text available with Trip Pro

Cardiovascular events and mortality in people with type 2 diabetes and multimorbidity: A real-world study of patients followed for up to 19 years Cardiovascular events and mortality in people with type 2 diabetes and multimorbidity: A real-world study of patients followed for up to 19 years - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily (...) : 10.1111/dom.14218. Online ahead of print. Cardiovascular events and mortality in people with type 2 diabetes and multimorbidity: A real-world study of patients followed for up to 19 years , , , , Affiliations Expand Affiliations 1 Leicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, UK. 2 Novo Nordisk Region Europe Pharmaceuticals A/S, København, Denmark. 3 Department of Diabetes Medicine, National Institute for Health Research

2020 EvidenceUpdates

72. Gastrointestinal adverse events with insulin glargine/lixisenatide fixed-ratio combination versus glucagon-like peptide-1 receptor agonists in people with type 2 diabetes mellitus: A network meta-analysis Full Text available with Trip Pro

Gastrointestinal adverse events with insulin glargine/lixisenatide fixed-ratio combination versus glucagon-like peptide-1 receptor agonists in people with type 2 diabetes mellitus: A network meta-analysis Gastrointestinal adverse events with insulin glargine/lixisenatide fixed-ratio combination versus glucagon-like peptide-1 receptor agonists in people with type 2 diabetes mellitus: A network meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage (...) Display options Format Share Permalink Copy Page navigation Diabetes Obes Metab Actions . 2020 Sep 29. doi: 10.1111/dom.14202. Online ahead of print. Gastrointestinal adverse events with insulin glargine/lixisenatide fixed-ratio combination versus glucagon-like peptide-1 receptor agonists in people with type 2 diabetes mellitus: A network meta-analysis , , , , , , , Affiliations Expand Affiliations 1 Centre of Research Excellence in Translating Nutritional Science to Good Health, University

2020 EvidenceUpdates

73. Renal and Cardiovascular Effects of SGLT2 Inhibition in Combination with Loop Diuretics in Patients with Type 2 Diabetes and Chronic Heart Failure: The RECEDE-CHF Trial Full Text available with Trip Pro

Renal and Cardiovascular Effects of SGLT2 Inhibition in Combination with Loop Diuretics in Patients with Type 2 Diabetes and Chronic Heart Failure: The RECEDE-CHF Trial Renal and Cardiovascular Effects of SGLT2 Inhibition in Combination With Loop Diuretics in Patients With Type 2 Diabetes and Chronic Heart Failure: The RECEDE-CHF Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several (...) Circulation Actions . 2020 Nov 3;142(18):1713-1724. doi: 10.1161/CIRCULATIONAHA.120.048739. Epub 2020 Aug 29. Renal and Cardiovascular Effects of SGLT2 Inhibition in Combination With Loop Diuretics in Patients With Type 2 Diabetes and Chronic Heart Failure: The RECEDE-CHF Trial # , # , , , , Affiliations Expand Affiliations 1 Division of Molecular and Clinical Medicine, University of Dundee, Scotland, United Kingdom (N.A.M., I.R.M., R.J.M., A.D.S., C.C.L.). 2 Royal Infirmary of Edinburgh, Scotland, United

2020 EvidenceUpdates

74. Sodium-glucose co-transporter-2 inhibition and ocular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis

Sodium-glucose co-transporter-2 inhibition and ocular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis Sodium-glucose co-transporter-2 inhibition and ocular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 (...) . Online ahead of print. Sodium-glucose co-transporter-2 inhibition and ocular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Cardiovascular Centre, Beijing Tongren Hospital, Capital Medical University, Beijing, China. 2 George Institute for Global Health, UNSW Sydney, Sydney, Australia. 3 Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 4

2020 EvidenceUpdates

75. Dapagliflozin (Forxiga): no place in type 1 diabetes

Dapagliflozin (Forxiga°) has no demonstrated efficacy with regard to the clinical complications of type 1 diabetes and it carries a risk of sometimes serious adverse effects. Dapagliflozin is one of the gliflozin group of hypoglycaemic drugs, which lower blood glucose levels by increasing excretion of glucose in the urine. In the European Union, the glifozins were first authorised for patients with type 2 diabetes. In that setting, their harm-benefit balance is unfavourable, mainly due to the risk (...) : "Dapagliflozin in type 2 diabetes: no advance in terms of cardiovascular complications" (January 2020) "Gliflozins: necrotising fasciitis of the perineum" Prescrire Int 2019; 28 (206): 181 "Empagliflozin (Jardiance°) in type 2 diabetes: no rush to use this drug" (June 2016) "Gliflozins: ketoacidosis" Prescrire Int 2016; 25 (169): 68 "Dapagliflozin. A hypoglycaemic drug causing disproportionate harm, especially to kidneys" Prescrire Int 2014; 23 (147): 61-64. Read more: All the subjects in Prescrire's

2020 Prescrire

76. A duodenal sleeve bypass device added to intensive medical therapy for obesity with type 2 diabetes: a RCT Full Text available with Trip Pro

A duodenal sleeve bypass device added to intensive medical therapy for obesity with type 2 diabetes: a RCT A duodenal sleeve bypass device added to intensive medical therapy for obesity with type 2 diabetes: a RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need (...) , Ghadah Aldubaikhi 4 , Ben Glover 1 , Joanne Lord 6 , Olu Onyimadu 6 , Emmanuela Falaschetti 5 , Natalia Klimowska-Nassar 5 , Hutan Ashrafian 1 , James Byrne 7 , Julian P Teare 1 1 Department of Surgery and Cancer, St Mary’s Hospital, Imperial College London, London, UK 2 National Institute for Health Research Southampton Biomedical Research Centre, Southampton Centre for Biomedical Research, Southampton General Hospital, Southampton, UK 3 Section of Investigative Medicine, Division of Diabetes

2020 NIHR HTA programme

77. Continuous glucose monitoring in pregnant women with type 1 diabetes

for NHSScotland. Epidemiology and predicted volume According to Diabetes UK, 5% of the 956,861 pregnancies in the UK in 2015 involved diabetes: ? 42,000 involved gestational diabetes (87.5%) ? 3,600 involved T1DM (7.5%) ? 2,400 involved type 2 diabetes (5%) 2 The number of women in Scotland with T1DM who became pregnant rose from 205 in 1998/99 to 264 in 2012/13 3 . Scottish context The Scottish Intercollegiate Guidelines Network (SIGN) guideline on The Management of Diabetes (published in 2010 and updated (...) in 2017 with the section on pregnancy currently being reviewed) includes a recommendation that: “Continuous glucose monitoring may be considered in women with type 1 and type 2 diabetes.” In June 2017, the Scottish Government wrote to Health Boards announcing £10m funding over 5 years to increase insulin pump use and encourage the implementation of CGM systems 4 . In a Scottish Government letter dated July 2019, those considered highest priority for commencement of CGM included pregnant women

2020 SHTG Advice Statements

78. Cardiovascular Outcomes with Ertugliflozin in Type 2 Diabetes. Full Text available with Trip Pro

Cardiovascular Outcomes with Ertugliflozin in Type 2 Diabetes. The cardiovascular effects of ertugliflozin, an inhibitor of sodium-glucose cotransporter 2, have not been established.In a multicenter, double-blind trial, we randomly assigned patients with type 2 diabetes and atherosclerotic cardiovascular disease to receive 5 mg or 15 mg of ertugliflozin or placebo once daily. With the data from the two ertugliflozin dose groups pooled for analysis, the primary objective was to show (...) -mg dose of ertugliflozin and in 57 patients (2.1%) who received the 15-mg dose, as compared with 45 patients (1.6%) who received placebo.Among patients with type 2 diabetes and atherosclerotic cardiovascular disease, ertugliflozin was noninferior to placebo with respect to major adverse cardiovascular events. (Funded by Merck Sharp & Dohme and Pfizer; VERTIS CV ClinicalTrials.gov number, NCT01986881.).Copyright © 2020 Massachusetts Medical Society.

2020 NEJM

79. Early combination therapy delayed treatment escalation in newly diagnosed young-onset type 2 diabetes: A subanalysis of the VERIFY study

Early combination therapy delayed treatment escalation in newly diagnosed young-onset type 2 diabetes: A subanalysis of the VERIFY study Early combination therapy delayed treatment escalation in newly diagnosed young-onset type 2 diabetes: A subanalysis of the VERIFY study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 (...) combination therapy delayed treatment escalation in newly diagnosed young-onset type 2 diabetes: A subanalysis of the VERIFY study , , , , , Affiliations Expand Affiliations 1 Department of Medicine & Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China. 2 Children's Hospital, Helsinki University and Helsinki University Hospital, Helsinki, Finland. 3 Research Program

2020 EvidenceUpdates

80. Efficacy and safety of polyethylene glycol loxenatide as add-on to metformin in patients with type 2 diabetes: A multicentre, randomized, double-blind, placebo-controlled, phase 3b trial Full Text available with Trip Pro

Efficacy and safety of polyethylene glycol loxenatide as add-on to metformin in patients with type 2 diabetes: A multicentre, randomized, double-blind, placebo-controlled, phase 3b trial Efficacy and safety of polyethylene glycol loxenatide as add-on to metformin in patients with type 2 diabetes: A multicentre, randomized, double-blind, placebo-controlled, phase 3b trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features (...) navigation Diabetes Obes Metab Actions . 2020 Aug 3. doi: 10.1111/dom.14163. Online ahead of print. Efficacy and safety of polyethylene glycol loxenatide as add-on to metformin in patients with type 2 diabetes: A multicentre, randomized, double-blind, placebo-controlled, phase 3b trial , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes

2020 EvidenceUpdates