Latest & greatest articles for stroke

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Top results for stroke

1. Additional, Mechanized Upper Limb Self-Rehabilitation in Patients With Subacute Stroke: The REM-AVC Randomized Trial

Additional, Mechanized Upper Limb Self-Rehabilitation in Patients With Subacute Stroke: The REM-AVC Randomized Trial Additional, Mechanized Upper Limb Self-Rehabilitation in Patients With Subacute Stroke: The REM-AVC Randomized Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 Information Show account info Close (...) RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Stroke Actions . 2021 Jun;52(6):1938-1947. doi: 10.1161/STROKEAHA.120.032545. Epub 2021 Apr 29. Additional, Mechanized Upper Limb Self-Rehabilitation in Patients With Subacute Stroke: The REM-AVC Randomized Trial , , , , , , , Collaborators, Affiliations Expand Collaborators REM Investigative Team* : , , , , , , , , , , , , , , , , , , Affiliations 1 Physical and Rehabilitation

2021 EvidenceUpdates

2. Early dual antiplatelet therapy after minor stroke: Does it take two to tango?

Early dual antiplatelet therapy after minor stroke: Does it take two to tango? TOOLS FOR PRACTICE #291 | May 31, 2021 Early dual antiplatelet therapy after minor stroke: Does it take two to tango? CLINICAL QUESTION In acute non-cardioembolic minor ischemic stroke or transient ischemic attack (TIA), does adding a second antiplatelet (like clopidogrel or ticagrelor) to ASA reduce recurrent stroke? BOTTOM LINE Compared to ASA alone, clopidogrel plus ASA reduced the risk of stroke from 8.2% to 5.5 (...) TIA versus ASA alone for 21-90 days, followed by single antiplatelet. o At 21 days: ? Ischemic stroke: 5.5% versus 8.2% (ASA), number needed to treat (NNT)=38. ? Major bleed: 1.2% versus 0.6% (ASA) (number needed to harm [NNH]=167) o On days 22-90: 1,2 ? Ischemic stroke: No difference. ? Major bleed: 0.6% versus 0.3% (ASA), NNH=334. • Ticagrelor + ASA versus ASA: One RCT, 11,016 patients: 3 o Started ticagrelor (180mg on day 1, then 90mg twice daily) plus ASA within 24 hours of mild-moderate

2021 Tools for Practice

3. Detection of paroxysmal atrial fibrillation in patients with newly diagnosed ischaemic stroke

vessels or by emboli from a proximal arterial source or the heart. 1 Transient Ischaemic Attack (TIA): A neurological deficit lasting less than 24 hours, caused by cerebral ischaemia. 1 Literature search A systematic search of the primary and secondary literature was carried out between 26 August and 8 September 2020 to identify systematic reviews, health technology assessments and other evidence based reports. The Medline and Embase databases were searched for systematic reviews, meta-analyses (...) diagnosed ischaemic stroke who are selected to have prolonged electrocardiogram (ECG) monitoring. Why is this important? There is variation across NHSScotland in provision of prolonged ECG monitoring for patients with ischaemic stroke. Some NHS boards refer all patients with ischaemic stroke/transient ischaemic attack (TIA) for prolonged monitoring, whilst other boards refer very few patients. The decision to refer patients is partly dependent on access to monitoring, and there is variation across

2021 SHTG Advice Statements

4. RapidAI for analysing CT/MRI brain scans in people with suspected acute stroke

. • APRIL: Clinical Study of ApTOLL for the Treatment of Acute Ischemic Stroke. ClinicalTrials.gov Identifier: NCT04734548. Status: recruiting. Indication: acute ischaemic stroke. Treatments: ApT oll compared with placebo. Country: Spain. • ANGEL -ASPECT: Study of Endovascular Therapy in Acute Anterior Circulation Large Vessel Occlusive Patients With a Large Infarct Core. ClinicalTrials.gov Identifier: NCT04551664. Status: recruiting. Indication: acute ischaemic stroke. Treatments: endovascular (...) onset to endovascular reperfusion and from qualifying imaging to endovascular reperfusion are strongly associated with increased likelihood of functional independence and decreased disability in people with stroke (Goyal et al. 2016 and Sheth et al. 2015). Current care pathway Current care pathway For people admitted with suspected stroke, NICE's guideline on stroke and transient ischaemic attack in over 16s: diagnosis and initial management recommends the prompt use of FAST (face arm speech test

2021 National Institute for Health and Clinical Excellence - Advice

5. P2Y12 Inhibitors Plus Aspirin Versus Aspirin Alone in Patients With Minor Stroke or High-Risk Transient Ischemic Attack

Institute, Duke University, Durham, NC (Y. Xian). 7 Dell Medical School, University of Texas, Austin (S.C.J.). 8 Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Y.-J.W.). # Contributed equally. PMID: 34039032 DOI: Item in Clipboard P2Y12 Inhibitors Plus Aspirin Versus Aspirin Alone in Patients With Minor Stroke or High-Risk Transient Ischemic Attack Zi-Xiao Li et al. Stroke . 2021 . Show details Display options Display options Format Stroke Actions . 2021 May 27 (...) Register of Controlled Trials, and the Cochrane Library were searched for randomized controlled trials that included patients with a diagnosis of an acute mild ischemic stroke or high-risk transient ischemic attack, intervention of DAPT therapy with clopidogrel/ticagrelor and aspirin versus aspirin alone from January 2012 to July 2020. The outcomes included subsequent stroke, all-cause mortality, cardiovascular death, hemorrhage (mild, moderate, or severe), and myocardial infarction. A DerSimonian

2021 EvidenceUpdates

6. Benefits and Risks of Dual Versus Single Antiplatelet Therapy for Secondary Stroke Prevention: A Systematic Review for the 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack (Full text)

Benefits and Risks of Dual Versus Single Antiplatelet Therapy for Secondary Stroke Prevention: A Systematic Review for the 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack Benefits and Risks of Dual Versus Single Antiplatelet Therapy for Secondary Stroke Prevention: A Systematic Review for the 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack - PubMed This site needs JavaScript to work properly (...) Prevention: A Systematic Review for the 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack , , , , , , , , , PMID: 34024115 DOI: Item in Clipboard Benefits and Risks of Dual Versus Single Antiplatelet Therapy for Secondary Stroke Prevention: A Systematic Review for the 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack Devin L Brown et al. Stroke . 2021 . Show details Display options Display options Format

2021 EvidenceUpdates PubMed abstract

7. Long-term physiotherapy in patients after stroke, with multiple sclerosis, or with Parkinson's disease

Stroke 3.1.1.1 Disease description According to the World Health Organization (WHO), stroke is defined as: “rapidly developing clinical signs of focal (or global) disturbance of cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than of vascular origin and includes cerebral infarction, intracerebral haemorrhage and subarachnoid haemorrhage.” 1 Stroke is classified into two major types based on aetiology: ischaemic and haemorrhagic. 2 (...) Ischaemic stroke is a neurological dysfunction episode caused by focal cerebral, spinal or retinal infarction, with symptoms persisting for more than 24 hours. Ischaemic cerebral infarction is commonly caused by atherosclerotic obstruction (i.e. main atherosclerotic lesion/thrombosis and embolism) of large cerebral and cervical arteries. Ischaemia can occur in all or part of the brain supplied by the occluded artery. Haemorrhagic stroke is caused by a rupture in the wall of blood vessels in the brain

2021 Swiss Federal Office of Public Health HTA

8. 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack (Full text)

2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association | Stroke Search Search Hello Guest! Login to your account Email Password Keep me logged in Search Search 2021 This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. Free Access Review (...) Article Share on Jump to Free Access Review Article 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association , MD, FAHA, Chair , MD, FAHA, Vice Chair , MD, FAHA , MD, MSc, FAHA , MD, MPH , BS, FAHA , MD , MD , MD, MPH, FAHA , MD, MS, FAHA , PhD , MD, FAHA , MD, FAHA , MD , MD, PhD , MD, MPH, FAHA , MD, FAHA , MD, MS, FAHA MD, FAHA Dawn O. Kleindorfer , Amytis Towfighi , Seemant

2021 American Heart Association PubMed abstract

9. Perioperative Neurological Evaluation and Management to Lower the Risk of Acute Stroke in Patients Undergoing Noncardiac, Nonneurological Surgery: A Scientific Statement From the American Heart Association/American Stroke Association (Full text)

of multiple risk factors further increasing the risk of perioperative stroke. In addition, patients undergoing emergency surgery or certain types of surgical procedures (thoracic, head and neck, intra-abdominal, vascular, transplant, orthopedic) were at higher risk. , Silent Cerebral Ischemia Silent brain infarctions, sometimes known as covert strokes, are acute ischemic events that are not clinically apparent. These infarcts are typically identified by brain imaging and have been associated (...) 2017, American Medical Association. All rights reserved. Numerous studies have consistently identified advancing age, renal disease, and prior transient ischemic attack/stroke as key risk factors for perioperative stroke. , , , , , Other risk factors have been identified as independent predictors, , , , such as myocardial infarction within 6 months, atrial fibrillation, hypertension, chronic obstructive pulmonary disease, current smoking, female sex, and diabetes mellitus, with the presence

2021 American Heart Association PubMed abstract

10. Longer-term health and social care strategies for stroke survivors and their carers: the LoTS2Care research programme including cluster feasibility RCT (Full text)

Longer-term health and social care strategies for stroke survivors and their carers: the LoTS2Care research programme including cluster feasibility RCT Longer-term health and social care strategies for stroke survivors and their carers: the LoTS2Care research programme including cluster feasibility RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose (...) a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} This research programme described the longer-term needs of stroke survivors, highlighting evidence and service gaps, and demonstrated feasibility to progress to a full trial of the developed intervention, New Start. {{author}} {{($index

2021 NIHR HTA programme PubMed abstract

11. Effect of prehospital workflow optimization on treatment delays and clinical outcomes in acute ischemic stroke: A systematic review and meta-analysis

Effect of prehospital workflow optimization on treatment delays and clinical outcomes in acute ischemic stroke: A systematic review and meta-analysis Effect of prehospital workflow optimization on treatment delays and clinical outcomes in acute ischemic stroke: A systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features (...) Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Acad Emerg Med Actions . 2021 Jan 2. doi: 10.1111/acem.14204. Online ahead of print. Effect of prehospital workflow optimization on treatment delays and clinical outcomes in acute ischemic stroke: A systematic review and meta-analysis , , Affiliations Expand Affiliations 1 Neurovascular Imaging Laboratory, Ingham

2021 EvidenceUpdates

12. Liuzijue qigong versus traditional breathing training for patients with post-stroke dysarthria complicated by abnormal respiratory control: Results of a single-center randomized controlled trial (Full text)

Liuzijue qigong versus traditional breathing training for patients with post-stroke dysarthria complicated by abnormal respiratory control: Results of a single-center randomized controlled trial Liuzijue qigong versus traditional breathing training for patients with post-stroke dysarthria complicated by abnormal respiratory control: Results of a single-center randomized controlled trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set (...) : Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Clin Rehabil Actions . 2021 Feb 1;269215521992473. doi: 10.1177/0269215521992473. Online ahead of print. Liuzijue qigong versus traditional breathing training for patients with post-stroke dysarthria complicated by abnormal respiratory

2021 EvidenceUpdates PubMed abstract

13. Validation of risk scores for ischaemic stroke in atrial fibrillation across the spectrum of kidney function (Full text)

Validation of risk scores for ischaemic stroke in atrial fibrillation across the spectrum of kidney function Validation of risk scores for ischaemic stroke in atrial fibrillation across the spectrum of kidney function - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 Information Show account info Close Account Logged (...) Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Eur Heart J Actions . 2021 Apr 14;42(15):1476-1485. doi: 10.1093/eurheartj/ehab059. Validation of risk scores for ischaemic stroke in atrial fibrillation across the spectrum of kidney function , , , , , , , Affiliations Expand Affiliations 1 Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands. 2 Department of Internal Medicine, Leiden

2021 EvidenceUpdates PubMed abstract

14. Safety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial

of Vascular Translational Science, INSERM, Paris, France; FHU NeuroVasc, Assistance Publique-Hôpitaux de Paris, Paris, France. 19 Diagnostic Imaging and Radiology Department, Rothschild Foundation Hospital, Paris, France. PMID: 33647246 DOI: Item in Clipboard Randomized Controlled Trial Safety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial Mikael Mazighi et al. Lancet (...) adults (aged ≥18 years) with an acute ischaemic stroke due to a large-vessel occlusion that was successfully treated with endovascular therapy. Patients were randomly assigned (1:1) to either an intensive systolic blood pressure target group (100-129 mm Hg) or a standard care systolic blood pressure target group (130-185 mm Hg), by means of a central web-based procedure, stratified by centre and intravenous thrombolysis use before endovascular therapy. In both groups, the target systolic blood

2021 EvidenceUpdates

15. Dabigatran or Aspirin in East Asian Patients With Embolic Stroke of Undetermined Source: RE-SPECT ESUS Subgroup Analysis

.). 2 Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan (K.T.). 3 Department of Neurology, Hallym Neurological Institute, Hallym University College of Medicine, Seoul, South Korea (B.-C.L.). 4 Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taiwan (C.-W.L.). 5 Division of Neurology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin (L.K.S.W.). 6 Clinical (...) or Aspirin in East Asian Patients With Embolic Stroke of Undetermined Source: RE-SPECT ESUS Subgroup Analysis Shinichiro Uchiyama et al. Stroke . 2021 Mar . Show details Display options Display options Format Stroke Actions . 2021 Mar;52(3):1069-1073. doi: 10.1161/STROKEAHA.120.031891. Epub 2021 Feb 16. Authors , , , , , , , , , , Affiliations 1 Clinical Research Centre for Medicine, International University of Health and Welfare, Tokyo, Japan (S.U.). 2 Department of Cerebrovascular Medicine, National

2021 EvidenceUpdates

16. Intra-Arterial Adjunctive Medications for Acute Ischemic Stroke During Mechanical Thrombectomy: A Meta-Analysis

and purpose: In patients with acute ischemic stroke with large vessel occlusion, the role of intra-arterial adjunctive medications (IAMs), such as urokinase, tPA (tissue-type plasminogen activator), or glycoprotein IIb/IIIa inhibitors, during mechanical thrombectomy (MT) has not been clearly established. We aim to evaluate the efficacy and safety of concomitant or rescue IAM for acute ischemic stroke with large vessel occlusion patients undergoing MT. Methods: We searched Medline, Embase, and Cochrane (...) Stroke Group Trials Register databases from inception until March 13, 2020. We analyzed all studies with patients diagnosed with acute ischemic stroke with large vessel occlusion in the anterior or posterior circulation that provided data for the two treatment arms, (1) MT+IAM and (2) MT only, and also reported on at least one of the following efficacy outcomes, recanalization and 90-day modified Rankin Scale, or safety outcomes, symptomatic intracranial hemorrhage and 90-day mortality. Data were

2021 EvidenceUpdates

17. Early Apixaban Use Following Stroke in Patients With Atrial Fibrillation: Results of the AREST Trial

transformation as AF strokes are typically larger and hemorrhagic transformation-prone. Later anticoagulation may prevent hemorrhagic transformation but increases risk of secondary stroke in this time frame. Our aim was to compare early anticoagulation with apixaban in AF patients with stroke or transient ischemic attack (TIA) versus warfarin administration at later intervals. Methods: AREST (Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation) was an open-label (...) College of Nursing (T.M.B.), University of South Florida. 9 Department of Cardiology, College of Medicine, University of Louisville, KY (M.S.). 10 Tampa General Hospital, FL (B.K.). PMID: 33626904 DOI: Item in Clipboard Full text links Cite Display options Display options Format Abstract Background and purpose: It is unknown when to start anticoagulation after acute ischemic stroke (AIS) from atrial fibrillation (AF). Early anticoagulation may prevent recurrent infarctions but may provoke hemorrhagic

2021 EvidenceUpdates

18. In patients with acute, proximal anterior circulation stroke, is endovascular treatment (EVT) alone noninferior to EVT plus intravenous thrombolysis (IVT)? (Full text)

. Radecki Affiliations Christchurch Hospital, Christchurch, New Zealand Rory S. Spiegel Affiliations MEDStar Washington Hospital, Washington, DC DOI: Article in Review Zi W, Qiu Z, Li F, et al. Effect of endovascular treatment alone vs intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke: the DEVT randomized clinical trial. JAMA . 2021;325:234-243. What Question Did This Investigation Aim to Answer? In patients with acute, proximal anterior (...) circulation stroke, is endovascular treatment (EVT) alone noninferior to EVT plus intravenous thrombolysis (IVT)? What Study Design Did the Authors Choose? Design: Open-label, randomized interventional trial. Setting: Thirty-three stroke centers in China. Population: Two hundred thirty-four adult patients with proximal, anterior circulation, intracranial, occlusion strokes with 4.5 hours of symptom onset and eligible for IVT. Intervention: EVT versus EVT plus IVT. Primary and Secondary Outcomes

2021 Annals of Emergency Medicine Journal Club PubMed abstract

19. Robotics and functional electrical stimulation for stroke rehabilitation

Robotics and functional electrical stimulation for stroke rehabilitation Robotics and functional electrical stimulation for stroke rehabilitation - Repository of AIHTA GmbH English | Browse - - - Robotics and functional electrical stimulation for stroke rehabilitation Goetz, G. and Walter, M. and Wohlhöfner, K. and Wittenberg, H. and Saal, S. and Stephan, K.M. and Dohle, C. (2021): Robotics and functional electrical stimulation for stroke rehabilitation. HTA-Projektbericht 128. Preview - Sie (...) müssen einen PDF-Viewer auf Ihrem PC installiert haben wie z. B. , oder 1MB Abstract Post-stroke patients often suffer from a hemiparesis affecting the functional abilities of lower and/or upper extremities. Improving walking and everyday activities are therefore important rehabilitation goals for these patients. Robotic assisted rehabilitation (RAR) and functional electrostimulation (FES) can, among others, be used as a supplement to conventional rehabilitation in post-stroke patients. The purpose

2021 Austrian Institute of Health Technology Assessment

20. Efficacy and Safety of Intravenous Mesenchymal Stem Cells for Ischemic Stroke

recovery in patients with chronic major stroke. Methods: In this prospective, open-label, randomized controlled trial with blinded outcome evaluation, patients with severe middle cerebral artery territory infarct within 90 days of symptom onset were assigned, in a 2:1 ratio, to receive preconditioned autologous MSC injections (MSC group) or standard treatment alone (control group). The primary outcome was the score on the modified Rankin Scale (mRS) at 3 months. The secondary outcome was to further (...) Efficacy and Safety of Intravenous Mesenchymal Stem Cells for Ischemic Stroke Efficacy and Safety of Intravenous Mesenchymal Stem Cells for Ischemic Stroke - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Show account info Close Account Logged in as: username Search: Search Save

2021 EvidenceUpdates