Latest & greatest articles for sepsis

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Top results for sepsis

1. Evaluation of Sepsis-Induced Coagulopathy in Critically Ill Pediatric Patients with Septic Shock

Evaluation of Sepsis-Induced Coagulopathy in Critically Ill Pediatric Patients with Septic Shock Evaluation of Sepsis-Induced Coagulopathy in Critically Ill Pediatric Patients with Septic Shock - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health (...) ? Report format: Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Thromb Haemost Actions . 2020 Oct 29. doi: 10.1055/s-0040-1718736. Online ahead of print. Evaluation of Sepsis-Induced Coagulopathy

2020 EvidenceUpdates

2. The index of oxygenation to respiratory rate as a prognostic factor for mortality in Sepsis

The index of oxygenation to respiratory rate as a prognostic factor for mortality in Sepsis The index of oxygenation to respiratory rate as a prognostic factor for mortality in Sepsis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from (...) as a prognostic factor for mortality in Sepsis , , , , , , , , , Affiliations Expand Affiliations 1 Department of Emergency Medicine, Seoul National University Bundang Hospital 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do 13620, Republic of Korea. 2 Department of Emergency Medicine, Seoul National University Bundang Hospital 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do 13620, Republic of Korea; Department of Emergency Medicine, Seoul National University College of Medicine

2020 EvidenceUpdates

3. Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial Full Text available with Trip Pro

Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC: . Get (...) : Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Chest Actions . 2020 Oct;158(4):1431-1445. doi: 10.1016/j.chest.2020.04.025. Epub 2020 Apr 27. Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized

2020 EvidenceUpdates

4. Diagnosis and management of sepsis in the paediatric patient

Diagnosis and management of sepsis in the paediatric patient Sepsis is a systemic inflammatory response to suspected or proven infection. Given its importance in terms of morbidity and mortality, a number of initiatives by several professional societies in recent years have led to the development of guidelines for the recognition and timely management of sepsis. The principal elements of the most recent guidelines are summarized in this practice point. These elements include (...) : recognition of changes in clinical condition and vital signs, such as fever, tachycardia, and changes in peripheral perfusion, which should raise concern for sepsis; initial stabilization of airway, breathing, and circulation; timely administration of empiric antimicrobial therapy; use of fluid boluses and vasoactive medications; and specific considerations in patients with underlying medical conditions, such as the use of corticosteroids for possible adrenal insufficiency due to hypothalamic-adrenal

2020 Canadian Paediatric Society

5. Emergency Severity Index as a predictor of in-hospital mortality in suspected sepsis patients in the emergency department

Emergency Severity Index as a predictor of in-hospital mortality in suspected sepsis patients in the emergency department Emergency Severity Index as a predictor of in-hospital mortality in suspected sepsis patients in the emergency department - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving (...) Severity Index as a predictor of in-hospital mortality in suspected sepsis patients in the emergency department , , , , Affiliations Expand Affiliations 1 Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. 2 Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. Electronic address: kpraew@kku.ac.th. PMID: 32739856 DOI: Item in Clipboard Emergency Severity Index as a predictor of in-hospital mortality in suspected

2020 EvidenceUpdates

6. Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study. (Abstract)

Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study. Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a high mortality. This study assessed venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for sepsis-induced cardiogenic shock refractory to conventional treatments.In this retrospective, multicentre, international cohort study, we compared outcomes of 82 (...) treated at the largest centre reported satisfactory Short Form-36 evaluated health-related quality of life at 1-year follow-up.Patients with severe sepsis-induced cardiogenic shock treated with VA-ECMO had a large and significant improvement in survival compared with controls not receiving ECMO. However, despite the careful propensity-weighted analysis, we cannot rule out unmeasured confounders.None.Copyright © 2020 Elsevier Ltd. All rights reserved.

2020 Lancet

7. Outcome of Immediate Versus Early Antibiotics in Severe Sepsis and Septic Shock: A Systematic Review and Meta-analysis Full Text available with Trip Pro

Outcome of Immediate Versus Early Antibiotics in Severe Sepsis and Septic Shock: A Systematic Review and Meta-analysis Outcome of Immediate Versus Early Antibiotics in Severe Sepsis and Septic Shock: A Systematic Review and Meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving (...) at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Review Ann Emerg Med Actions . 2020 Jun 24;S0196-0644(20)30337-1. doi: 10.1016/j.annemergmed.2020.04.042. Online ahead of print. Outcome of Immediate Versus Early Antibiotics in Severe Sepsis

2020 EvidenceUpdates

8. Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock: A Randomized Controlled Trial

Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock: A Randomized Controlled Trial Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly (...) at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Chest Actions . 2020 Jul;158(1):174-182. doi: 10.1016/j.chest.2020.02.065. Epub 2020 Mar 31. Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock: A Randomized

2020 EvidenceUpdates

9. Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis: The ORANGES Trial Full Text available with Trip Pro

Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis: The ORANGES Trial Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis: The ORANGES Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID (...) , Thiamine, and Glucocorticoids in the Early Treatment of Sepsis: The ORANGES Trial , , , , , Affiliations Expand Affiliations 1 Department of Critical Care, Department of Nephrology, Community Medical Center, Toms River, NJ; Department of Nephrology, Jersey Shore University Medical Center, Hackensack Meridian School of Medicine at Seton Hall, Neptune, NJ. Electronic address: jiglesias23@gmail.com. 2 Department of Pharmacy, Community Medical Center, Toms River, NJ. 3 Fairleigh Dickinson University School

2020 EvidenceUpdates

10. SARS-CoV-2 and viral sepsis: observations and hypotheses. Full Text available with Trip Pro

SARS-CoV-2 and viral sepsis: observations and hypotheses. Since the outbreak of coronavirus disease 2019 (COVID-19), clinicians have tried every effort to understand the disease, and a brief portrait of its clinical features have been identified. In clinical practice, we noticed that many severe or critically ill COVID-19 patients developed typical clinical manifestations of shock, including cold extremities and weak peripheral pulses, even in the absence of overt hypotension. Understanding (...) the mechanism of viral sepsis in COVID-19 is warranted for exploring better clinical care for these patients. With evidence collected from autopsy studies on COVID-19 and basic science research on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV, we have put forward several hypotheses about SARS-CoV-2 pathogenesis after multiple rounds of discussion among basic science researchers, pathologists, and clinicians working on COVID-19. We hypothesise that a process called viral sepsis

2020 Lancet

11. Surviving Sepsis Campaign International Guidelines

Surviving Sepsis Campaign International Guidelines STATEMENT OF ENDORSEMENT Surviving Sepsis Campaign International Guidelines In July 2019, the American Academy of Pediatrics endorsed the following publication: Weiss SL, Peters MJ, Alhazzani W, et al. Surviving Sepsis Campaigninternationalguidelinesfor themanagementofsepticshockand sepsis-associated organ dysfunction in children. Pediatr Crit Care Med. 2020;21(2):e52–e106. Available at: https://journals.lww.com/pccmjourna l/Fulltext/2020/02000 (...) /Surviving_Sepsis_Campaign_International_Guideli nes.20.aspx. All statements of endorsement from the American Academy of Pediatrics automatically expire 5 years after publication unless reaf?rmed, revised, or retired at or before that time. DOI: https://doi.org/10.1542/peds.2020-0629 Copyright © 2020 by the American Academy of Pediatrics To cite: Surviving Sepsis Campaign International Guidelines. Pediatrics. 2020;145(5):e20200629 PEDIATRICS Volume 145, number 5, May 2020:e20200629 FROM THE AMERICAN ACADEMY OF PEDIATRICS by guest on May 15

2020 American Academy of Pediatrics

12. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Full Text available with Trip Pro

Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Surviving Sepsis Campaign: Guidelines on the Management of C... : Read Online: Critical Care Medicine | Society of Critical Care Medicine ')} You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Your account has been temporarily locked Your account has been temporarily locked due to incorrect sign in attempts (...) , Assessment, Development and Evaluation (GRADE) approach, then generated recommendations based on the balance between benefit and harm, resource and cost implications, equity, and feasibility. Recommendations were either strong or weak, or in the form of best practice recommendations. Results: The Surviving Sepsis Campaign COVID-19 panel issued 54 statements, of which four are best practice statements, nine are strong recommendations, and 35 are weak recommendations. No recommendation was provided for six

2020 Society of Critical Care Medicine

13. Screening strategies to identify sepsis in the prehospital setting: a validation study Full Text available with Trip Pro

Screening strategies to identify sepsis in the prehospital setting: a validation study Screening Strategies to Identify Sepsis in the Prehospital Setting: A Validation Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health U.S. National Library (...) navigation CMAJ Actions . 2020 Mar 9;192(10):E230-E239. doi: 10.1503/cmaj.190966. Screening Strategies to Identify Sepsis in the Prehospital Setting: A Validation Study , , , , , , Affiliations Expand Affiliations 1 Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health (Lane, Wunsch, Saskin, Lin, Scales), Interdepartmental Division of Critical Care (Wunsch, Scales), Division of Emergency Medicine, Department of Family and Community Medicine (Cheskes), and Division

2020 EvidenceUpdates

14. Sepsis and the Emergency Department

Sepsis and the Emergency Department Patron: HRH Princess Royal 7-9 Bream’s Buildings Tel +44 (0)20 7404 1999 London Fax +44 (0)20 7067 1267 EC4A 1DT www.rcem.ac.uk Position statement Sepsis and the Emergency Department November 2019 Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection [1] . Sepsis is a life-threatening condition that arises when the response to an infection injures tissues and organs . Septic shock is a subset of sepsis (...) in which underlying circulatory and cellular/metabolic abnormalities are profound enough to substantially increase mortality [2]. An article recently published in the Lancet has provoked some interest with regards to how sepsis may be presented in the media [3]. Patients attending the Emergency Department as a result of infection represent a significantly larger group than those attending with sepsis or septic shock. Whilst recognizing that the incidence of ‘true sepsis’ or septic shock is relatively

2020 Royal College of Emergency Medicine

15. Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants. (Abstract)

Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants. Lactoferrin, a normal component of human colostrum and milk, can enhance host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis (NEC) in preterm neonates.To assess the safety and effectiveness of lactoferrin supplementation to enteral feeds for prevention of sepsis and NEC in preterm neonates. Secondarily, we assessed the effects of lactoferrin (...) to 20 January 2020), Embase (1980 to 20 January 2020), and CINAHL (1982 to 20 January 2020). We also searched clinical trials databases, conference proceedings, and the reference lists of retrieved articles for randomized controlled trials and quasi-randomized trials.In our search, we included randomized controlled trials (RCTs) evaluating enteral lactoferrin supplementation at any dose or duration to prevent sepsis or NEC in preterm neonates.We used the standard methods of Cochrane Neonatal

2020 Cochrane

16. Long-term courses of sepsis survivors: effects of a primary care management intervention (Abstract)

Long-term courses of sepsis survivors: effects of a primary care management intervention Sepsis survivors face mental and physical sequelae even years after discharge from the intensive care unit. The aim of this study was to evaluate the long-term courses of sepsis survivors and the effects of a primary care management intervention in sepsis aftercare.This study presents a 24-month follow-up of a randomized controlled trial that recruited 291 patients who survived sepsis (including septic (...) shock) from nine German intensive care units. Participants were randomized to usual care (n=143) or to a 12-month-intervention (n=148). The intervention included training of patients and their primary care physicians (PCP) in evidence-based post-sepsis care, case management provided by trained nurses, and clinical decision support for PCPs by consulting physicians. Usual care was provided by PCPs in the control group. At the 24-month follow-up, 12 months after the 1-year-intervention, survival

2020 EvidenceUpdates

17. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children Full Text available with Trip Pro

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children Surviving Sepsis Campaign International Guidelines for the M... : Pediatric Critical Care Medicine ')} You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Your account has been temporarily locked Your account has been temporarily locked due to incorrect sign in attempts (...) , PA. 15 Texas Children’s Hospital, Houston, TX. 16 Paris South University Hospitals—Assistance Publique Hopitaux de Paris, Paris, France. 17 Physiopathology and Therapeutic Innovation Unit—INSERM U999, South Paris-Saclay University, Paris, France. 18 King’s College Hospital, London, United Kingdom. 19 University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, United Kingdom. 20 The Latin America Sepsis Institute, São Paulo, Brazil. 21 Nationwide Children’s

2020 Society of Critical Care Medicine

18. Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. Full Text available with Trip Pro

Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. Sepsis is life-threatening organ dysfunction due to a dysregulated host response to infection. It is considered a major cause of health loss, but data for the global burden of sepsis are limited. As a syndrome caused by underlying infection, sepsis is not part of standard Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) estimates. Accurate estimates (...) are important to inform and monitor health policy interventions, allocation of resources, and clinical treatment initiatives. We estimated the global, regional, and national incidence of sepsis and mortality from this disorder using data from GBD 2017.We used multiple cause-of-death data from 109 million individual death records to calculate mortality related to sepsis among each of the 282 underlying causes of death in GBD 2017. The percentage of sepsis-related deaths by underlying GBD cause in each

2020 Lancet

19. Extracorporeal cytokine haemadsorption therapy in patients with sepsis or SIRS. Update 2020. Decision Support Document 106/ Update 2020.

Extracorporeal cytokine haemadsorption therapy in patients with sepsis or SIRS. Update 2020. Decision Support Document 106/ Update 2020. Extracorporeal cytokine haemadsorption therapy in patients with sepsis or SIRS. Update 2020 - Repository of AIHTA GmbH English | Browse - - - Extracorporeal cytokine haemadsorption therapy in patients with sepsis or SIRS. Update 2020 Götz, G. and Hawlik, K. (2020): Extracorporeal cytokine haemadsorption therapy in patients with sepsis or SIRS. Update 2020 (...) . Decision Support Document 106/ Update 2020. Preview - Sie müssen einen PDF-Viewer auf Ihrem PC installiert haben wie z. B. , oder 876kB Abstract Extracorporeal cytokine adsorption therapy (ECAT) aims to reduce the cytokine concentration in the blood, thereby stabilising the overall immune response in sepsis and SIRS (Systemic Inflammatory Response Syndrome). We investigated the efficacy and safety of ECAT in its two main indications: to treat sepsis and to prevent SIRS (Systemic Inflammatory Response

2020 Austrian Institute of Health Technology Assessment

20. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Intensive Care Medicine GUIDELINES Un-edited accepted proof* © European Society of Intensive Care Medicine and the Society of Critical Care Medicine 2020 1 Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Authors Waleed Alhazzani 1,2 , Morten Hylander Møller 3,4 , Yaseen M. Arabi 5 , Mark Loeb 1,2 (...) either strong or weak, or in the form of best practice recommendations. Results The Surviving Sepsis Campaign COVID-19 panel issued 54 statements, of which 4 are best practice statements, 9 are strong recommendations, and 35 are weak recommendations. No recommendation was provided for 6 questions. The topics were: 1) infection control, 2) laboratory diagnosis and specimens, 3) hemodynamic support, 4) ventilatory support, and 5) COVID-19 therapy. Conclusion The Surviving Sepsis Campaign COVID-19 panel

2020 Covid-19 Ad hoc guidelines