Latest & greatest articles for pregnancy

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pregnancy or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on pregnancy and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for pregnancy

1. Pregnancy outcome and cost-effectiveness comparisons of artificial cycle-prepared frozen embryo transfer with or without GnRH agonist pretreatment for polycystic ovary syndrome: a randomised controlled trial

Pregnancy outcome and cost-effectiveness comparisons of artificial cycle-prepared frozen embryo transfer with or without GnRH agonist pretreatment for polycystic ovary syndrome: a randomised controlled trial Pregnancy outcome and cost-effectiveness comparisons of artificial cycle-prepared frozen embryo transfer with or without GnRH agonist pretreatment for polycystic ovary syndrome: a randomised controlled trial - PubMed This site needs JavaScript to work properly. Please enable it to take (...) Cite Display options Display options Format Share Permalink Copy Page navigation BJOG Actions . 2020 Aug 11. doi: 10.1111/1471-0528.16461. Online ahead of print. Pregnancy outcome and cost-effectiveness comparisons of artificial cycle-prepared frozen embryo transfer with or without GnRH agonist pretreatment for polycystic ovary syndrome: a randomised controlled trial , , , , , Affiliations Expand Affiliation 1 The Center of Reproductive Medicine, First Affiliated Hospital, Sun Yat-sen University

2020 EvidenceUpdates

2. Continuous glucose monitoring in pregnant women with type 1 diabetes

in pregnant women with T1DM is supported by the clinical evidence. The use of CGM during pregnancy may improve maternal glycaemic control compared with self- monitoring of blood glucose (SMBG). CGM reduces neonatal hypoglycaemia and the need for and duration of neonatal intensive care. These improved clinical outcomes were reported in women who used CGM from the first trimester of pregnancy. Cost modelling estimates that the use of CGM in mothers with T1DM is cost saving compared with SMBG, with cost (...) for NHSScotland. Epidemiology and predicted volume According to Diabetes UK, 5% of the 956,861 pregnancies in the UK in 2015 involved diabetes: ? 42,000 involved gestational diabetes (87.5%) ? 3,600 involved T1DM (7.5%) ? 2,400 involved type 2 diabetes (5%) 2 The number of women in Scotland with T1DM who became pregnant rose from 205 in 1998/99 to 264 in 2012/13 3 . Scottish context The Scottish Intercollegiate Guidelines Network (SIGN) guideline on The Management of Diabetes (published in 2010 and updated

2020 SHTG Advice Statements

3. SMFM Special Statement: Updated checklists for pregnancy management in persons with HIV

-Fetal Medicine ∗ Kelly S. Gibson Affiliations Society for Maternal-Fetal Medicine, 409 12 St. SW, Washington, DC 20024, USA. pubs@smfm.org Lorraine E. Toner Affiliations Society for Maternal-Fetal Medicine, 409 12 St. SW, Washington, DC 20024, USA. pubs@smfm.org Published: August 27, 2020 DOI: Optimal management of HIV-positive pregnant individuals involves many specific interventions made by many healthcare professionals at specific time-points before, during, and after pregnancy. Errors (...) SMFM Special Statement: Updated checklists for pregnancy management in persons with HIV Society for Maternal-Fetal Medicine Special Statement: Updated checklists for pregnancy management in persons with HIV - American Journal of Obstetrics & Gynecology Go search , PB6-B11, November 01, 2020 Powered By Mendeley Share on Society for Maternal-Fetal Medicine Special Statement: Updated checklists for pregnancy management in persons with HIV Patient Safety and Quality Committee, Society for Maternal

2020 Society for Maternal-Fetal Medicine

4. SMFM Special Statement: Updated checklists for management of monochorionic twin pregnancy

SMFM Special Statement: Updated checklists for management of monochorionic twin pregnancy Society for Maternal-Fetal Medicine Special Statement: Updated checklists for management of monochorionic twin pregnancy - American Journal of Obstetrics & Gynecology Go search , PB16-B20, November 01, 2020 Powered By Mendeley Share on Society for Maternal-Fetal Medicine Special Statement: Updated checklists for management of monochorionic twin pregnancy Patient Safety and Quality Committee, Society (...) for Maternal-Fetal Medicine ∗ Iffath Abbasi Hoskins Affiliations Society for Maternal-Fetal Medicine, 409 12 St. SW, Washington, DC 20024, USA. pubs@smfm.org C. Andrew Combs Affiliations Society for Maternal-Fetal Medicine, 409 12 St. SW, Washington, DC 20024, USA. pubs@smfm.org Published: August 26, 2020 DOI: Approximately 20% of twin pregnancies are monochorionic. The management of monochorionic twin pregnancy involves several additional interventions beyond the routine management of singletons

2020 Society for Maternal-Fetal Medicine

5. Sonographic Cervical Length in Singleton Pregnancies: Techniques and Clinical Applications

Sonographic Cervical Length in Singleton Pregnancies: Techniques and Clinical Applications Guideline No. 401: Sonographic Cervical Length in Singleton Pregnancies: Techniques and Clinical Applications - Journal of Obstetrics and Gynaecology Canada Go search , P1394-1413.e1, November 01, 2020 Powered By Mendeley Share on Guideline No. 401: Sonographic Cervical Length in Singleton Pregnancies: Techniques and Clinical Applications Kenneth I. Lim Correspondence Corresponding author: Kenneth I. Lim (...) Cousens S Zupan J Lancet Neonatal Survival Steering T 4 million neonatal deaths: when? Where? Why?. Lancet. 2005; 365 ( Available from: ) : 891-900 Joseph KS Kramer MS Marcoux S Ohlsson A Wen SW Allen A et al. Determinants of preterm birth rates in Canada from 1981 through 1983 and from 1992 through 1994. N Engl J Med. 1998; 339 ( Available from: ) : 1434-1439 Allen VM Wilson RD Cheung A Genetics Committee, Reproductive Endocrinology and Infertility Committee Pregnancy outcomes after assisted

2020 Society of Obstetricians and Gynaecologists of Canada

6. Mind-body interventions on stress management in pregnant women: A systematic review and meta-analysis of randomized controlled trials

Mind-body interventions on stress management in pregnant women: A systematic review and meta-analysis of randomized controlled trials Mind-body interventions on stress management in pregnant women: A systematic review and meta-analysis of randomized controlled trials - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 (...) . Online ahead of print. Mind-body interventions on stress management in pregnant women: A systematic review and meta-analysis of randomized controlled trials , , , , , , , Affiliations Expand Affiliations 1 School of Nursing, Jilin University, Changchun, Jilin, China. 2 Department of Developmental Pediatrics, Second Hospital of Jilin University, Changchun, Jilin, China. PMID: 33048358 DOI: Item in Clipboard Review Mind-body interventions on stress management in pregnant women: A systematic review

2020 EvidenceUpdates

7. Doxylamine during pregnancy: minimise dose and duration, due to possible link with malformations

Doxylamine during pregnancy: minimise dose and duration, due to possible link with malformations Prescrire IN ENGLISH - Spotlight ''Doxylamine during pregnancy: minimise dose and duration, due to possible link with malformations'', 1 November 2020 {1} {1} {1} | | > > > Doxylamine during pregnancy: minimise dose and duration, due to possible link with malformations Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |  (...)  |   |   |   |   |  Spotlight Doxylamine during pregnancy: minimise dose and duration, due to possible link with malformations FEATURED REVIEW Prescrire's analyses have for many years found doxylamine to be the first-choice antiemetic drug in early pregnancy, when non-pharmacological measures fail. A recent study suggests an increased risk of major birth defects. Does this finding affect doxylamine's harm-benefit balance and its place as the first-choice drug

2020 Prescrire

8. Management of post-term pregnancies. Systematic review

Management of post-term pregnancies. Systematic review Management of post-term pregnancies - NIPH Search for: Søk Menu To top level Close Infectious diseases & Vaccines Mental & Physical health Environment & Lifestyle Health in Norway Quality & Knowledge Research & Access to data About NIPH Close Management of post-term pregnancies Subscribe me! You have subscribed to alerts about: Management of post-term pregnancies Oops, something went wrong... ... contact nettredaksjon@fhi.no. ... reload (...) the page and try again- Systematic review Management of post-term pregnancies. Systematic review Published 22.09.2020 We have carried out a systematic review of four randomised tri-als to examine the effects of inducting labour at or beyond 41 weeks (+ 0-2 days) of gestation compared with monitoring up to 42 weeks (+ 0-2 days). We have carried out a systematic review of four randomised tri-als to examine the effects of inducting labour at or beyond 41 weeks (+ 0-2 days) of gestation compared

2020 Norwegian Institute of Public Health

9. Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic

Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic COVID-19: Guidance for the remobilisation of services within health and care settings Infection prevention and control recommendations Uncontrolled if printed. COVID-19: infection prevention and control guidance About this guidance The guidance is issued jointly by the Department of Health and Social Care (DHSC), Public Health Wales (PHW), Public Health Agency (PHA) Northern Ireland, Health

2020 ICM Anaesthesia COVID-19

10. The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis Full Text available with Trip Pro

the global health care system from time to time. The pregnant state, with alterations in hormone levels and decreased lung volumes due to a gravid uterus and slightly immunocompromised state may predispose patients to a more rapidly deteriorating clinical course and can get a greater risk of harm for both the mother and fetus. Therefore, this systematic review was aimed to assess the effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and its possibility of vertical (...) The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features

2020 EvidenceUpdates

11. FSRH Clinical Guideline: Contraception After Pregnancy

of long-acting reversible contraception (LARC), when choosing an appropriate method to use after pregnancy. Information giving and counselling ? All clinicians involved in the care of pregnant women should provide the opportunity to discuss contraception. ? Whenever contraceptive counselling is provided, care should be taken to ensure women do not feel under pressure to choose a method of contraception. D Clinicians should adopt a person-centred approach when providing contraceptive counselling (...) . ? Clinicians who are giving advice to women about contraception after pregnancy should ensure that this information is timely, up-to-date and accurate. ? Comprehensive, unbiased and accurate information on contraceptive methods after pregnancy should be made available in different languages and formats including audio-visual. Provision of contraception ? Services providing care to pregnant women should be able to offer all appropriate methods of contraception, including LARC, to women before

2020 Faculty of Sexual & Reproductive Healthcare

12. Management of Primary Headaches in Pregnancy

). There is insufficient evidence to make conclusions about the benefits or harms of nonpharmacologic treatments used during pregnancy, including acupuncture (1 RCT); biofeedback, relaxation therapy, and physical therapy (1 RCT and 2 single-group studies); nerve blocks (1 single-group study); and transcranial magnetic stimulation (1 single-group study). Conclusions. Evidence regarding the benefits and harms of all interventions in women who are pregnant (or attempting to become pregnant), postpartum, or breastfeeding (...) . ? Venlafaxine, tricyclic antidepressants (any), benzodiazepines (any), beta blockers (any), prednisolone, and oral magnesium use during pregnancy may have increased risk of fetal/child adverse effects, but calcium channel blockers (any, but nifedipine in particular) and antihistamines (any) may have a low risk of adverse effects (indirect evidence). • Treatment of patients with acute attacks of primary headache in women who are pregnant (or attempting to become pregnant), postpartum, or breastfeeding o

2020 Effective Health Care Program (AHRQ)

13. Screening and Counselling for Alcohol Consumption During Pregnancy

. Target Population Pregnant women and women of child-bearing age and their families. Evidence Medline, EMBASE, and CENTRAL databases were searched for “alcohol use and pregnancy.” The results were filtered for a publication date between 2010 and September 2018. The search terms were developed using Medical Subject Headings terms and keywords, including pre-pregnancy, pregnant, breastfeeding, lactation, female, women, preconception care, prenatal care, fetal alcohol spectrum disorder, prenatal alcohol (...) and pregnancy outcomes. SUMMARY STATEMENTS (GRADE ratings in parentheses) 1 Alcohol is a known teratogen (high). 2 The current evidence cannot establish a safe threshold for alcohol consumption in pregnancy (high). 3 Abstaining from alcohol during pregnancy is the safest option (high). 4 Abstaining from alcohol while breastfeeding is the safest option (high). RECOMMENDATIONS (GRADE ratings in parentheses) 1 All pregnant women should be questioned about alcohol use by asking a single question

2020 Society of Obstetricians and Gynaecologists of Canada

14. Coronavirus (COVID-19) infection and pregnancy

be offered in-person as far as possible, with particular attention to those from BAME communities or those living with medical, social or psychological conditions that make them higher risk. • Appropriate screening for diabetes in pregnancy should be provided, following NICE guidance as far as possible, with awareness that changes in screening provision may be associated with a reduction in the detection of milder cases of gestational diabetes. • Open access for pregnant women to day assessment (...) ?’ 12 14.10.20 2.2 Recommendations added: • Women should be advised that vaccination against influenza is safe at all gestations of pregnancy and is recommended to protect both the woman and baby from the adverse effects of becoming seriously ill with flu during pregnancy. During the COVID-19 pandemic, it is particularly important that pregnant women take up the influenza vaccine to reduce their risk of contracting flu.4 • Appointments where physical examination is not required and where

2020 Royal College of Obstetricians and Gynaecologists

15. SARS-CoV-2 infection in pregnancy: A systematic review and meta-analysis of clinical features and pregnancy outcomes Full Text available with Trip Pro

Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK. PMID: 32838230 PMCID: DOI: Item in Clipboard Full-text links Cite Display options Display options Format Abstract Background: Perform a systematic review and meta-analysis of SARS-CoV-2 infection and pregnancy. Methods: Databases (Medline, Embase, Clinicaltrials.gov, Cochrane Library) were searched electronically on 6th April and updated regularly until 8th June 2020. Reports of pregnant women with reverse (...) SARS-CoV-2 infection in pregnancy: A systematic review and meta-analysis of clinical features and pregnancy outcomes SARS-CoV-2 infection in pregnancy: A systematic review and meta-analysis of clinical features and pregnancy outcomes - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation

2020 EvidenceUpdates

16. Clinical characteristics, prognostic factors, and maternal and neonatal outcomes of SARS-CoV-2 infection among hospitalized pregnant women: A systematic review Full Text available with Trip Pro

Free PMC article. No abstract available. References REFERENCES Johns Hopkins. Johns Hopkins Coronavirus Resource Center. https://coronavirus.jhu.edu/map.html. Accessed July 18, 2020. Moher D, Liberati A, Tetzlaff J, Altman DG; Group P. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. J Clin Epidemiol. 2009;62:1006-1012. Zhang L, Jiang Y, Wei M, et al. Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province. Zhonghua Fu Chan Ke Za (...) Clinical characteristics, prognostic factors, and maternal and neonatal outcomes of SARS-CoV-2 infection among hospitalized pregnant women: A systematic review Clinical characteristics, prognostic factors, and maternal and neonatal outcomes of SARS-CoV-2 infection among hospitalized pregnant women: A systematic review - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced

2020 EvidenceUpdates

17. Fertility preservation and post-treatment pregnancies in post-pubertal cancer patients: ESMO Clinical Practice Guidelines Full Text available with Trip Pro

Fertility preservation and post-treatment pregnancies in post-pubertal cancer patients: ESMO Clinical Practice Guidelines Fertility preservation and post-treatment pregnancies in post-pubertal cancer patients: ESMO Clinical Practice Guidelines† - Annals of Oncology Go search Powered By Mendeley Share on Fertility preservation and post-treatment pregnancies in post-pubertal cancer patients: ESMO Clinical Practice Guidelines † M. Lambertini Affiliations Department of Internal Medicine and Medical (...) of the ESMO Guidelines Committee ∗ Author Footnotes † Approved by the ESMO Guidelines Committee: June 2020. Published: September 22, 2020 DOI: Highlights: • This ESMO Clinical Practice Guideline provides recommendations for: • Fertility preservation strategies in post-pubertal cancer patients, including those with hereditary cancer syndromes • The management of post-treatment pregnancies in cancer survivors, including those with hereditary cancer syndromes • Management flowcharts for fertility

2020 European Society for Medical Oncology

18. Rapid Review Update 1: Is there an increased risk of adverse maternal or fetal outcomes in women diagnosed with COVID-19 during pregnancy?

3, 2020 Akhtar, H., Patel, C., Abuelgasim, E., & Harky, A. (2020). COVID-19 (SARS- CoV-2) infection in pregnancy: A systematic review. Gynecologic and Obstetric Investigation. Epub ahead of print. Jul 30, 2020 (Search completed May 22, 2020) P: pregnant women and their fetuses/neonates E: COVID-19 infection C: no comparator O: maternal COVID-19 symptoms, pregnancy complications, neonatal COVID- 19 symptoms, neonatal health status, delivery timing and type, vertical transmission This review (...) includes 38 studies reporting on a total of 520 pregnant women in their third trimesters with COVID-19 infections. Most studies were from China, with other studies from Italy, Peru, India, USA, Portugal, South Korea. • 2 cohort studies • 11 cross- sectional studies • 4 case control studies • 11 case reports • 10 case series reports Birth outcomes were: • 433 newborns (366 cesarean deliveries) • Delivery outcomes for remaining pregnancies not reported In a meta-analysis of 3 studies, 60 pregnant women

2020 COVID-19 Rapid Evidence Service

19. Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies. (Abstract)

Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies. Preterm birth (PTB) remains the foremost global cause of perinatal morbidity and mortality. Thus, the prevention of spontaneous PTB still remains of critical importance. In an attempt to prevent PTB in singleton pregnancies, cervical cerclage, in combination with other treatments, has been advocated. This is because, cervical cerclage is an intervention (...) that is commonly recommended in women with a short cervix at high risk of preterm birth but, despite this, many women still deliver prematurely, as the biological mechanism is incompletely understood. Additionally, previous Cochrane Reviews have been published on the effectiveness of cervical cerclage in singleton and multiple pregnancies, however, none has evaluated the effectiveness of using cervical cerclage in combination with other treatments.To assess whether antibiotics administration, vaginal pessary

2020 Cochrane

20. Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy: a randomised, double-blind, placebo-controlled trial. (Abstract)

Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy: a randomised, double-blind, placebo-controlled trial. Cytomegalovirus is a common congenital infection, with high morbidity after an early primary maternal infection. No effective means exist to prevent viral transmission to the fetus. We aimed to investigate whether valaciclovir can prevent vertical transmission of cytomegalovirus to the fetus in pregnant women with a primary (...) infection acquired early in pregnancy.This prospective, randomised, double-blind, placebo-controlled trial was done at the Infectious Feto-Maternal Clinic of Rabin Medical Center (Petach Tikvah, Israel). Pregnant women aged 18 years or older, with serological evidence of a primary cytomegalovirus infection acquired either periconceptionally or during the first trimester of pregnancy, were randomly assigned to oral valaciclovir (8 g per day, twice daily) or placebo from enrolment until amniocentesis

2020 Lancet