Latest & greatest articles for lithium

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Top results for lithium

1. Lithium during pregnancy: malformations, fetotoxicity and uncertain long-term effects

Lithium during pregnancy: malformations, fetotoxicity and uncertain long-term effects Prescrire IN ENGLISH - Spotlight ''Lithium during pregnancy: malformations, fetotoxicity and uncertain long-term effects'', 1 April 2020 {1} {1} {1} | | > > > Lithium during pregnancy: malformations, fetotoxicity and uncertain long-term effects Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |  (...)  |   |  Spotlight Lithium during pregnancy: malformations, fetotoxicity and uncertain long-term effects FEATURED REVIEW Outside the context of pregnancy, lithium is the standard "mood stabiliser" for the treatment of bipolar disorder. What are the main known short-term and long-term consequences of in utero exposure to lithium? Full review (3 pages) available for download by subscribers. Abstract A meta-analysis of about 600 pregnant women exposed to lithium during the first

2020 Prescrire

2. Lithium for acute mania. (Abstract)

Lithium for acute mania. Bipolar disorder is a common condition associated with high morbidity; developing efficacious, safe treatments is therefore essential. Lithium is an effective maintenance treatment for bipolar disorder. It acts as mood stabiliser and reduces the risk of suicide. However, evidence assessing the efficacy of lithium in the treatment of acute mania is less robust. Current evidence-based guidelines cite multiple anti-dopaminergic and mood-stabilising agents as initial (...) treatments: more definite evidence is needed to decide if lithium should be the first-line therapy.1. To assess the effects of lithium in comparison with placebo or other active treatment in alleviating the acute symptoms of a manic or mixed episode in people with bipolar disorder.2. To review the acceptability and tolerability of treatment with lithium in comparison with placebo or other active treatments in alleviating the acute symptoms of a manic or mixed episode in people with bipolar disorder.We

2019 Cochrane

3. Clinical and biological effects of long-term lithium treatment in older adults with amnestic mild cognitive impairment: randomised clinical trial Full Text available with Trip Pro

Clinical and biological effects of long-term lithium treatment in older adults with amnestic mild cognitive impairment: randomised clinical trial Experimental studies indicate that lithium may facilitate neurotrophic/protective responses in the brain. Epidemiological and imaging studies in bipolar disorder, in addition to a few trials in Alzheimer's disease support the clinical translation of these findings. Nonetheless, there is limited controlled data about potential use of lithium to treat (...) or prevent dementia.AimsTo determine the benefits of lithium treatment in patients with amnestic mild cognitive impairment (MCI), a clinical condition associated with high risk for Alzheimer's disease.A total of 61 community-dwelling, physically healthy, older adults with MCI were randomised to receive lithium or placebo (1:1) for 2 years (double-blind phase), and followed-up for an additional 24 months (single-blinded phase) (trial registration at clinicaltrials.gov: NCT01055392). Lithium carbonate

2019 EvidenceUpdates

4. Answer to the letter to the editor of Y. Li et al. concerning "Intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: a prospective randomized double-blind sham-controlled multi-center study" by Fischgrund JS, et al. [Eur Sp Full Text available with Trip Pro

Answer to the letter to the editor of Y. Li et al. concerning "Intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: a prospective randomized double-blind sham-controlled multi-center study" by Fischgrund JS, et al. [Eur Sp 31399848 2019 08 30 1432-0932 28 9 2019 Sep European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society Eur Spine J Answer (...) to the letter to the editor of Y. Li et al. concerning "Intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: a prospective randomized double-blind sham-controlled multi-center study" by Fischgrund JS, et al. [Eur Spine J; (2018) 27(5): 1146-1156]. 2224 10.1007/s00586-019-06063-5 Fischgrund Jeffrey S JS Oakland University William Beaumont School of Medicine, 3535 West 13 Mile Road, Suite 744, Royal Oak, MI, 48073, USA. jsfischgrund37@gmail.com. eng Letter 2019 08 09 Germany

2019 European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society Controlled trial quality: predicted high

5. Lies, damned lies and epidemiology: why global health needs good epidemiological practice guidelines Full Text available with Trip Pro

Lies, damned lies and epidemiology: why global health needs good epidemiological practice guidelines 30294463 2018 11 14 2059-7908 3 5 2018 BMJ global health BMJ Glob Health Lies, damned lies and epidemiology: why global health needs good epidemiological practice guidelines. e001019 10.1136/bmjgh-2018-001019 Alba Sandra S Health Unit, KIT Royal Tropical Institute, Amsterdam, The Netherlands. Mergenthaler Christina C Health Unit, KIT Royal Tropical Institute, Amsterdam, The Netherlands. eng

2018 BMJ global health

6. Lithium

Lithium Top results for lithium - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for lithium The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you

2018 Trip Latest and Greatest

7. CRACKCast E160 – Lithium

: Levels above 2.5 mEq/L Wisecracks [1] List 4 common clinical scenarios for Li toxicity and describe the clinical syndromes Acute toxicity a recent ingestion in a patient who is not therapeutically taking lithium. Acute toxicity typically manifests with gastrointestinal symptoms such as vomiting and diarrhea and can mimic many other disease states. Neurologic consequences of an acute lithium overdose (such as, altered mental status and seizures) occur several hours later after lithium redistributes (...) CRACKCast E160 – Lithium CRACKCast E160 – Lithium - CanadiEM CRACKCast E160 – Lithium In , by Adam Thomas March 19, 2018 This episode of CRACKCast covers Rosen’s Chapter 154, Lithium. You will have a solid approach to lithium overdose after listening to this episode! Shownotes – Rosen’s In Perspective : Lithium was approved for the treatment of bipolar disorder in 1970, and it remains one of the most effective agents for both depressive and manic symptoms. Lithium largely has no effect when

2018 CandiEM

8. CT-MRI LI-RADS v2017: A Comprehensive Guide for Beginners Full Text available with Trip Pro

CT-MRI LI-RADS v2017: A Comprehensive Guide for Beginners Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and the second leading cause of cancer-related deceases worldwide. Early diagnosis is essential for correct management and improvement of prognosis. Proposed for the first time in 2011 and updated for the last time in 2017, the Liver Imaging-Reporting and Data System (LI-RADS) is a comprehensive system for standardized interpretation and reporting of computed (...) tomography (CT) and magnetic resonance imaging (MRI) liver examinations, endorsed by the American College of Radiology to achieve congruence with HCC diagnostic criteria in at-risk populations. Understanding its algorithm is fundamental to correctly apply LI-RADS in clinical practice. In this pictorial review, we provide a guide for beginners, explaining LI-RADS indications, describing major and ancillary features and eventually elucidating the diagnostic algorithm with the use of some clinical examples.

2018 Journal of clinical and translational hepatology

9. Publishing in a heart failure journal—where lies the scientific interest? Full Text available with Trip Pro

Publishing in a heart failure journal—where lies the scientific interest? 29131547 2018 09 19 2018 11 13 2055-5822 4 4 2017 11 ESC heart failure ESC Heart Fail Publishing in a heart failure journal-where lies the scientific interest? 389-401 10.1002/ehf2.12233 Emami Amir A Department of Cardiology and Pneumology, University of Göttingen Medical Center, Robert-Koch-Strasse 40, D-37075, Göttingen, Germany. Ebner Nicole N Department of Cardiology and Pneumology, University of Göttingen Medical

2017 ESC heart failure

10. Autism spectrum disorder and Li-Fraumeni syndrome: purely coincidental or mechanistically associated? Full Text available with Trip Pro

Autism spectrum disorder and Li-Fraumeni syndrome: purely coincidental or mechanistically associated? Autism spectrum disorders (ASDs) are neurodevelopmental disorders with impaired social interactions and communication and restrictive, repetitive patterns of behaviors, interests, and activities. A recent epidemiological study suggests that children with ASD might have an increased cancer risk.The 14.5-year-old boy, previously diagnosed with ASD, was referred with persistent bone pain (...) . Diagnostic work-up confirmed diagnosis of acute lymphoblastic leukemia (ALL); cytogenetic analysis revealed low hypodiploid karyotype with a mutation (c.733G>A, p.Gly245Ser, rs28934575) in TP53 in the leukemic blasts. By Sanger sequencing, the presence of this mutation in the germline was subsequently confirmed and, thus, diagnosis of Li-Fraumeni syndrome (LFS) was made. His family history was remarkable with two siblings with intellectual disability and a mother who has died of premenopausal breast

2017 Molecular and cellular pediatrics

11. Changing views on child mortality and economic sanctions in Iraq: a history of lies, damned lies and statistics Full Text available with Trip Pro

Changing views on child mortality and economic sanctions in Iraq: a history of lies, damned lies and statistics In August 1990, Saddam Hussein's army invaded Kuwait and consequently the United Nations imposed economic sanctions on Iraq. In 1991, an international military alliance expelled the Iraqi army from Kuwait during a short war. Nevertheless, the economic sanctions remained in place-their removal required that Iraq should destroy its weapons of mass destruction. Subsequent years saw

2017 BMJ global health

12. Lithium Use in Pregnancy and the Risk of Cardiac Malformations. Full Text available with Trip Pro

Lithium Use in Pregnancy and the Risk of Cardiac Malformations. There has been concern that exposure to lithium early in pregnancy may be associated with a marked increase in the risk of Ebstein's anomaly (a right ventricular outflow tract obstruction defect) in infants and overall congenital cardiac defects, but data are conflicting and limited.We conducted a cohort study involving 1,325,563 pregnancies in women who were enrolled in Medicaid and who delivered a live-born infant between 2000 (...) and 2010. We examined the risk of cardiac malformations among infants exposed to lithium during the first trimester as compared with unexposed infants and, in secondary analyses, with infants exposed to another commonly used mood stabilizer, lamotrigine. Risk ratios and 95% confidence intervals were estimated with control for psychiatric and medical conditions, medications, and other potential confounders.Cardiac malformations were present in 16 of the 663 infants exposed to lithium (2.41%), 15,251

2017 NEJM

13. The progress of Chinese burn medicine from the Third Military Medical University—in memory of its pioneer, Professor Li Ao Full Text available with Trip Pro

The progress of Chinese burn medicine from the Third Military Medical University—in memory of its pioneer, Professor Li Ao Professor Li Ao was one of the founders of Chinese burn medicine and one of the most renowned doctors and researchers of burns in China. He established one of the Chinese earliest special departments for burns at Third Military Medical University (TMMU) in 1958. To memorialize Professor Li Ao on his 100th birthday in 2017 and introduce our extensive experience, it is our

2017 Burns & trauma

14. Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses

Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice (...) specialties and certifying boards Evidence Education * Associated Topics Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses Julie M. Coe, DDS, MS, MBA . Overview Systematic Review Conclusion Lithium disilicate (LD) single crowns indicated excellent outcome in 1 through 5 years (5-year cumulative survival, 97.8%) compared with LD fixed prostheses with only a fair outcome (5-year cumulative survival, 78.1

2017 ADA Center for Evidence-Based Dentistry

15. Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses

Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice (...) specialties and certifying boards Evidence Education * Associated Topics Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses Julie M. Coe, DDS, MS, MBA . Overview Systematic Review Conclusion Lithium disilicate (LD) single crowns indicated excellent outcome in 1 through 5 years (5-year cumulative survival, 97.8%) compared with LD fixed prostheses with only a fair outcome (5-year cumulative survival, 78.1

2017 ADA Center for Evidence-Based Dentistry

16. Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses

Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice (...) specialties and certifying boards Evidence Education * Associated Topics Lithium disilicate single crowns demonstrate favorable clinical outcomes in 1 through 5 years compared with lithium disilicate fixed prostheses Julie M. Coe, DDS, MS, MBA . Overview Systematic Review Conclusion Lithium disilicate (LD) single crowns indicated excellent outcome in 1 through 5 years (5-year cumulative survival, 97.8%) compared with LD fixed prostheses with only a fair outcome (5-year cumulative survival, 78.1

2017 ADA Center for Evidence-Based Dentistry

18. Organization of Chemotherapy and Systemic Therapy Services in India: The Devil Lies in the Details Full Text available with Trip Pro

Organization of Chemotherapy and Systemic Therapy Services in India: The Devil Lies in the Details 28717758 2019 01 13 2378-9506 3 2 2017 Apr Journal of global oncology J Glob Oncol Organization of Chemotherapy and Systemic Therapy Services in India: The Devil Lies in the Details. 182-183 10.1200/JGO.2016.006742 Rastogi Sameer S , All India Institute of Medical Sciences, New Delhi; , Fortis Noida, Uttar Pradesh, India. Aggarwal Aditi A , All India Institute of Medical Sciences, New Delhi

2016 Journal of global oncology

19. GADL1 variant and medication adherence in predicting response to lithium maintenance treatment in bipolar I disorder Full Text available with Trip Pro

GADL1 variant and medication adherence in predicting response to lithium maintenance treatment in bipolar I disorder Genetic variants and medication adherence have been identified to be the main factors contributing to lithium treatment response in bipolar disorders.To simultaneously examine effects of variant glutamate decarboxylase-like protein 1 (GADL1) and medication adherence on response to lithium maintenance treatment in Han Chinese patients with bipolar I (BPI) disorder.Frequencies (...) of manic and depressive episodes between carriers and non-carriers of the effective GADL1 rs17026688 T allele during the cumulative periods of off-lithium, poor adherence to lithium treatment and good adherence to lithium treatment were compared in Han Chinese patients with BPI disorder (n=215).GADL1 rs17026688 T carriers had significantly lower frequencies of recurrent affective episodes than non-T carriers during the cumulative period of good adherence, but not during those of poor adherence.GADL1

2016 BJPsych open

20. Use of lithium and cancer risk in patients with bipolar disorder: population-based cohort study Full Text available with Trip Pro

Use of lithium and cancer risk in patients with bipolar disorder: population-based cohort study Lithium inhibits glycogen synthase kinase-3, which is an enzyme involved in the pathogenesis of cancer.To investigate the association between lithium and cancer risk in patients with bipolar disorder.A retrospective cohort study was designed using the National Health Insurance Research Database (NHIRD) in Taiwan. Patients using lithium comprised the index drug group and patients using anticonvulsants (...) only comprised the control group. Time-dependent Cox regression was used to evaluate the hazard ratios (HRs) for risk of cancer.Compared with anticonvulsant-only exposure, lithium exposure was associated with significantly lower cancer risk (HR = 0.735, 95% CI 0.554-0.974). The hazard ratios for the first, second and third tertiles of the cumulative defined daily dose were 0.762 (95% CI 0.516-1.125), 0.919 (95% CI 0.640-1.318) and 0.552 (95% CI 0.367-0.831), respectively.Lithium is associated

2016 EvidenceUpdates