Latest & greatest articles for irritable bowel syndrome

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Top results for irritable bowel syndrome

41. Irritable bowel syndrome

Irritable bowel syndrome Evidence Maps - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2 (...) of known issues . Also read , explaining issues with the system. NOTE : Chrome is the best browser to use! To get started, type a condition/disease into the search box above. Here are some examples to get you started: Building Evidence Map X Axis Alphabetically Risk of bias No. Articles Sample Size Risk of bias any low Minimum sample size Apply Follow us: © 2019 Trip Database Ltd. company number 04316414. Trip is proud to be made in the UK.

2018 Trip Evidence Maps

42. Naturopathic approaches to irritable bowel syndrome: protocol for a prospective observational study in academic teaching clinics Full Text available with Trip Pro

Naturopathic approaches to irritable bowel syndrome: protocol for a prospective observational study in academic teaching clinics Irritable bowel syndrome (IBS) is a common functional bowel disorder with a worldwide prevalence estimated between 10% and 20%. It has a significant impact on quality of life and societal expense. While there are pharmaceutical options available, few can be reliably recommended. Many IBS sufferers turn to complementary and alternative medicine including naturopathy

2018 Integrative medicine research

43. IDDF2018-ABS-0047 Acupuncture and related therapies for treating irritable bowel syndrome: overview of systematic reviews and network meta-analysis Full Text available with Trip Pro

IDDF2018-ABS-0047 Acupuncture and related therapies for treating irritable bowel syndrome: overview of systematic reviews and network meta-analysis IDDF2018-ABS-0047 Acupuncture and related therapies for treating irritable bowel syndrome: overview of systematic reviews and network meta-analysis | Gut Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword (...) Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here IDDF2018-ABS-0047 Acupuncture and related therapies for treating irritable bowel syndrome: overview of systematic reviews and network meta-analysis Article Text Clinical Gastroenterology IDDF2018-ABS-0047 Acupuncture and related therapies for treating irritable bowel syndrome: overview of systematic reviews and network meta

2018 Clinical Gastroenterology

44. Eluxadoline (Viberzi) - irritable bowel syndrome with diarrhea (IBS-D)

Eluxadoline (Viberzi) - irritable bowel syndrome with diarrhea (IBS-D) Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity for SBDs written for approved

2018 Health Canada - Drug and Health Product Register

45. Efficacy, safety, and tolerability of plecanatide in patients with irritable bowel syndrome with constipation: results of two phase 3 randomized clinical trials (Abstract)

Efficacy, safety, and tolerability of plecanatide in patients with irritable bowel syndrome with constipation: results of two phase 3 randomized clinical trials Two identical, phase 3, randomized, double-blind, placebo-controlled trials evaluated the efficacy and safety of plecanatide in patients with irritable bowel syndrome with constipation (IBS-C).Adults meeting Rome III criteria for IBS-C were randomized (1:1:1) to placebo or plecanatide (3 or 6 mg) for 12 weeks. The primary efficacy end (...) point was the percentage of overall responders (patients reporting ≥30% reduction from baseline in worst abdominal pain plus an increase of ≥1 complete spontaneous bowel movement (CSBM)/week from baseline in the same week for ≥6 of 12 treatment weeks). Safety was assessed by adverse events (AEs).Overall, 2189 individuals were randomized across the two studies and 1879 completed the studies. Demographic and baseline characteristics were similar across treatment groups and between studies

2018 EvidenceUpdates

46. Irritable bowel syndrome

Irritable bowel syndrome Irritable bowel syndrome | Topics A to Z | CKS | NICE Search CKS… Menu Irritable bowel syndrome Irritable bowel syndrome Last revised in October 2017 Irritable bowel syndrome (IBS) is a chronic, relapsing, and often lifelong disorder of the lower gastrointestinal tract, with no structural cause Diagnosis Management Prescribing information Background information Irritable bowel syndrome: Summary Irritable bowel syndrome (IBS) is a chronic, relapsing, and often lifelong (...) disorder of the lower gastrointestinal tract, with no discernible structural or biochemical cause. Typical clinical features are abdominal pain: Associated with a change in stool form and/or frequency. Which may be related to defaecation, and there may be associated bloating. The exact underlying cause of IBS is unknown, but is likely to be multifactorial. The global prevalence of IBS in the general population is estimated to be 5–20%. The symptoms of IBS may fluctuate over years. A diagnosis of IBS

2018 NICE Clinical Knowledge Summaries

47. Irritable bowel syndrome

be individualised and is dependent on the patient's predominant symptoms. Definition Irritable bowel syndrome (IBS) is a chronic condition characterised by abdominal pain associated with bowel dysfunction. The pain is often relieved by defecation and is sometimes accompanied by abdominal bloating. There are no structural abnormalities to explain the pain. IBS occurs in about 15% of the adult population. The aetiology is probably multi-factorial and evidence suggests motility, inflammatory, genetic, immune (...) , psychological, and dietary components. Drossman DA, Camilleri M, Mayes FA. AGA technical review on irritable bowel syndrome. Gastroenterology. 2002 Dec;123(6):2108-31. http://www.ncbi.nlm.nih.gov/pubmed/12454866?tool=bestpractice.com History and exam presence of risk factors abdominal discomfort alteration of bowel habits associated with pain abdominal bloating or distension normal examination of abdomen passage of mucus with stool physical and sexual abuse age <50 years female sex previous enteric

2018 BMJ Best Practice

48. Viberzi - eluxadoline - Irritable bowel syndrome with diarrhea

and drug plans August 24, 2018 CDEC Final Recommendation posted August 29, 2018 Final CDR review report(s) and patient input posted September 18, 2018 Tags digestive system, gastrointestinal tract, diarrhea, irritable bowel syndrome, irritable bowel; Diarrhea Files Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter: (...) Viberzi - eluxadoline - Irritable bowel syndrome with diarrhea eluxadoline | CADTH.ca Find the information you need eluxadoline eluxadoline Last Updated: September 18, 2018 Result type: Reports Project Number: SR0560-000 Product Line: Generic Name: eluxadoline Brand Name: Viberzi Manufacturer: Allergan Pharma Co. Indications: Irritable bowel syndrome with diarrhea Manufacturer Requested Reimbursement Criteria 1 : As per the Health Canada-approved indication (for the tretment of irritable bowel

2018 Canadian Agency for Drugs and Technologies in Health - Common Drug Review

49. Self-Perception of Iranian Patients during their life with Irritable Bowel Syndrome: A Qualitative Study Full Text available with Trip Pro

Self-Perception of Iranian Patients during their life with Irritable Bowel Syndrome: A Qualitative Study Irritable bowel syndrome (IBS), as a chronic digestive disorder, impacts extensively on the quality of life, emotional well-being and self-identity. Chronic illness disrupts taken-for-granted notions about self. No qualitative study was found regarding patients' experience of life with irritable bowel syndrome (IBS) in Iran.To explore the self-perception of lived experience of IBS patients.A

2017 Electronic physician

50. A Diet Low in FODMAPs Reduces Symptoms in Patients With Irritable Bowel Syndrome and A Probiotic Restores Bifidobacterium Species: A Randomized Controlled Trial Full Text available with Trip Pro

A Diet Low in FODMAPs Reduces Symptoms in Patients With Irritable Bowel Syndrome and A Probiotic Restores Bifidobacterium Species: A Randomized Controlled Trial Dietary restriction of fermentable carbohydrates (a low FODMAP diet) has been reported to reduce symptoms in some patients with irritable bowel syndrome (IBS). We performed a randomized, placebo-controlled study to determine its effects on symptoms and the fecal microbiota in patients with IBS.We performed a 2×2 factorial trial of 104 (...) number of staple and non-staple foods as the low FODMAP diet; the diets had similar degrees of difficulty to follow. Dietary counselling was given to patients in all groups and data on foods eaten and compliance were collected. The incidence and severity of 15 gastrointestinal symptoms and overall symptoms were measured daily for 7 days before the study period; along with stool frequency and consistency. At baseline, global and individual symptoms were measured, along with generic and disease

2017 EvidenceUpdates

51. Eluxadoline for treating irritable bowel syndrome with diarrhoea

, having considered evidence on the nature of irritable bowel syndrome with diarrhoea (IBS-D) and the value placed on the benefits of eluxadoline by people with the condition, those who represent them, and clinical experts. It also took into account the effective use of NHS resources. Nature of the condition 4.2 The committee was aware of the experiences of people with IBS-D. It heard that IBS-D is diagnosed after physicians rule out other conditions, including inflammatory bowel disease, colorectal (...) it appropriate to stop. Eluxadoline for treating irritable bowel syndrome with diarrhoea (TA471) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 4 of 242 2 The technology The technology Description of Description of the technology the technology Eluxadoline (Truberzi, Allergan) is an opioid receptor agonist and delta-opioid receptor antagonist that binds to opioid receptors in the digestive system and slows down the movement

2017 National Institute for Health and Clinical Excellence - Technology Appraisals

52. Effects of a Low FODMAP Diet and Specific Carbohydrate Diet on Symptoms and Nutritional Adequacy of Patients with Irritable Bowel Syndrome: Preliminary Results of a Single-blinded Randomized Trial Full Text available with Trip Pro

Effects of a Low FODMAP Diet and Specific Carbohydrate Diet on Symptoms and Nutritional Adequacy of Patients with Irritable Bowel Syndrome: Preliminary Results of a Single-blinded Randomized Trial IBS is the most common functional disease of the low gastrointestinal tract. Recently, the interest towards a diet approach has increased, for example, a diet with low content of fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs). The aim of the present study

2017 Journal of translational internal medicine Controlled trial quality: uncertain

53. Irritable Bowel Syndrome. (Abstract)

Irritable Bowel Syndrome. This issue provides a clinical overview of irritable bowel syndrome, focusing on diagnosis, treatment, and practice improvement. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions

2017 Annals of Internal Medicine

54. Home-Based Hypnotherapy Self-exercises vs Individual Hypnotherapy With a Therapist for Treatment of Pediatric Irritable Bowel Syndrome, Functional Abdominal Pain, or Functional Abdominal Pain Syndrome: A Randomized Clinical Trial (Abstract)

Home-Based Hypnotherapy Self-exercises vs Individual Hypnotherapy With a Therapist for Treatment of Pediatric Irritable Bowel Syndrome, Functional Abdominal Pain, or Functional Abdominal Pain Syndrome: A Randomized Clinical Trial Individual gut-directed hypnotherapy (HT) is effective in pediatric irritable bowel syndrome (IBS) and functional abdominal pain or functional abdominal pain syndrome (FAP[S]). It is, however, unavailable to many children.To compare the effectiveness of HT by means

2017 EvidenceUpdates

55. Deciphering the pathophysiology of irritable bowel syndrome and functional gastrointestinal disorders—an alternative model for pathogenesis: cytokine controlled transepithelial multi-feedback loop Full Text available with Trip Pro

Deciphering the pathophysiology of irritable bowel syndrome and functional gastrointestinal disorders—an alternative model for pathogenesis: cytokine controlled transepithelial multi-feedback loop A working theoretical model for irritable bowel syndrome (IBS) and other functional gastrointestinal disorders (FGIDs) does not exist, hampered by the lack of any clear cut invention that address all symptom and signs of the disease. Reports of cessation of symptom and signs of both major types

2017 Translational gastroenterology and hepatology

56. The mind-body connection in irritable bowel syndrome: A randomised controlled trial of hypnotherapy as a treatment. Full Text available with Trip Pro

The mind-body connection in irritable bowel syndrome: A randomised controlled trial of hypnotherapy as a treatment. Hypnotherapy has been reported as being beneficial in the treatment of irritable bowel syndrome (IBS). We aimed to test the hypothesis that patients with IBS treated 'holistically' by hypnosis (i.e. by combined psychological and physiological symptom imagery) would have greater improvement in their IBS symptoms than patients treated by hypnosis using standard 'gut-directed (...) ' hypnotherapy, and both would be superior to simple relaxation therapy.Patients (n = 51) with Rome II criteria were randomised to 'individualised' (holistic) hypnotherapy, standard 'gut-directed' hypnotherapy or relaxation therapy for a period of 11 weeks with two follow-up assessments at 2 weeks and at 3 months after the completion of the trial. The primary outcome was bowel symptom severity scale (BSSS).All the participants in this study improved their IBS symptoms (pain, bloating, constipation

2017 Health psychology open Controlled trial quality: uncertain

57. The Effectiveness of Herbal Enema for Irritable Bowel Syndrome: A Meta-Analysis of Randomized, Calcium Channel Blocker-Controlled Trials Full Text available with Trip Pro

Channel Blocker-Controlled Trials DOI: KeyWord : Herbal enema, Irritable bowel syndrome, Meta-analysis Author Institution Chun-Yan Wang a a.Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Chinese Medicine, Shanghai, China Xu-Dong Tang bc b.Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing , China c.E-institute of Shanghai Municipal Education Commission, Shanghai University of Traditional Chinese Medicine, Shanghai , China Pei-Yong Zheng a a.Institute (...) Commission, Shanghai University of Traditional Chinese Medicine, Shanghai , China Hits : 1129 Download times : 1701 Abstract : Objective: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, and a symptom-based diagnosis. Because of the unclear mechanisms, the treatment available have not acquired the satisfied effect. We performed a meta-analysis to assess the effectiveness and safety of herbal enema in treating IBS compared to the calcium channel blocker administration

2017 World Journal of Traditional Chinese Medicine

58. Truberzi (eluxadoline) - for the treatment of adults who have irritable bowel syndrome with diarrhoea

index BSS Bristol Stool Scale CHMP Committee for Medicinal Products for Human Use Cmax maximum observed plasma concentration CNS central nervous system CSR clinical study report EMA European Medicines Agency EU European Union FDA US Food and Drug Administration GERD gastroesophageal reflux disease GI gastrointestinal IBS irritable bowel syndrome IBS-d diarrhea-predominant irritable bowel syndrome IBS-m irritable bowel syndrome, where a mixture of constipation and diarrhea is predominant IBS-QoL (...) discussion within the Committee, issued a positive opinion for granting a Marketing Authorisation to Truberzi. Assessment report EMA/549473/2016 Page 8/108 2. Scientific discussion 2.1. Introduction Problem statement Irritable Bowel Syndrome (IBS) is a chronic, relapsing gastrointestinal problem characterised primarily by intestinal pain and/or discomfort and associated alterations of defecation and/or bowel habit. Associations with other symptoms are regularly present, such as abdominal distension

2016 European Medicines Agency - EPARs

59. Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women Full Text available with Trip Pro

Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women Previous studies have indicated that serotonin-3-receptor antagonists might have a sex-specific effect in patients with irritable bowel syndrome with diarrhea (IBS-D). Alosetron has been approved for the treatment of only women, and ramosetron has been approved for the treatment for only men. We performed a randomized, placebo-controlled, phase 3 study to determine whether ramosetron (...) consistency (40.8%; 95% CI, 35.1%-46.6%) than in the placebo group (24.3%; 95% CI, 19.4%-29.7%)--a difference of 16.5% (95% CI, 8.9%-24.0%; P < .001). Patients receiving ramosetron had significant reductions in abdominal pain and discomfort (P = .001) and greater improvement in QOL (P = .002) compared with placebo. Ramosetron induced constipation in 11.0% of patients.In a randomized, placebo-controlled study of 576 women with IBS-D, 2.5 μg ramosetron per day reduced symptoms and increased stool

2016 EvidenceUpdates Controlled trial quality: predicted high

60. Underlying molecular and cellular mechanisms in childhood irritable bowel syndrome Full Text available with Trip Pro

Underlying molecular and cellular mechanisms in childhood irritable bowel syndrome Irritable bowel syndrome (IBS) affects a large number of children throughout the world. The symptom expression of IBS is heterogeneous, and several factors which may be interrelated within the IBS biopsychosocial model play a role. These factors include visceral hyperalgesia, intestinal permeability, gut microbiota, psychosocial distress, gut inflammation, bile acids, food intolerance, colonic bacterial

2016 Molecular and cellular pediatrics