Baloxavir marboxil (Xofluza) - influenza Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity for SBDs written for approved after September 1, 2012

Fever After Influenza, Diphtheria-Tetanus-Acellular Pertussis, and Pneumococcal Vaccinations Fever After Influenza, Diphtheria-Tetanus-Acellular Pertussis, and Pneumococcal Vaccinations - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine National Center for Biotechnology (...) Actions . 2020 Mar;145(3):e20191909. doi: 10.1542/peds.2019-1909. Epub 2020 Feb 6. Fever After Influenza, Diphtheria-Tetanus-Acellular Pertussis, and Pneumococcal Vaccinations , , , , , , , , Affiliations Expand Affiliations 1 Department of Pediatrics and walte002@mc.duke.edu. 2 Duke Human Vaccine Institute, School of Medicine, Duke University, Durham, North Carolina. 3 Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California, Oakland, California; and. 4 Immunization Safety Office

Do Corticosteroids Benefit Patients With Influenza Pneumonia? Do Corticosteroids Benefit Patients With Influenza Pneumonia? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page To read this article in full, please review your options for gaining access at the bottom of the page. Article in Press Do Corticosteroids Benefit Patients With Influenza Pneumonia? x Michael Gottlieb , MD (EBEM Commentator) , x Thomas Seagraves , MD (EBEM (...) Commentator) , x Stephen R. Gore , MD (EBEM Commentator) Department of Emergency Medicine, Rush University Medical Center, Chicago, IL DOI: Publication History Published online: July 23, 2019 To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Among patients with influenza pneumonia, corticosteroids are associated with increased mortality, longer length of stay in the ICU, and higher rates of secondary infection, although there are no data from

Avian influenza: guidance for managing human cases Avian influenza: guidance for managing human cases - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Avian influenza: guidance for managing human cases Information to assist with the management of possible and confirmed human (...) cases of avian influenza. Published 12 February 2014 Last updated 13 January 2020 — From: Documents Ref: PHE publications gateway number: GW-1025 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format

Avian influenza A(H5N6): risk assessment Avian influenza A(H5N6): risk assessment - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Avian influenza A(H5N6): risk assessment The risk to UK residents travelling to China is very low. This update includes information and advice (...) for travellers and clinicians. Published 15 February 2016 Last updated 8 January 2020 — From: Documents Ref: GW-997 HTML Details This update includes: background information risk assessment advice for travellers advice for clinicians The risk to UK residents travelling to China is very low. Published 15 February 2016 Last updated 8 January 2020 8 January 2020 Updated 'Avian influenza A(H5N6): risk assessment.' 17 April 2018 Updated 'Avian influenza A(H5N6): risk assessment.' 21 April 2017 Updated version

Cell-Mediated Immune Responses After Influenza Vaccination of Solid Organ Transplant Recipients: Secondary Outcomes Analyses of a Randomized Controlled Trial Cell-Mediated Immune Responses After Influenza Vaccination of Solid Organ Transplant Recipients: Secondary Outcomes Analyses of a Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go (...) your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Infect Dis Actions , 221 (1), 53-62 2020 Jan 1 Cell-Mediated Immune Responses After Influenza Vaccination of Solid Organ Transplant Recipients: Secondary Outcomes Analyses of a Randomized Controlled Trial

respiratory syndrome[MeSH Terms] #8 flu OR influenza OR grippe OR SARS OR “severe acute respiratory syndrome”[Text Word] #9 #7 OR #8 #10 #3 AND #6 AND #9 2.3 Study selection and data extraction Two reviewers independently screened the articles based on the titles, abstracts and full texts. Then, two reviewers independently exacted the following data from included studies: first author, publication year, country, disease, details of study population and intervention, study design, sample size, settings (...) and fit loosely to the user's face. 5,6 Although surgical masks cannot prevent inhalation of small airborne particles, both of them can protect users from large droplets and sprays. , There are conflicting recommendations for severe acute respiratory syndrome (SARS) and pandemic influenza: the World Health Organization (WHO) recommends using masks in low‐risk situations and respirators in high‐risk situations, but the Centers for Disease Control and Prevention (CDC) recommends using respirators

pandemics “Swine Flu” (CDC) estimated that 150, 000 to 575,000 people died from (H1N1) pandemic virus infection in the first year of the outbreak. 80% of the virus-related deaths were estimated to occur in those < 65 years of age. In seasonal influenza epidemics, about 70% to 90% of deaths occur in people ≥65. by the WHO: However, typical seasonal influenza causes most of its deaths among the elderly while other severe cases occur most commonly in people with a variety of medical conditions. By contrast (...) COVID-19 deaths compared with 'Swine Flu' COVID-19 deaths compared with “Swine Flu” - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website COVID-19 deaths compared with “Swine Flu” April 9, 2020 The age affected structure doesn’t fit with pandemic theory Carl Heneghan, Tom Jefferson “It is a capital mistake to theorize before one has data. Insensibly one begins to twist facts to suit theories, instead

COVID-19: Surge Triage for Suspected Influenza-Like Illness COVID-19: SURGE TRIAGE FOR SUSPECTED INFLUENZA-LIKE ILLNESS A Rapid Guidance Summary from the Penn Medicine Center for Evidence-based Practice Last updated March 29, 2020, 2:00 pm All links rechecked March 28 unless otherwise noted. Key questions answered in this summary • What options are available to help hospitals manage triage of patients with suspected COVID-19 infection? • How should patients be directed through triage when

materials to provide key audiences with information on seasonal influenza and encourage vaccination and the adoption of good hygiene practices. The toolkit guidance also includes suggested tactics for getting the message across to different audiences. Moreover, a logo has been created (‘Against the flu’) which can be used in conjunction with national initiatives at various events. Types of materials Prototype materials contained in this toolkit provide a hierarchy of information ranging from the concise (...) t the flu’ c an be tr an s l at ed into local languages. Posters The poster presents basic facts on influenza and key preventive messages which can be read and understood quickly. More detailed content can be made available to target audiences via factsheets and brochures but can also appear on websites and in other materials. Factsheets The tw o-p ag e f actsheets (1 30 x 2 50 mm) pr o v ide key information presented very synthetically. A lthough they c ont ain mor e t e xt th an the po s t er

for the flu season 2019 to 2020. 27 September 2018 Added new revised version of document. 8 August 2018 Added national influenza programme guidance for the inactivated influenza vaccine. 15 August 2017 Added link to slideset for the 2017 to 2018 national flu immunisation programme; for viewing and downloading. 7 August 2017 Revised guidance for the 2017 to 2018 flu season. 10 November 2016 Updated to include questions on air bubbles in pre-filled syringes and giving flu vaccine to patients taking oral (...) Inactivated influenza vaccine: information for healthcare practitioners Inactivated influenza vaccine: information for healthcare practitioners - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Inactivated

Seasonal influenza: managing cases in critical care units Seasonal influenza: managing cases in critical care units - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Seasonal influenza: managing cases (...) in critical care units Advice and recommendations for healthcare professionals on managing seasonal influenza cases in adult critical care units. Published 28 July 2017 Last updated 22 November 2019 — From: Documents Ref: PHE publications gateway number: GW-902 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. Details

Zanamivir (Dectova) - influenza A or B Published 09 December 2019 1 Product update SMC2204 zanamivir 10mg/mL solution for infusion (Dectova®) GlaxoSmithKline 9 August 2019 (Issued 8 November 2019) The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHSScotland. The advice is summarised as follows: ADVICE: following an abbreviated submission zanamivir (Dectova®) is accepted (...) for use within NHSScotland. Indication under review: Treatment of complicated and potentially life-threatening influenza A or B virus infection in adult and paediatric patients (aged = 6 months) when: ? the patient’s influenza virus is known or suspected to be resistant to anti-influenza medicinal products other than zanamivir, and/or ? other anti-viral medicinal products for treatment of influenza, including inhaled zanamivir, are not suitable for the individual patient. Zanamivir should be used

Point of care tests for influenza and other respiratory viruses Point of care tests for influenza and other respiratory viruses - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Register by 26 November to vote (...) in the General Election on 12 December. Guidance Point of care tests for influenza and other respiratory viruses Support for hospital trusts considering the introduction of point of care testing (POCT) for influenza and other respiratory viruses during winter 2019 to 2020. Published 27 November 2018 Last updated 28 October 2019 — From: Documents Ref: PHE publications gateway number: GW-846 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible

in the General Election on 12 December. Guidance Flu immunisation for early years settings including child minders Guidance for early years childcare settings on the nasal spray flu (influenza) vaccination for preschool children. Published 16 September 2016 Last updated 15 October 2019 — From: Documents Ref: PHE Publications Gateway Number 2019074 15 October 2019 Added pre-school guidance for the 2019 to 2020 flu season. 18 September 2018 Added revised guidance for early years childcare settings. 7 September (...) Flu immunisation for early years settings including child minders Flu immunisation for early years settings including child minders - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Register by 26 November to vote

Seasonal flu in the children and young people’s secure estate Seasonal flu in the children and young people’s secure estate - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Register by 26 November to vote in the General (...) Election on 12 December. Guidance Seasonal flu in the children and young people’s secure estate Guidance for healthcare and residential staff to help them respond to individual flu cases and manage outbreaks. Published 23 November 2017 Last updated 14 October 2019 — From: Documents Ref: PHE publications gateway number: GW-803 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need

Flu: information for prison and detention centre staff in England Flu: information for prison and detention centre staff in England - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Register by 26 November to vote (...) in the General Election on 12 December. Guidance Flu: information for prison and detention centre staff in England How to respond to individual cases or outbreaks of seasonal flu, including vaccination, recommendations and managing outbreaks. Published 1 October 2013 Last updated 14 October 2019 — From: Documents Ref: PHE publications gateway number GW-802 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us

Increasing Influenza and Pneumococcal Vaccination Uptake in Seniors Using Point-of-Care Informational Interventions in Primary Care in Singapore: A Pragmatic, Cluster-Randomized Crossover Trial Objectives. To evaluate the effectiveness of point-of-care informational interventions in general practitioner clinics to improve influenza and pneumococcal vaccination uptake among elderly patients.Methods. We conducted a pragmatic, cluster-randomized crossover trial in 22 private general practitioner (...) in the intervention and control periods, respectively. Both influenza (5.9% vs 4.8%; P = .047) and pneumococcal (5.7% vs 3.7%; P = .001) vaccination uptake rates were higher during the intervention period compared with the control period. On multilevel logistic regression analysis, follow-up for hypertension, diabetes mellitus, hyperlipidemia, or any combination of the 3 was associated with uptake of both vaccines.Conclusions. Point-of-care informational interventions likely contributed to increased influenza

Zanamivir (Dectova) - influenza Final Appraisal Recommendation Advice No: 1219 – October 2019 Zanamivir (Dectova ® ) 10 mg/ml solution for infusion Limited submission by GlaxoSmithKline UK This product is not currently marketed in the UK In reaching the above recommendation AWMSG has taken account of the appraisal documentation prepared by the AWMSG Secretariat (reference number 4130), which includes the AWMSG Secretariat Assessment Report (ASAR), the Preliminary Appraisal Recommendation (PAR (...) ) and the applicant company’s response to the PAR, clinical expert opinion (where available), the views of patients/patient carers (where available) and the lay member perspective. This recommendation has been ratified by Welsh Government and will be considered for review every three years. Recommendation of AWMSG Zanamivir (Dectova ® ) is recommended as an option for use within NHS Wales for the treatment of complicated and potentially life-threatening influenza A or B virus infection in adult and paediatric

of complications of influenza. Abbreviations: AAP — American Academy of Pediatrics ACIP — Advisory Committee on Immunization Practices CDC — Centers for Disease Control and Prevention CI — confidence interval FDA — US Food and Drug Administration GBS — Guillain-Barré syndrome HA — hemagglutinin HCP — health care personnel IDSA — Infectious Diseases Society of America IIV — inactivated influenza vaccine IIV3 — trivalent inactivated influenza vaccine IIV4 — quadrivalent inactivated influenza vaccine IV (...) that would notably impede vaccine delivery into the nasopharyngeal mucosa should have LAIV vaccination deferred until resolution. History of Guillain-Barré syndrome (GBS) after influenza vaccine is considered a precaution for the administration of influenza vaccines. Data on the risk of GBS after vaccination with seasonal influenza vaccine are variable and have been inconsistent across seasons. If there is an increased risk, it is likely small and primarily in adult patients. GBS is rare, especially