independent evaluation of 22 manual SARS- CoV-2 molecular tests (207) 201 Appendix E: RADTs undergoing independent evaluation by FIND as of 19 Sept 2020 (208) .. 208 Rapid HTA of alternatives to laboratory-based real-time RT-PCR to diagnose current infection with SARS-CoV-2 Health Information and Quality Authority viii Foreword The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious virus which has caused tens of millions of cases of COVID-19 since its emergence in 2019 (...) Rapid HTA of alternative tests to detect current infection with SARS-CoV-2 2 Rapid health technology assessment of xxxxx Health Information and Quality Authority Rapid health technology assessment (HTA) of alternatives to laboratory- based real-time RT-PCR to diagnose current infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Submitted to NPHET: 7 October 2020 Published: 21 October 2020 Rapid HTA of alternatives to laboratory-based real-time RT-PCR to diagnose current

ClearGuard HD Antimicrobial Barrier Cap for preventing haemodialysis catheter-related bloodstream infections ClearGuard HD Antimicrobial Barrier Cap for preventing haemodialysis catheter-related bloodstream infections Medtech innovation briefing Published: 3 November 2020 www.nice.org.uk/guidance/mib234 pathways Summary Summary • The technology technology described in this briefing is ClearGuard HD Antimicrobial Barrier Cap. It is a central venous catheter cap with chlorhexidine acetate coated (...) rod and cap threads, used to help prevent catheter-related bloodstream infections in people having haemodialysis. • The innovative aspects innovative aspects are that it could replace the need to clean the connector port with 2% chlorhexidine in 70% alcohol and potentially reduce the risk of catheter-related bloodstream infections. • The intended place in therapy place in therapy would be as an alternative to using standard central venous catheter caps in people having dialysis. • The main points

Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers and the risk of COVID-19 infection or severe disease: Systematic review and meta-analysis Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers and the risk of COVID-19 infection or severe disease: Systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other (...) Cardiol Heart Vasc Actions . 2020 Dec;31:100627. doi: 10.1016/j.ijcha.2020.100627. Epub 2020 Aug 27. Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers and the risk of COVID-19 infection or severe disease: Systematic review and meta-analysis , , , , , , , , Affiliations Expand Affiliations 1 Centro Cardiovascular da Universidade de Lisboa (CCUL), Faculdade de Medicina, Univerisdade de Lisboa, Avenida Professor Egas Moniz, 1649-028 Lisboa, Portugal. 2 Cardiology Department

Pharmacological therapies for patients with human coronavirus infections: a rapid systematic review Pharmacological therapies for patients with human coronavirus infections: a rapid systematic review - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health (...) therapies for patients with human coronavirus infections: a rapid systematic review [Article in En, Portuguese] , , , , , , , , , , Affiliations Expand Affiliations 1 Departamento de Ciência e Tecnologia, Ministério da Saúde, Brasília, DF, Brazil, keitty.andrade@saude.gov.br. 2 Departamento de Farmácia, Universidade de Brasilia, Brasília, DF, Brazil. PMID: 32876256 DOI: Free article Item in Clipboard Meta-Analysis Pharmacological therapies for patients with human coronavirus infections: a rapid

Is Preoperative Staphylococcus aureus Screening and Decolonization Effective at Reducing Surgical Site Infection in Patients Undergoing Orthopedic Surgery? A Systematic Review and Meta-Analysis With a Special Focus on Elective Total Joint Arthroplasty Is Preoperative Staphylococcus aureus Screening and Decolonization Effective at Reducing Surgical Site Infection in Patients Undergoing Orthopedic Surgery? A Systematic Review and Meta-Analysis With a Special Focus on Elective Total Joint (...) Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation J Arthroplasty Actions . 2020 Aug 14;S0883-5403(20)30893-7. doi: 10.1016/j.arth.2020.08.014. Online ahead of print. Is Preoperative Staphylococcus aureus Screening and Decolonization Effective at Reducing Surgical Site Infection in Patients Undergoing Orthopedic Surgery? A Systematic Review and Meta-Analysis With a Special Focus on Elective Total

Testing interventions for HIV and sexually transmitted infections (STIs) among young men who have sex with men Testing interventions for HIV and sexually transmitted infections (STIs) among young men who have sex with men | The Ontario HIV Treatment Network The Ontario HIV Treatment Network Testing interventions for HIV and sexually transmitted infections (STIs) among young men who have sex with men Testing interventions for HIV and sexually transmitted infections (STIs) among young men who (...) have sex with men , , , , , , , , , , , Questions What are effective interventions to increase uptake of HIV and sexually transmitted infections (STIs) testing among young men who have sex with men? Key take-home messages In Canada in 2018, 63% of all HIV diagnoses among youth were attributed to gay, bisexual, and other men who have sex with men (1); similarly, in the U.S. in 2018, 92% of HIV diagnoses among youth were attributed to male-to-male contact (2). In general, testing uptake for HIV (3, 4

Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find (...) Health NHS Trust, London, UK 6 Division of Neonatal–Perinatal Medicine, Dalhousie University IWK Health Centre, Halifax, NS, Canada 7 Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK 8 National Infection Service, Public Health England, London, UK 9 Centre for Reviews and Dissemination, University of York, York, UK 10 Bradford Neonatology, Bradford Royal Infirmary, Bradford, UK * Corresponding author Email: {{metadata.Journal}} Volume: {{metadata.Volume}}, Issue: {{metadata.Issue

Mortality Risk Assessment Using CHA(2)DS(2)-VASc Scores in Patients Hospitalized With Coronavirus Disease 2019 Infection Mortality Risk Assessment Using CHA(2)DS(2)-VASc Scores in Patients Hospitalized With Coronavirus Disease 2019 Infection - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving (...) of print. Mortality Risk Assessment Using CHA(2)DS(2)-VASc Scores in Patients Hospitalized With Coronavirus Disease 2019 Infection , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Cardiology Division, Regina Montis Regalis Hospital, Mondovì, Cuneo, Italy. 2 Baylor Heart and Vascular Institute, Dallas, Texas; Baylor University Medical Center, Dallas, Texas; Baylor Scott and White Heart and Vascular Hospital, Dallas, Texas. 3 Department of Clinical Internal, Anesthesiological

COVID-19: infection prevention and control (IPC) Wuhan novel coronavirus: infection prevention and control - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Wuhan novel coronavirus: infection prevention and control Guidance on infection prevention and control for Wuhan novel (...) coronavirus. Published 10 January 2020 Last updated 15 January 2020 — From: Documents HTML Details This guidance outlines infection control for healthcare providers assessing possible cases of WN-CoV. It should be used in conjunction with local policies. In the absence of effective drugs or a vaccine, control of this virus relies on the prompt identification, appropriate risk assessment, management and isolation of possible and confirmed cases, and the investigation and follow up of close contacts

Urinary tract infection: diagnostic tools for primary care Urinary tract infection: diagnostic tools for primary care - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search The United Kingdom is leaving the European Union on 31 October 2019. Guidance Urinary tract infection: diagnostic tools for primary care Quick reference materials for primary care on diagnosing and understanding culture results for urinary tract (...) infections (UTI). Published 21 November 2007 Last updated 6 September 2019 — From: Documents Ref: PHE publications gateway number: GW-673 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. Ref: PHE publications gateway number: GW-673 MS Word Document , 2.82MB This file may not be suitable for users of assistive technology

Primary Care Guidance for Persons With Human Immunodeficiency Virus: 2020 Update by the HIV Medicine Association of the Infectious Diseases Society of America Primary Care Guidance for Persons With Human Immunodeficiency Virus: 2020 Update by the HIV Medicine Association of the Infectious Diseases Society of America | Clinical Infectious Diseases | Oxford Academic ') We use cookies to enhance your experience on our website.By continuing to use our website, you are agreeing to our use of cookies (...) . You can change your cookie settings at any time. Advertisement Navbar Search Filter Mobile Microsite Search Term search filter search input Article Navigation Close mobile search navigation Article Navigation Article Contents Article Navigation Corrected proof Primary Care Guidance for Persons With Human Immunodeficiency Virus: 2020 Update by the HIV Medicine Association of the Infectious Diseases Society of America , Melanie A Thompson AIDS Research Consortium of Atlanta , Atlanta, Georgia, USA

infections caused by different SARS-CoV-2 viral strains. This can be accomplished with comparative genomic analyses, whereby polymorphisms in nucleotide sequences can provide evidence of differentiation between the viral strains. In addition to the number of polymorphisms, the elucidation of minority variants and rare mutations increase the probability that the viral strains are distinct. Strong evidence of reinfection also exists if sequences recovered from the two infectious events belong to different (...) to reinfection. Seroconversion for anti-SARS-CoV-2 IgG also supported the hypothesis that the second infection was SARS-CoV-2-related and not as a result of another infectious virus. As well as the published and pre-print studies discussed in this review, a website that is updated with potential SARS-CoV-2 reinfection cases was identified. (38) An additional seven cases of reinfection were listed (Appendix 4). Sources included news articles and personal communication between reporters and physicians

Pediatric hydrocephalus - Management of cerebrospinal fluid shunt infection 8. Management of cerebrospinal fluid shunt infection - cns.org ');//]]> × To support the neurosurgery community in these unprecedented times, the CNS is offering complimentary online education. . Reposted with permission from ©AANS, 2014 J Neurosurg Pediatrics (Suppl) 14: 60–71, 2014 AANS, 2014 (Original text of the guideline was edited to reflect the update. Please click for the original publication.) Pediatric (...) hydrocephalus: systematic literature review and evidence-based guidelines Part 8: Management of cerebrospinal fluid shunt infection UPDATE Mandeep S. Tamber, MD,1 Paul Klimo, Jr., MD, MPH,2,3 Catherine A. Mazzola, MD,4 Ann Marie Flannery, MD5 1 Department of Pediatric Neurological Surgery, Children’s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania; 2 Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, and 3 Le Bonheur Children’s Hospital, Memphis

distress rated (26.5%), neonatal asphyxia rated (1.4%). Only, 1.2% of neonates had apgar score < 7 at 5 min. Neonate admitted to ICU was rated 11.3%, while the rate of perinatal death was 2.2%. In the current review, none of the studies reported transmission of CoV from the mother to the fetus in utero during the study period. Conclusion: Coronavirus infection is more likely to affect pregnant women. Respiratory infectious diseases have demonstrated an increased risk of adverse maternal obstetrical (...) references Publication types Meta-Analysis Actions Systematic Review Actions MeSH terms Adolescent Actions Adult Actions Betacoronavirus / pathogenicity Actions Coronavirus Infections / diagnosis Actions Coronavirus Infections / transmission* Actions Female Actions Humans Actions Infectious Disease Transmission, Vertical* Actions Middle East Respiratory Syndrome Coronavirus / pathogenicity Actions Pandemics Actions Peptidyl-Dipeptidase A / metabolism Actions Pneumonia, Viral / diagnosis Actions Pneumonia

Meropenem/vaborbactam (Vaborem) - for the treatment of complicated urinary tract infection (cUTI) including acute pyelonephritis (AP), complicated intra-abdominal infection (cIAI), hospital-acquired pneumonia (HAP) including ventilator associated pneumoni Final Appraisal Recommendation Advice No: 1120 – October 2020 Meropenem/vaborbactam (Vaborem ® ) 1 g/1 g powder for concentrate for solution for infusion Submission by Menarini International Operations Luxembourg S.A. Recommendation of AWMSG (...) Meropenem/vaborbactam (Vaborem ® ) is recommended as an option for restricted use within NHS Wales. Meropenem/vaborbactam (Vaborem ® ) is licensed for the treatment of complicated urinary tract infection (cUTI) including acute pyelonephritis (AP), complicated intra-abdominal infection (cIAI), hospital-acquired pneumonia (HAP) including ventilator associated pneumonia (VAP) in adults; and for the treatment of patients with bacteraemia that occurs in association with, or is suspected to be associated

COVID-19: guidance for households with possible coronavirus infection COVID-19: guidance for households with possible coronavirus infection - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance and support Guidance COVID-19: guidance for households with possible coronavirus infection (...) Stay at home guidance for households with possible coronavirus (COVID-19) infection. Published 12 March 2020 Last updated 20 September 2020 — From: Documents HTML HTML Ref: PHE publications gateway number GW-1342 . Please tell us what format you need. It will help us if you say what assistive technology you use. . Please tell us what format you need. It will help us if you say what assistive technology you use. . Please tell us what format you need. It will help us if you say what assistive

A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections CRITICAL REVIEW FORM FOR A CLINICAL PREDICTION RULE Resident: Shane Leighton Date: 8/31/2020 Citation: Kupperman et al. A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections Pediatr 2019 Apr 1;173(4):342-351. Study Objective: To derive and validate a prediction rule to identify febrile infants less than 60 days (...) antibiotics in the past 48 hours, history of prematurity (less than or equal to 36 weeks gestation), pre-existing medical conditions, indwelling devices or sort tissue infections. •Outcome measures- SBI was defined as cystitis, bacteremia, or bacterial meningitis, where bacteremia and bacterial meningitis was defined as the growth of a single bacterial pathogen in blood or CSF, respectively. UTI was defined as growth of a single urine pathogen 1. At least 1,000 cfu/mL for cultures obtained by suprapubic

Guidance for contacts of people with confirmed coronavirus (COVID-19) infection who do not live with the person Guidance for contacts of people with confirmed coronavirus (COVID-19) infection who do not live with the person - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance (...) and support Guidance Guidance for contacts of people with confirmed coronavirus (COVID-19) infection who do not live with the person Guidance for contacts of a person with a positive test result for coronavirus (COVID-19) who do not live with that person. Published 28 May 2020 Last updated 17 June 2020 — From: Documents HTML Details This guidance is for people who have been notified by NHS Test and Trace that they are a contact of a person who has had a positive test result for coronavirus (COVID-19

use, patients should be thoroughly evaluated for the source of signs and symptoms before attributing them to the urinary tract. The presence of bacteria in the urine of catheterised patients is common and inevitable but ASB does not necessarily indicate presence of infection. 6 | Catheter-associated lower urinary tract infection in women35 Management of suspected bacterial lower urinary tract infection in adult women The following statements are reproduced, with permission, from The Infectious (...) Management of suspected bacterial lower urinary tract infection in adult women Management of suspected bacterial lower urinary tract infection in adult women A national clinical guideline September 2020 SIGN160Key to evidence statements and recommendations Levels of evidence 1 ++ High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias 1 + Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias 1 – Meta-analyses, systematic reviews

Coronavirus (COVID-19) infection and pregnancy 1 Information for healthcare professionals Version 12: Published Wednesday 14 October 2020 Coronavirus (COVID-19) Infection in Pregnancy2 Contents Summary of updates 3–5 1 Purpose and scope 6–12 2 Antenatal care during the COVID-19 pandemic 13–22 3 Venous thromboembolism prevention 23–25 4 Labour and birth during the COVID-19 pandemic 26–35 5 Managing clinical deterioration during the COVID-19 pandemic 36–42 6 Postnatal care 43–47 7 Acknowledgments (...) partners and other supportive adults has been published by the NHS, and should be followed as far as possible.5 12 14.10.20 4.6 Water birth: Supporting statement updated to reflect evidence review by the UK Infection Prevention and Control Cell. 12 14.10.20 6.3 Postnatal care: Recommendation revised to clarify that postnatal women who have tested positive for COVID-19, while required to isolate along with their households for 14 days, should still receive necessary in- person postnatal care. 12