Latest & greatest articles for hypothermia

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on hypothermia or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on hypothermia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for hypothermia

1. Therapeutic Hypothermia for Neonatal Encephalopathy

Therapeutic Hypothermia for Neonatal Encephalopathy Therapeutic Hypothermia for Neonatal Encephalopathy A Framework for Practice November 2020 Therapeutic Hypothermia for Neonatal Encephalopathy A BAPM Framework for Practice 2 ©BAPM 2020 Contents Executive summary 3 Members of the Working Group 4 Introduction 5 Case selection – eligibility 6 Notes on the practical application of TOBY criteria 6 Parent / carer communication 9 Infants who fall outside of current criteria 10 Infants identified (...) this document (*) – represents consensus view Therapeutic Hypothermia for Neonatal Encephalopathy A BAPM Framework for Practice 3 ©BAPM 2020 Executive summary Therapeutic hypothermia with intracorporeal temperature monitoring (TH) for moderate to severe neonatal encephalopathy (NE) is effective in improving outcomes and shows clear cost benefit. TH should be instigated in infants who have evidence suggesting significant perinatal hypoxia – ischaemia and significant neonatal encephalopathy on clinical

2021 British Association of Perinatal Medicine

2. Impact of Therapeutic Hypothermia During Cardiopulmonary Resuscitation on Neurologic Outcome: A Systematic Review and Meta-analysis Full Text available with Trip Pro

Impact of Therapeutic Hypothermia During Cardiopulmonary Resuscitation on Neurologic Outcome: A Systematic Review and Meta-analysis Impact of Therapeutic Hypothermia During Cardiopulmonary Resuscitation on Neurologic Outcome: A Systematic Review and Meta-analysis | Research Square Browse Tools & Services Your Cart This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints (...) . The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice. Research Impact of Therapeutic Hypothermia During Cardiopulmonary Resuscitation on Neurologic Outcome: A Systematic Review and Meta-analysis Filippo Annoni, Lorenzo PELUSO, Marco FIORE, Per NORDBERG, Leif SVENSSON, Benjamin ABELLA, Lorenzo CALABRO', Sabino SCOLLETTA, Jean-Louis VINCENT, Jacques CRETEUR, Fabio

2020 Research Square

3. Meta-Analysis of the Usefulness of Therapeutic Hypothermia After Cardiac Arrest

Meta-Analysis of the Usefulness of Therapeutic Hypothermia After Cardiac Arrest Meta-Analysis of the Usefulness of Therapeutic Hypothermia After Cardiac Arrest - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC: . Get the latest (...) new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Am J Cardiol Actions . 2020 Jul 24;S0002-9149(20)30772-4. doi: 10.1016/j.amjcard.2020.07.038. Online ahead of print. Meta-Analysis of the Usefulness of Therapeutic Hypothermia After Cardiac Arrest

2020 EvidenceUpdates

4. Therapeutic Hypothermia in Critically Ill Patients: A Systematic Review and Meta-Analysis of High Quality Randomized Trials

Therapeutic Hypothermia in Critically Ill Patients: A Systematic Review and Meta-Analysis of High Quality Randomized Trials Therapeutic Hypothermia in Critically Ill Patients: A Systematic Review and Meta-Analysis of High Quality Randomized Trials - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health (...) Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Crit Care Med Actions . 2020 Jul;48(7):1047-1054. doi: 10.1097/CCM.0000000000004364. Therapeutic Hypothermia in Critically Ill Patients: A Systematic Review and Meta-Analysis of High Quality Randomized Trials , , , , , , , Affiliations Expand Affiliations 1 Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy. 2 Vita-Salute San Raffaele

2020 EvidenceUpdates

5. Prevention of Perioperative Hypothermia: A Prospective, Randomized, Controlled Trial of Bair Hugger Versus Inditherm in Patients Undergoing Elective Arthroscopic Shoulder Surgery

Prevention of Perioperative Hypothermia: A Prospective, Randomized, Controlled Trial of Bair Hugger Versus Inditherm in Patients Undergoing Elective Arthroscopic Shoulder Surgery Prevention of Perioperative Hypothermia: A Prospective, Randomized, Controlled Trial of Bair Hugger Versus Inditherm in Patients Undergoing Elective Arthroscopic Shoulder Surgery - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search (...) : Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Arthroscopy Actions . 2020 Feb;36(2):347-352. doi: 10.1016/j.arthro.2019.08.015. Epub 2019 Dec 31. Prevention of Perioperative Hypothermia: A Prospective, Randomized, Controlled Trial of Bair Hugger Versus Inditherm in Patients Undergoing Elective Arthroscopic Shoulder Surgery , , , , , , , Affiliations Expand Affiliations 1 The Royal Liverpool & Broadgreen

2020 EvidenceUpdates

6. Methodological quality of systematic reviews addressing therapeutic hypothermia and/or cooling therapy for traumatic brain injury Full Text available with Trip Pro

Methodological quality of systematic reviews addressing therapeutic hypothermia and/or cooling therapy for traumatic brain injury 996 Methodological quality of systematic reviews addressing therapeutic hypothermia and/or cooling therapy for traumatic brain injury Carolina Oliveira Cruz Latorraca* Raphael Einsfeld Simões Ferreira** Bernardo Lembo Conde de Paiva*** Ricardo Silva Centeno* Ana Luiza Cabrera Martimbianco** Rachel Riera**** Rafael Leite Pacheco** Abstract Therapeutic hypothermia (...) and/or cooling therapy are suggested to have benefits in patients with acute traumatic brain injury, and several systematic reviews (SRs) have been performed to synthesize the evidence from randomized clinical trials (RCTs). The objective of this critical appraisal study was to assess the methodological quality of SRs that evaluated the use of therapeutic hypothermia and/or cooling therapy in patients with acute traumatic brain injury. A broad and sensitive search of the literature was performed in March

2019 O Mundo da Saúde

7. Neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis Full Text available with Trip Pro

Neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis Neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis | Research Square Browse Tools & Services Your Cart This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should (...) not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice. Research article Neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis Biruk Abate Beletew, Ayelign Mengesha Kasie, Mesfin Wudu Kassaw, Melese Abate Reta Biruk Abate Beletew Woldia University Corresponding Author ORCiD: https://orcid.org/0000-0003-0833-2504 Ayelign Mengesha Kasie Woldia University Mesfin Wudu Kassaw

2019 Research Square

8. A Randomized Controlled Study of Low-Dose Hydrocortisone Versus Placebo in Dopamine-Treated Hypotensive Neonates Undergoing Hypothermia Treatment for Hypoxic-Ischemic Encephalopathy (Abstract)

A Randomized Controlled Study of Low-Dose Hydrocortisone Versus Placebo in Dopamine-Treated Hypotensive Neonates Undergoing Hypothermia Treatment for Hypoxic-Ischemic Encephalopathy To investigate whether hydrocortisone supplementation increases blood pressure and decreases inotrope requirements compared with placebo in cooled, asphyxiated neonates with volume-resistant hypotension.A double-blind, randomized, placebo-controlled clinical trial was conducted in a Level III neonatal intensive care (...) and 3.3 μg/dL, P = .87; respectively), suggesting inappropriate adrenal function. Short-term clinical outcomes were similar in the 2 groups.Hydrocortisone administration was effective in raising the blood pressure and decreasing inotrope requirement in asphyxiated neonates with volume-resistant hypotension during hypothermia treatment.ClinicalTrials.gov: NCT02700828.Copyright © 2019 Elsevier Inc. All rights reserved.

2019 EvidenceUpdates

9. Hypothermia outcome prediction after extracorporeal life support for hypothermic cardiac arrest patients: An external validation of the HOPE score Full Text available with Trip Pro

Hypothermia outcome prediction after extracorporeal life support for hypothermic cardiac arrest patients: An external validation of the HOPE score The HOPE score, based on covariates available at hospital admission, predicts the probability of in-hospital survival after extracorporeal life support (ECLS) rewarming of a given hypothermic cardiac arrest patient with accidental hypothermia. Our goal was to externally validate the HOPE score.We included consecutive hypothermic arrested patients who (...) underwent rewarming with ECLS. The sample comprised 122 patients. The six independent predictors of survival included in the HOPE score were collected for each patient: age, sex, mechanism of hypothermia, core temperature at admission, serum potassium level at admission and duration of CPR. The primary outcome parameter was survival to hospital discharge.Overall, 51 of the 122 included patients survived, resulting in an empirical (global) probability of survival of 42% (95% CI = [33-51

2019 EvidenceUpdates

10. Therapeutic hypothermia for acute ischaemic stroke

Therapeutic hypothermia for acute ischaemic stroke Ther Therapeutic h apeutic hypothermia for acute ischaemic ypothermia for acute ischaemic strok stroke e Interventional procedures guidance Published: 29 May 2019 www.nice.org.uk/guidance/ipg647 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take this guidance fully (...) . Nothing in this guidance should be interpreted in a way that would be inconsistent with compliance with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. 1 1 Recommendations Recommendations 1.1 Current evidence on the safety of therapeutic hypothermia for acute ischaemic stroke shows that there are serious

2019 National Institute for Health and Clinical Excellence - Interventional Procedures

11. Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction Full Text available with Trip Pro

Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction Experimental trials suggest improved outcome by mild therapeutic hypothermia for cardiogenic shock after acute myocardial infarction. The objective of this study was to investigate the hemodynamic effects of mild therapeutic hypothermia in patients with cardiogenic shock complicating acute myocardial infarction.Patients (n=40) with cardiogenic shock undergoing primary percutaneous coronary intervention without classic (...) indications for mild therapeutic hypothermia underwent randomization in a 1:1 fashion to mild therapeutic hypothermia for 24 hours or control. The primary end point was cardiac power index at 24 hours; secondary end points included other hemodynamic parameters and serial measurements of arterial lactate.No relevant differences were observed for the primary end point of cardiac power index at 24 hours (mild therapeutic hypothermia versus control: 0.41 [interquartile range, 0.31-0.52] versus 0.36

2019 EvidenceUpdates

12. Induced hypothermia is associated with reduced circulating subunits of mitochondrial DNA in cardiac arrest patients. Full Text available with Trip Pro

Induced hypothermia is associated with reduced circulating subunits of mitochondrial DNA in cardiac arrest patients. Induced hypothermia may protect from ischemia reperfusion injury. The mechanism of protection is not fully understood and may include an effect on mitochondria. Here we describe the effect of hypothermia on circulating mitochondrial (mt) DNA in a substudy of a multicenter randomized trial (the Target Temperature Management trial). Circulating levels of mtDNA were elevated

2019 Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis Controlled trial quality: uncertain

13. Thermal Suit or Forced Air Warming in Prevention of Perioperative Hypothermia: A Randomized Controlled Trial. (Abstract)

Thermal Suit or Forced Air Warming in Prevention of Perioperative Hypothermia: A Randomized Controlled Trial. To prevent perioperative hypothermia, forced air warming blanket was compared with a passive insulation suit.Prospective, open, randomized controlled trial.Thirty patients were scheduled for orthopedic spinal surgery. The intervention group (group TS) received the thermal suit T-Balance before premedication and throughout the perioperative period, whereas the control group (group C (...) ) received forced air warming (FAW) during surgery.No statistically significant difference (ns) was found between the groups for core temperature 30 minutes after induction of general anesthesia. Perioperative hypothermia occurred in 10 (66.7%) patients in group TS and 6 (40%) in group C (ns). For hypothermic patients, re-establishment of normothermia took significantly longer in group TS, mean 108 ± 111 minutes, than in group C, 33 ± 59.5 minutes (P = .03).The thermal suit did not prevent hypothermia

2019 Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses Controlled trial quality: uncertain

14. Therapeutic hypothermia after paediatric cardiac arrest: Pooled randomized controlled trials Full Text available with Trip Pro

Therapeutic hypothermia after paediatric cardiac arrest: Pooled randomized controlled trials Separate trials to evaluate therapeutic hypothermia after paediatric cardiac arrest for out-of-hospital and in-hospital settings reported no statistically significant differences in survival with favourable neurobehavioral outcome or safety compared to therapeutic normothermia. However, larger sample sizes might detect smaller clinical effects. Our aim was to pool data from identically conducted trials (...) to approximately double the sample size of the individual trials yielding greater statistical power to compare outcomes.Combine individual patient data from two clinical trials set in forty-one paediatric intensive care units in USA, Canada and UK. Children aged at least 48 h up to 18 years old, who remained comatose after resuscitation, were randomized within 6 h of return of circulation to hypothermia or normothermia (target 33.0 °C or 36.8 °C). The primary outcome, survival 12 months post-arrest

2018 EvidenceUpdates

15. Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial. Full Text available with Trip Pro

Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial. After severe traumatic brain injury, induction of prophylactic hypothermia has been suggested to be neuroprotective and improve long-term neurologic outcomes.To determine the effectiveness of early prophylactic hypothermia compared with normothermic management of patients after severe traumatic brain injury.The Prophylactic Hypothermia (...) Trial to Lessen Traumatic Brain Injury-Randomized Clinical Trial (POLAR-RCT) was a multicenter randomized trial in 6 countries that recruited 511 patients both out-of-hospital and in emergency departments after severe traumatic brain injury. The first patient was enrolled on December 5, 2010, and the last on November 10, 2017. The final date of follow-up was May 15, 2018.There were 266 patients randomized to the prophylactic hypothermia group and 245 to normothermic management. Prophylactic

2018 JAMA Controlled trial quality: predicted high

16. Xenon as an adjuvant to therapeutic hypothermia in near-term and term newborns with hypoxic-ischaemic encephalopathy. Full Text available with Trip Pro

Xenon as an adjuvant to therapeutic hypothermia in near-term and term newborns with hypoxic-ischaemic encephalopathy. Hypoxic-ischaemic encephalopathy (HIE) is a serious birth complication affecting term and late preterm newborns. Although therapeutic hypothermia (cooling) has been shown to be an effective therapy for neonatal HIE, many cooled infants have poor long-term neurodevelopmental outcomes. In animal models of neonatal encephalopathy, inhaled xenon combined with cooling has been shown (...) to offer better neuroprotection than cooling alone.To determine the effects of xenon as an adjuvant to therapeutic hypothermia on mortality and neurodevelopmental morbidity, and to ascertain clinically important side effects of xenon plus therapeutic hypothermia in newborn infants with HIE. To assess early predictors of adverse outcomes and potential side effects of xenon.We used the standard strategy of the Cochrane Neonatal Review Group to search the Cochrane Library (2017, Issue 8), MEDLINE (from

2018 Cochrane

17. Hypothermia

Hypothermia Top results for hypothermia - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for hypothermia The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

18. Effect of preoperative warming on intraoperative hypothermia: a randomized-controlled trial Full Text available with Trip Pro

Effect of preoperative warming on intraoperative hypothermia: a randomized-controlled trial The purpose of this study was to evaluate the effects of preoperative forced-air warming on intraoperative hypothermia.In this randomized-controlled trial, adult patients scheduled for elective, non-cardiac surgery under general anesthesia were stratified by scheduled surgical duration (< 2.5 hr or ≥ 2.5 hr) and then randomized to a pre-warming group using a BairPaws™ forced-air warming system (...) for at least 30 min preoperatively or to a control group with warmed blankets on request. All patients were warmed intraoperatively via convective forced-air warming blankets. Perioperative temperature was measured using the SpotOn™ temperature system consisting of a single-use disposable sensor applied to the participant's forehead. The primary outcome was the magnitude of intraoperative hypothermia calculated as the area under the time-temperature curve for core temperatures < 36°C between induction

2018 EvidenceUpdates

19. Hypothermia for newborns with hypoxic-ischemic encephalopathy

Hypothermia for newborns with hypoxic-ischemic encephalopathy Therapeutic hypothermia is a standard of care for infants ≥36 weeks gestational age (GA) with moderate-to-severe hypoxic-ischemic encephalopathy. Because some studies included infants born at 35 weeks GA, hypothermia should be considered if they meet other criteria. Cooling for infants <35 weeks GA is not recommended. Passive cooling should be started promptly in community centres, in consultation with a tertiary care centre (...) image (MRI) is advised shortly after rewarming and, in cases where earlier findings do not match the clinical picture, a repeat MRI after 10 days of life is suggested. Multidisciplinary neurodevelopmental follow-up is recommended. Keywords: Hypoxic-ischemic encephalopathy; Therapeutic hypothermia

2018 Canadian Paediatric Society

20. Flowchart: Hypoxic-ischaemic encephalopathy, Checklist for therapeutic hypothermia (cooling)

Flowchart: Hypoxic-ischaemic encephalopathy, Checklist for therapeutic hypothermia (cooling) Queensland Health State of Queensland (Queensland Health) 2018 http://creativecommons.org/licenses/by-nc-nd/3.0/au/deed.en Queensland Clinical Guidelines, Guidelines@health.qld.gov.au Queensland Clinical Guidelines www.health.qld.gov.au/qcg Checklist for therapeutic hypothermia If baby has a perinatal event and/or acidosis and meets the criteria below, therapeutic hypothermia may be indicated. Call (...) Retrieval Services Queensland immediately on 1300 799 127 to discuss the need for transfer and therapeutic hypothermia with a neonatologist. Therapeutic hypothermia criteria ? Evidence of acidosis or depression at birth, as indicated by at least one of the following: ? Apgar score = 5 at 10 minutes ? pH < 7.00 or a base excess equal to or worse than minus 12 mmol/L on a cord/arterial/venous/capillary blood gas obtained within 60 minutes of birth ? Mechanical ventilation or ongoing resuscitation for = 10

2018 Queensland Health