Use of an electronic decision support tool to reduce polypharmacy in elderly people with chronic diseases: cluster randomised controlled trial. To evaluate the effects of a computerised decision support tool for comprehensive drug review in elderly people with polypharmacy.Pragmatic, multicentre, cluster randomised controlled trial.359 general practices in Austria, Germany, Italy, and the United Kingdom.3904 adults aged 75 years and older using eight or more drugs on a regular basis, recruited (...) -0.63 to -0.26; P<0.001).In intention-to-treat analysis, a computerised decision support tool for comprehensive drug review of elderly people with polypharmacy showed no conclusive effects on the composite of unplanned hospital admission or death by 24 months. Nonetheless, a reduction in drugs was achieved without detriment to patient outcomes.Current Controlled Trials ISRCTN10137559.© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights

Rapid POC tests have low sensitivity for C trachomatis in nonpregnant women or men of reproductive age. Grillo-Ardila CF, Torres M, Gaitan HG. Rapid point of care test for detecting urogenital Chlamydia trachomatis infection in nonpregnant women and men at reproductive age. Cochrane Database Syst Rev. 2020;1:CD011708. 31995238.

In older adults with a history of falls, interventions to reduce use of fall risk-increasing drugs do not reduce falls. Hart LA, Phelan EA, Yi JY, Marcum ZA, Gray SL. Use of fall risk-increasing drugs around a fall-related injury in older adults: a systematic review. J Am Geriatr Soc. 2020. [Epub ahead of print]. 32064594.

with the standard BGM group (adjusted group difference, -0.3%; 95% CI, -0.4% to -0.1%; P <.001). The most commonly reported adverse events using CGM and standard BGM, respectively, were severe hypoglycemia (1 and 10), fractures (5 and 1), falls (4 and 3), and emergency department visits (6 and 8).Among adults aged 60 years or older with type 1 diabetes, continuous glucose monitoring compared with standard blood glucose monitoring resulted in a small but statistically significant improvement in hypoglycemia over (...) Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults With Type 1 Diabetes: A Randomized Clinical Trial. Continuous glucose monitoring (CGM) provides real-time assessment of glucose levels and may be beneficial in reducing hypoglycemia in older adults with type 1 diabetes.To determine whether CGM is effective in reducing hypoglycemia compared with standard blood glucose monitoring (BGM) in older adults with type 1 diabetes.Randomized clinical trial conducted at 22

Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults. Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD), yet much of COPD risk remains unexplained.To determine whether dysanapsis, a mismatch of airway tree caliber to lung size, assessed by computed tomography (CT), is associated with incident COPD among older adults and lung function decline in COPD.A retrospective cohort study of 2 community-based samples: the Multi-Ethnic Study (...) ] age, 69 years [9 years]; 1334 women [52.7%]), 237 of 2531 participants (9.4%) had prevalent COPD, the mean (SD) airway to lung ratio was 0.033 (0.004), and the mean (SD) FEV1 decline was -33 mL/y (31 mL/y). Of 2294 MESA Lung participants without prevalent COPD, 98 (4.3%) had incident COPD at a median of 6.2 years. Compared with participants in the highest quartile of airway to lung ratio, those in the lowest had a significantly higher COPD incidence (9.8 vs 1.2 cases per 1000 person-years; rate

-controlled trial TRUST (Thyroid Hormone Replacement for Untreated Older Adults with Subclinical Hypothyroidism Trial). (ClinicalTrials.gov: NCT01660126).Switzerland, Ireland, the Netherlands, and Scotland.638 persons aged 65 years or older with persistent SCH (thyroid-stimulating hormone level of 4.60 to 19.9 mIU/L for >3 months and normal free thyroxine level) and complete outcome data.L-thyroxine or matching placebo with mock dose titration.1-year change in Hypothyroid Symptoms and Tiredness scores (...) L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial. L-thyroxine does not improve hypothyroid symptoms among adults with subclinical hypothyroidism (SCH). However, those with greater symptom burden before treatment may still benefit.To determine whether L-thyroxine improves hypothyroid symptoms and tiredness among older adults with SCH and greater symptom burden.Secondary analysis of the randomized, placebo

COVID-19: End of life care in older people COVID-19: End of life care in older people | British Geriatrics Society Toggle main menu visibility Search Search Search Resources (menu position rule) , , Date Published: 07 April 2020 Last updated: 08 June 2020 This page brings together resources and information for any clinician or carer who finds themselves faced with providing care at the end of life during the COVID-19 pandemic. COVID-19 has moved death and dying to the centre stage. While end (...) of life care has always been an integral part of care for older people, the acute and rapid nature of COVID-19 changes the pace and focus of that care. Clinicians and carers will need to give both the best physical care possible and also provide the human contact and comfort to older people who are dying - ideally provided by those they love. Person-centred care has never been more necessary, including sensitive advance care planning conversations and best interest decisions -communicated clearly

: Item in Clipboard Full-text links Cite Abstract Background: It remains unclear whether volar locked plating (VLP) yields a better functional outcome than closed reduction and casting (CRC) for elderly patients with an acute, displaced distal radial fracture. Our purpose was to conduct a systematic review and meta-analysis of randomized controlled trials comparing outcomes of VLP and CRC for elderly patients (age, ≥60 years). Methods: Multiple databases, including MEDLINE, were searched (...) for randomized controlled trials evaluating outcomes following distal radial fracture treatment. Raw data were obtained for studies that included patients of all ages, and the elderly subgroup was included for analysis. The primary outcome was the Disabilities of the Arm, Shoulder and Hand (DASH) score at ≥1 year of follow-up. Secondary outcomes included the 3-month DASH score, range of motion, final radiographic alignment, and complications. Effect sizes for the comparison of each outcome between groups

older persons with mild cognitive impairment (aged 60-83) were randomly allocated to three intervention groups and one waitlist control group. Interventions: The physical training, cognitive training, and combined physical and cognitive training intervention programs were delivered for 60 to 90 minutes, one to three times per week for 12 weeks with six-month follow-up. Main measures: Participants were assessed at baseline, 12 weeks after baseline, and 36 weeks after baseline for fall incidence (...) Effects of combined physical and cognitive training on fall prevention and risk reduction in older persons with mild cognitive impairment: a randomized controlled study Effects of Combined Physical and Cognitive Training on Fall Prevention and Risk Reduction in Older Persons With Mild Cognitive Impairment: A Randomized Controlled Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several

Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old Comparison of Efficacy Nebulized Fentanyl With Intravenous Ketorolac for Renal Colic in Patients Over 12 Years Old - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library (...) displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Am J Emerg Med Actions . 2020 Apr 21;S0735-6757(20)30257-6. doi: 10.1016/j.ajem.2020.04.053. Online ahead of print. Comparison of Efficacy Nebulized Fentanyl With Intravenous Ketorolac for Renal Colic in Patients Over 12 Years Old , , , Affiliations Expand Affiliations 1 Clinical Research Development Center of Taleghani, Kermanshah University of Medical Sciences, Kermanshah, Iran. 2 Department of Emergency

predictive ability. Conclusions: We developed a dynamic prediction model that was able to update predictions of the risk of death as updated measurements of FI became available. This model could be used to estimate the risk of death in individuals aged >65 years. Keywords: dynamic statistical prediction model; frailty index; older people; people over 65 years; prospective cohort study; risk of death. © The Author(s) 2020. Published by Oxford University Press on behalf of the British Geriatrics Society (...) a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Age Ageing Actions . 2020 May 4;afaa056. doi: 10.1093/ageing/afaa056. Online ahead of print. Dynamic Statistical Model for Predicting the Risk of Death Among Older Chinese People, Using Longitudinal Repeated Measures of the Frailty Index: A Prospective Cohort Study , , , , , , , , , Affiliations

) after the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to quantify the 90-day risk of AKI in older adults after initiation of SGLT2 inhibitors in routine clinical practice. Methods: We conducted a population-based retrospective cohort study in Ontario, Canada, involving adults with diabetes who were aged 66 years or older and who were newly dispensed either an SGLT2 inhibitor or a dipeptidyl peptidase-4 (DPP4) inhibitor in an outpatient setting between 2015 (...) Use of sodium-glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study Use of Sodium-Glucose cotransporter-2 Inhibitors and Risk of Acute Kidney Injury in Older Adults With Diabetes: A Population-Based Cohort Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily

links Cite Erratum in Am J Psychiatry. 2020 Jun 1;177(6):556. doi: 10.1176/appi.ajp.2020.1776correction. Am J Psychiatry. 2020. PMID: 32475135 No abstract available. Abstract Objective: Age-related cognitive decline, the deterioration in functions such as memory and executive function, is faced by most older adults and affects function and quality of life. No approved treatments exist for age-related cognitive decline. Computerized cognitive training has been shown to provide consistent albeit (...) modest improvements in cognitive function as measured by neuropsychological testing. Vortioxetine, an antidepressant medication, has putative procognitive and proneuroplastic properties and therefore may be able to augment cognitive training. In this placebo-controlled study, the authors tested the cognitive benefits of vortioxetine added to cognitive training for adults age 65 or older with age-related cognitive decline. Methods: After a 2-week lead-in period of cognitive training, 100 participants

interdisciplinary home rehabilitation for older people with hip fracture on independence in activities of daily living (ADL) compared with inhospital geriatric care according to a multifactorial rehabilitation program. Design: Planned analysis of a randomized controlled trial with 3- and 12-month follow-ups. Setting: Geriatric ward, ordinary housing, and residential care facilities. Participants: Of 466 people screened for eligibility, participants (N=205) with acute hip fracture, aged 70 years or older (...) Effects of Geriatric Interdisciplinary Home Rehabilitation on Independence in Activities of Daily Living in Older People With Hip Fracture: A Randomized Controlled Trial Effects of Geriatric Interdisciplinary Home Rehabilitation on Independence in Activities of Daily Living in Older People With Hip Fracture: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History

Sciences, University of Southampton, Southampton, UK. 2 Department Care I, Musculoskeletal System & Neurology, Dutch National Health Care Institute, Diemen, The Netherlands. 3 EULAR Standing Committee of People with Arthritis/Rheumatism in Europe (PARE), Zurich, Switzerland. 4 EULAR Young PARE, Zurich, Switzerland. 5 Slovak League Against Rheumatism, Piestany, Slovakia. 6 Medicine for Older People, University Hospital Southampton NHS Foundation Trust, Southampton, UK. 7 Department of Rheumatology (...) of Health Sciences, University of Southampton, Southampton, UK. 2 Department Care I, Musculoskeletal System & Neurology, Dutch National Health Care Institute, Diemen, The Netherlands. 3 EULAR Standing Committee of People with Arthritis/Rheumatism in Europe (PARE), Zurich, Switzerland. 4 EULAR Young PARE, Zurich, Switzerland. 5 Slovak League Against Rheumatism, Piestany, Slovakia. 6 Medicine for Older People, University Hospital Southampton NHS Foundation Trust, Southampton, UK. 7 Department

Actions Cite Share Permalink Copy Page navigation Randomized Controlled Trial Complement Ther Clin Pract Actions . 2020 May;39:101166. doi: 10.1016/j.ctcp.2020.101166. Epub 2020 Apr 1. Respiratory Rehabilitation in Elderly Patients With COVID-19: A Randomized Controlled Study , , , , , Affiliations Expand Affiliations 1 Department of Geriatric Center, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, 570311, PR China. 2 Department of General Surgery, Hainan (...) Rehabilitation in Elderly Patients With COVID-19: A Randomized Controlled Study Kai Liu et al. Complement Ther Clin Pract . 2020 May . Free PMC article Show details Complement Ther Clin Pract Actions . 2020 May;39:101166. doi: 10.1016/j.ctcp.2020.101166. Epub 2020 Apr 1. Authors , , , , , Affiliations 1 Department of Geriatric Center, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, 570311, PR China. 2 Department of General Surgery, Hainan General Hospital (Hainan

Strategies For Risk Reduction and Management of Older Adults With Cardiovascular Disease During the COVID-19 Pandemic Strategies For Risk Reduction and Management of Older Adults With Cardiovascular Disease During the COVID-19 Pandemic - American College of Cardiology ') Search All Types Search or Menu . This article was authored by Nicole M. Orr, MD, FACC , and the Geriatric Cardiology Council. Share via: Clinical Topics: Keywords: Aged, SARS Virus, Angiotensin Receptor Antagonists (...) , Hydroxychloroquine, Mineralocorticoid Receptor Antagonists, Caregivers, Angiotensin-Converting Enzyme Inhibitors, COVID-19, Coronavirus, Coronavirus Infections, Neprilysin, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Neprilysin, Chloroquine, Subacute Care, Social Isolation, Skilled Nursing Facilities, Cardiovascular Diseases > > Strategies For Risk Reduction and Management of Older Adults With Cardiovascular Disease During the COVID-19 Pandemic Heart House 2400 N Street NW Washington, DC 20037 Phone: , ext

and outcomes for people aged over 60 years? 13 Grey Literature 24 Gaps in the evidence 25 Discussion 26 Applicability 28 References 31 Appendix A 35 Appendix B 36 Appendix C 45 Appendix D 46 COMMUNITY-BASED HEALTH PROMOTION FOR OLDER ADULTS APRIL 2019 | SAX INSTITUTE 5 Executive summary Background Older adults who are physically active maintain better health and cognitive function than adults who are not. Evidence-based strategies to increase health and wellbeing among older people are needed (...) Question 1: What community-based programs, that combine physical activity, with other activities addressing key health risk factors, have shown to be effective in improving the health behaviours and outcomes for people aged over 60 years? The evidence check identified 26 papers reporting on 23 different community-based programs for older adults (60+ years) that met the criteria for inclusion in this rapid review. Programs were developed in the United States, Canada, Brazil, several European countries

from a bank or post office. Consider action to ensure that older people are not concerned about being able to pay their telephone/broadband bills. Telephone communication providers should consider whether they are able to cap call and internet charges and provide unlimited use for elderly people during this period. What the evidence says We based these suggestions on the following research findings On quality of life older people report value in: ? Being able to manage on their own retaining (...) to meet basic needs o Having material resources to feel comfortable and independent 2 This review looked at qualitative research, in people aged 65 or over who were still living independently, that investigated their views about occupations that enhanced their wellbeing. Authors found that: Solitary occupations are described as positive and highly important to older people’s wellbeing. ? Older people described the need for autonomy in deciding what to do and when to do it; occupations needed

Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National (...) : Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Stroke Actions . 2020 Jun;51(6):1758-1765. doi: 10.1161/STROKEAHA.119.028643. Epub 2020 May 14. Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups , , , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 From the Faculty of Medicine, Institute for Medical Informatics, Biometry and Epidemiology