Latest & greatest articles for elderly

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Top results for elderly

161. Comparison between multicomponent and simultaneous dual-task exercise interventions in long-term nursing home residents: the Ageing-ONDUAL-TASK randomized controlled study Full Text available with Trip Pro

Comparison between multicomponent and simultaneous dual-task exercise interventions in long-term nursing home residents: the Ageing-ONDUAL-TASK randomized controlled study the potential benefits of dual-task interventions on older adults living in long-term nursing homes (LTNHs) from a multidimensional perspective are unknown. We sought to determine whether the addition of simultaneous cognitive training to a multicomponent exercise program offers further benefits to dual-task, physical (...) the multicomponent group significantly improved quality of life, and reduced anxiety and Fried frailty score (P < 0.05). No group-by-time interactions were found except for the chair-stand test in favour of the multicomponent group (P < 0.05).the addition of simultaneous cognitive training does not seem to offer significantly greater benefits to the evaluated multicomponent exercise program in older adults living in LTNHs.© The Author(s) 2019. Published by Oxford University Press on behalf of the British

2019 EvidenceUpdates

162. Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres. Full Text available with Trip Pro

) signified a 3.2 higher mortality hazard (95% confidence interval 3.1 to 3.2) over three years. Mortality varied noticeably with age, with a hazard ratio of 10.6 (8.5 to 13.3) in 18-29 year olds and 1.5 (1.4 to 1.6) in those older than 90. A positive troponin result was associated with an approximately 15 percentage points higher absolute three year mortality across all age groups. The excess mortality with a positive troponin result was heavily concentrated in the first few weeks. Results were analysed (...) Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres. To determine the relation between age and troponin level and its prognostic implication.Retrospective cohort study.Five cardiovascular centres in the UK National Institute for Health Research Health Informatics Collaborative (UK-NIHR HIC).257 948 consecutive patients undergoing troponin testing for any clinical reason between 2010 and 2017.All cause mortality.257 948

2019 BMJ

163. Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial. Full Text available with Trip Pro

Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial. To investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.Pragmatic, three armed, parallel group, individually randomised controlled trial.59 general (...) practices in the Netherlands.322 adults aged 50 and older with a chronic vestibular syndrome.Stand alone VR comprising a six week, internet based intervention with weekly online sessions and daily exercises (10-20 minutes a day). In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.The primary

2019 BMJ

164. Immunisations: babies up to 13 months of age

Immunisations: babies up to 13 months of age Immunisations: babies up to 13 months of age - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Register by 26 November to vote in the General Election on 12 December (...) . Promotional material Immunisations: babies up to 13 months of age This booklet covers all immunisations for babies during their first year of life. Published 29 July 2013 Last updated 4 November 2019 — From: Documents Ref: Public Health England gateway number 2019179 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use

2019 Public Health England

165. 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed-tomography (PET CT) as part of radical radiotherapy treatment planning for oesophageal cancer (all ages)

18F-fluorodeoxyglucose (FDG) positron emission tomography-computed-tomography (PET CT) as part of radical radiotherapy treatment planning for oesophageal cancer (all ages) NHS England » 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed-tomography (PET CT) as part of radical radiotherapy treatment planning for oesophageal cancer (all ages) Search Search Menu 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed-tomography (PET CT) as part of radical radiotherapy (...) treatment planning for oesophageal cancer (all ages) Document first published: 12 April 2019 Page updated: 12 April 2019 Topic: Publication type: , NHS England will not routinely commission 18F-FDG-PET CT as part of radical radiotherapy treatment planning for oesophageal cancer in accordance with the criteria outlined in this document. In creating this policy NHS England has reviewed this clinical condition and the options for its treatment. It has considered the place of this treatment in current

2019 NHS England

166. Pazopanib for inoperable and metastatic malignant granular cell tumour (all ages)

Pazopanib for inoperable and metastatic malignant granular cell tumour (all ages) NHS England » Pazopanib for inoperable and metastatic malignant granular cell tumour (all ages) Search Search Menu Pazopanib for inoperable and metastatic malignant granular cell tumour (all ages) Document first published: 12 April 2019 Page updated: 12 April 2019 Topic: Publication type: , This policy statement is to confirm that pazopanib is not recommended as a treatment option for inoperable and metastatic (...) malignant granular cell tumours (all ages). Document PDF 62 KB 3 pages Document PDF 58 KB 3 pages Document PDF 51 KB 4 pages Document PDF 87 KB 2 pages

2019 NHS England

167. Emicizumab as prophylaxis in people with severe congenital haemophilia A without factor VIII inhibitors (all ages)

Emicizumab as prophylaxis in people with severe congenital haemophilia A without factor VIII inhibitors (all ages) NHS England » Emicizumab as prophylaxis in people with severe congenital haemophilia A without factor VIII inhibitors (all ages) Search Search Menu Emicizumab as prophylaxis in people with severe congenital haemophilia A without factor VIII inhibitors (all ages) Document first published: 21 August 2019 Page updated: 21 August 2019 Topic: Publication type: , NHS England (...) will commission emicizumab as prophylaxis in people with severe congenital haemophilia A without factor VIII inhibitors in accordance with the criteria outlined in this policy. Document PDF 308 KB 22 pages Document PDF 446 KB 35 pages Document PDF 103 KB 4 pages Document PDF 103 KB 5 pages Document PDF 129 KB 2 pages

2019 NHS England

168. Brolucizumab–dbll (Beovu) - wet age-related macular degeneration

Brolucizumab–dbll (Beovu) - wet age-related macular degeneration CENTER FOR DRUG EVALUATION AND RESEARCH APPLICATION NUMBER: 761125Orig1s000 CLINICAL PHARMACOLOGY REVIEW(S) 1 Office of Clinical Pharmacology Review BLA Number 761125 Link to EDR Link Submission Date 02/07/2019 Submission Type Priority Proposed Brand Name Beovu Generic Name Brolucizumab (RTH258) Dosage Form and Strength 120 mg/mL solution for intravitreal injection Route of Administration Local Proposed Indication Treatment (...) of neovascular age-related macular degeneration (AMD) Applicant Novartis Pharmaceuticals Corporation Associated IND IND 112023 OCP Review Team Abhay Joshi, Ph.D. Philip Colangelo, Pharm.D., Ph.D. OCP Final Signatory John A. Lazor, Pharm.D. Office of Clinical Pharmacology Division IV Director Reference ID: 44719932 Table of Contents Table of Contents 2 1. EXECUTIVE SUMMARY 3 1.1 Recommendations 3 1.2 Post-Marketing Requirements and Commitments 4 2. SUMMARY OF CLINICAL PHARMACOLOGY ASSESSMENT 4 2.1

2019 FDA - Drug Approval Package

169. Effect of Clinical Geriatric Assessments and Collaborative Medication Reviews by Geriatrician and Family Physician for Improving Health-Related Quality of Life in Home-Dwelling Older Patients Receiving Polypharmacy: A Cluster Randomized Clinical Trial (Abstract)

Effect of Clinical Geriatric Assessments and Collaborative Medication Reviews by Geriatrician and Family Physician for Improving Health-Related Quality of Life in Home-Dwelling Older Patients Receiving Polypharmacy: A Cluster Randomized Clinical Trial Polypharmacy and inappropriate drug regimens are major health concerns among older adults. Various interventions focused on medication optimization strategies have been carried out, but the effect on patient-relevant outcomes remains uncertain.To (...) investigate the effect of clinical geriatric assessments and collaborative medication reviews by geriatrician and family physician (FP) on health-related quality of life and other patient-relevant outcomes in home-dwelling older patients receiving polypharmacy.Cluster randomized, single-blind, clinical trial. Norwegian FPs were recruited from March 17, 2015, to March 16, 2017, to participate in the trial with their eligible patients. Participants were home-dwelling patients 70 years or older, using

2019 EvidenceUpdates

170. Increasing Influenza and Pneumococcal Vaccination Uptake in Seniors Using Point-of-Care Informational Interventions in Primary Care in Singapore: A Pragmatic, Cluster-Randomized Crossover Trial Full Text available with Trip Pro

Increasing Influenza and Pneumococcal Vaccination Uptake in Seniors Using Point-of-Care Informational Interventions in Primary Care in Singapore: A Pragmatic, Cluster-Randomized Crossover Trial Objectives. To evaluate the effectiveness of point-of-care informational interventions in general practitioner clinics to improve influenza and pneumococcal vaccination uptake among elderly patients.Methods. We conducted a pragmatic, cluster-randomized crossover trial in 22 private general practitioner (...) clinics in Singapore, from November 2017 to July 2018. We included all patients aged 65 years or older. Clinics were assigned to a 3-month intervention (flyers and posters encouraging vaccination) plus 1-month washout period, and a 4-month control period (usual care). Primary outcomes were differences in vaccination uptake rates between periods. Secondary outcomes were identification of other factors associated with vaccination uptake.Results. A total of 4378 and 4459 patients were included

2019 EvidenceUpdates

171. Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and Function in Older Adults: A Randomized Clinical Trial (Abstract)

Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and Function in Older Adults: A Randomized Clinical Trial Postoperative delirium (POD) is a common condition for older adults, contributing to their functional decline.To investigate the effectiveness of the Tailored, Family-Involved Hospital Elder Life Program (t-HELP) for preventing POD and functional decline in older patients after a noncardiac surgical procedure.A 2-arm, parallel-group, single (...) . Secondary outcomes included the pattern of functional and cognitive changes (activities of daily living [ADLs], instrumental activities of daily living [IADLs], Short Portable Mental Status Questionnaire [SPMSQ]) from hospital admission to 30 days after discharge, and the length of hospital stay (LOS).Of the 475 patients screened for eligibility, 281 (171 [60.9%] male, mean [SD] age 74.7 [5.2] years) were enrolled and randomized to receive t-HELP (n = 152) or usual care (n = 129). Postoperative delirium

2019 EvidenceUpdates

172. The effect of volunteers' care and support on the health outcomes of older adults in acute care: A systematic scoping review Full Text available with Trip Pro

terms: 'hospital', 'volunteer', 'sitter', 'acute care', 'older adults', 'confusion', 'dementia' and 'frail'. The search was limited to papers written in English and published from 2002-2017. Inclusion criteria were studies involving the use of hospital volunteers in the care or support of older adult patients aged ≥ 65 years, or ≥ 50 years for Indigenous peoples, with chronic health conditions, cognitive impairment and/or physical decline or frailty, within the acute inpatient settings.Of the 199 (...) The effect of volunteers' care and support on the health outcomes of older adults in acute care: A systematic scoping review To examine the available evidence on the effects of care and support provided by volunteers on the health outcomes of older adults in acute care services.Acute hospital inpatient populations are becoming older, and this presents the potential for poorer health outcomes. Factors such as chronic health conditions, polypharmacy and cognitive and functional decline

2019 EvidenceUpdates

173. The community mental health framework for adults and older adults

The community mental health framework for adults and older adults NHS England » The community mental health framework for adults and older adults Search Search Menu The community mental health framework for adults and older adults Document first published: 29 September 2019 Page updated: 27 September 2019 Topic: , Publication type: The Community Mental Health Framework describes how the Long Term Plan’s vision for a place-based community mental health model can be realised, and how community

2019 NHS England

174. Effectiveness of a Question Prompt List Intervention for Older Patients Considering Major Surgery: A Multisite Randomized Clinical Trial (Abstract)

Effectiveness of a Question Prompt List Intervention for Older Patients Considering Major Surgery: A Multisite Randomized Clinical Trial Poor preoperative communication can have serious consequences, including unwanted treatment and postoperative conflict.To compare the effectiveness of a question prompt list (QPL) intervention vs usual care on patient engagement and well-being among older patients considering major surgery.This randomized clinical trial used a stepped-wedge design to randomly (...) assign patients to a QPL intervention (n = 223) or usual care (n = 223) based on the timing of their visit with 1 of 40 surgeons at 5 US study sites. Patients were 60 years or older with at least 1 comorbidity and an oncologic or vascular (cardiac, neurosurgical, or peripheral vascular) problem that could be treated with major surgery. Family members were also enrolled (n = 263). The study dates were June 2016 to November 2018. Data analysis was by intent-to-treat.A brochure of 11 questions to ask

2019 EvidenceUpdates

175. Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism. Full Text available with Trip Pro

Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism. It is unclear whether levothyroxine treatment provides clinically important benefits in adults aged 80 years and older with subclinical hypothyroidism.To determine the association of levothyroxine treatment for subclinical hypothyroidism with thyroid-related quality of life in adults aged 80 years and older.Prospectively planned combined analysis of data (...) involving community-dwelling adults aged 80 years and older with subclinical hypothyroidism. Data from a randomized clinical trial were combined with a subgroup of participants aged 80 years and older from a second clinical trial. The trials were conducted between April 2013 and May 2018. Final follow-up was May 4, 2018.Participants were randomly assigned to receive levothyroxine (n = 112; 52 participants from the first trial and 60 from the second trial) or placebo (n = 139; 53 participants from

2019 JAMA

176. Meal Delivery Programs for Community Seniors: A Review of Clinical Effectiveness

Meal Delivery Programs for Community Seniors: A Review of Clinical Effectiveness Meal Delivery Programs for Community Seniors: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Meal Delivery Programs for Community Seniors: A Review of Clinical Effectiveness Meal Delivery Programs for Community Seniors: A Review of Clinical Effectiveness Last updated: January 22, 2019 Project Number: RC1060-000 Product Line: Research Type: Devices and Systems Report Type: Summary (...) with Critical Appraisal Result type: Report Question What is the clinical effectiveness of meal delivery nutrition programs for older adults living in the community? Key Message One randomized controlled trial (RCT) and two non-randomized studies were identified regarding the clinical effectiveness of meal delivery nutrition programs for community-dwelling older adults. Low quality evidence from one RCT and one single-arm non-randomized study showed that meal delivery nutrition programs may improve

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

177. Mobilization for Hospitalized Older Adults: Guidelines

Mobilization for Hospitalized Older Adults: Guidelines Mobilization for Hospitalized Older Adults: Guidelines | CADTH.ca Find the information you need Mobilization for Hospitalized Older Adults: Guidelines Mobilization for Hospitalized Older Adults: Guidelines Last updated: February 19, 2019 Project Number: RA1011-000 - RC1080-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What are the evidence-based guidelines regarding (...) mobilization to prevent or reduce functional decline in hospitalized older adults? Key Message No relevant evidence-based guidelines were identified regarding mobilization to prevent or reduce functional decline in hospitalized older adults. Files Rapid Response Reference List Published : February 19, 2019 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter:

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

178. Avoidance of Physical Restraint Use among Hospitalized Older Adults: A Review of Clinical Effectiveness and Guidelines

Avoidance of Physical Restraint Use among Hospitalized Older Adults: A Review of Clinical Effectiveness and Guidelines Avoidance of Physical Restraint Use among Hospitalized Older Adults: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Avoidance of Physical Restraint Use among Hospitalized Older Adults: A Review of Clinical Effectiveness and Guidelines Avoidance of Physical Restraint Use among Hospitalized Older Adults: A Review of Clinical (...) Effectiveness and Guidelines Last updated: February 28, 2019 Project Number: RC1079-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness regarding the use of physical restraints among hospitalized older adults? What is the clinical effectiveness regarding the avoidance of physical restraints among hospitalized older adults? What are the evidence-based guidelines regarding the use or avoidance

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

179. Senior Friendly Hospital Care: A Review of Guidelines

Senior Friendly Hospital Care: A Review of Guidelines Senior Friendly Hospital Care: A Review of Guidelines | CADTH.ca Find the information you need Senior Friendly Hospital Care: A Review of Guidelines Senior Friendly Hospital Care: A Review of Guidelines Last updated: February 28, 2019 Project Number: RC1078-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What are the evidence-based guidelines regarding senior (...) friendly hospital care? Key Message Two guidelines on senior friendly hospital care were identified. A guideline from Ontario was developed to help hospitals perform as senior friendly organizations based on the five components of the Senior Friendly Hospital Framework, and to ensure that the recommendations were implemented. The identified Irish guideline provided detailed recommendations with respect to dementia-related design issues and the Universal Design of dementia-friendly hospitals for new

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

180. Cannabidiol (Epidyolex) - to treat patients from the age of two years who have Lennox-Gastaut syndrome or Dravet syndrome

Cannabidiol (Epidyolex) - to treat patients from the age of two years who have Lennox-Gastaut syndrome or Dravet syndrome Official address Domenico Scarlattilaan 6 ? 1083 HS Amsterdam ? The Netherlands An agency of the European Union Address for visits and deliveries Refer to www.ema.europa.eu/how-to-find-us Send us a question Go to www.ema.europa.eu/contact Telephone +31 (0)88 781 6000 © European Medicines Agency, 2019. Reproduction is authorised provided the source is acknowledged. EMA/428834 (...) /2019 EMEA/H/C/004675 Epidyolex (cannabidiol) An overview of Epidyolex and why it is authorised in the EU What is Epidyolex and what is it used for? Epidyolex is a medicine used in addition to clobazam, another epilepsy medicine, to treat patients from the age of two years who have Lennox-Gastaut syndrome or Dravet syndrome, rare types of epilepsy that begin in childhood and can continue into adulthood. Symptoms include multiple types of seizure (fits), abnormal electrical activity in the brain

2019 European Medicines Agency - EPARs