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through agreed national centres in the UK for all paediatric age groups (London, Liverpool and Birmingham). Psoriatic arthritis – adalimumab is licensed for psoriatic arthritis in adults but not in children. It has also been used in other rheumatological conditions which may require formal financial approval. Contraindications: • Moderate or severe heart failure. • Severe infection (including but not limited to active TB and other opportunistic infections). • Hypersensitivity to the active substance (...) by the child. The manufacturers consider it safe to use adalimumab while breastfeeding. Screening and recommendations before starting: Clearly documented decision to start adalimumab treatment with the indication noted. Documented adherence to concomitant medication plan (e.g. DMARDs, steroids, other immunosuppression, prophylactic antibiotics/antivirals etc.). Paediatric and adolescent rheumatology nurse specialist has delivered appropriate education regarding the medication with documentation
be revisited once the child matures. These issues must be discussed prior to starting methotrexate treatment. Health professionals should be aware that methotrexate can cause embryotoxicity and teratogenicity, and they should avoid handling of it if they are concerned. Vaccinations: The Department of Health publication ‘Immunisation against Infectious disease’ (the Green Book) is regularly updated and should be considered as the definitive source of information about vaccination. • Live vaccines – children (...) • Improving compliance with oral methotrexate guidelines. National Patient Safety Alert (NPSA). June 2006 updated June 2018. https://www.sps.nhs.uk/articles/npsa-alert- improving-compliance-with-oral-methotrexate-guidelines-2006/ • NHS Improvements Never Event List 2018 https://improvement.nhs.uk/documents/2899/Never_Events_list_2018_FINAL_v6.pdf • Paediatric Formulary Committee. BNF for Children (online) London: BMJ Group, Pharmaceutical Press, and RCPCH Publications http://www.medicinescomplete.com
provide them with the discounts agreed in the patient access schemes for these technologies. NB 2. At the time of production of this document the manufacturer has not sought a paediatric and adolescent licence for the S/C pen device and so only the prefilled syringe is licenced for use in children. Use – licenced/not licenced/NHSE pathway: Licensed for indications listed above and present on NHS England pathway within document: Biologic Therapies for the use in Juvenile Idiopathic Arthritis (2015 (...) medication who are exposed to varicella and do not have immunity require prophylactic aciclovir and selected patients may require passive immunisation using VZIG. See Public Health England Guidelines for details. Patients developing chickenpox or shingles should be treated with aciclovir and have their immunosuppressive medication withheld until they have recovered. Authors: Dr Peter Bale, Consultant Paediatric Rheumatologist (Addenbrookes Hospital) Clare Nash, BSPAR pharmacy lead (Sheffield Children’s
The role of dietary fibre and prebiotics in the paediatric diet Dietary fibres are resistant to digestion and absorption. Prebiotics are fermentable dietary fibres that confer health benefits through their effects on microbiome composition and activity. The range of physiological benefits from consuming dietary fibres is broad. Encouraging children to eat fibre-rich foods promotes a nutrient-dense diet. Introducing a variety of dietary fibre sources to young children helps establish future (...) dietary choices and a more diverse intestinal microbiota. Low fibre intake is associated with a higher prevalence of constipation and obesity. Keywords : Children; Dietary fibre; Microbiome; Prebiotics
of Technology, Brisbane, Australia. 7 Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia. 8 University Children's Hospital, Vienna, Austria. 9 Breathing Institute, Children's Hospital Colorado, Dept of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA. 10 National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA. 11 Pediatric Dept, Hôpital Erasme, Université Libre de Bruxelles (U.L.B.), Brussels, Belgium. 12 Dept (...) of Paediatrics, Antwerp University Hospital, Antwerp, Belgium. 13 Child Health, University of Aberdeen, Aberdeen, UK firstname.lastname@example.org. PMID: 32165403 DOI: Item in Clipboard Does Treatment Guided by Exhaled Nitric Oxide Fraction Improve Outcomes in Subgroups of Children With Asthma? Shona S Fielding et al. Eur Respir J . 2020 . Show details Eur Respir J Actions . 2020 May 21;55(5):1901879. doi: 10.1183/13993003.01879-2019. Print 2020 May. Authors , , , , , , , , , , , , , Affiliations 1 Medical
Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Diabetes Care Actions . 2020 Jul;43(7):1553-1556. doi: 10.2337/dc19-1944. Epub 2020 Apr 28. Screening and Treatment Outcomes in Adults and Children With Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Division of Endocrinology, Department of Pediatrics, The Hospital (...) for Sick Children, University of Toronto, Toronto, Ontario, Canada email@example.com. 2 Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. 3 Division of Endocrinology and Metabolism, St. Joseph's Health Care, London Health Sciences Centre, Western University, London, Ontario, Canada. 4 Division of Gastroenterology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. 5 Department
and maternal health data and intelligence. Published 14 June 2017 Last updated 12 March 2019 — From: Contents Public Health England (PHE) collects and analyses available child and maternal health data and produces intelligence resources to help with improving services and outcomes. This guidance supports commissioners, service planners and other healthcare professionals with using these resources to make or influence decisions about services that improve the health of children, young people and pregnant (...) women. Child and maternal health statistics PHE publishes several collections of . You can use these to help improve decision making when planning services for mothers, children and young people. Overview of child health and child health profiles The on the Fingertips data website provide a snapshot of child health in upper-tier local authority areas. These are part of an overview of child health that brings together indicators for local government and CCG areas across several different themes
of Pediatrics recommends that all adolescents be screened for alcohol and drug use and that, based on the results, clinicians conduct further assessment, provide guidance and brief counseling interventions, and, if appropriate, refer for treatment . The American Academy of Family Physicians' recommendation on interventions to address drug use in children and adolescents is currently under review. Members of the U.S. Preventive Services Task Force at the time this recommendation was finalized are Virginia (...) Illicit Drug Use in Children, Adolescents, and Young Adults: Primary Care-Based Interventions Recommendation | United States Preventive Services Taskforce Toggle navigation Main navigation Main navigation Recommendation to see the latest documents available. Recommendation Summary Population Recommendation Children and Adolescents without a Substance Use Disorder The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of primary care-based
Paediatric multisystem inflammatory syndrome temporally associated with COVID-19 1 Dear Colleagues We are writing to you in regards to a clinical alert published by the Royal College of Paediatrics and child Health on the 1 st of May 2020 highlighting a new COVID-19-associated paediatric hyper-inflammatory presentation (Guidance - Paediatric multisystem inflammatory syndrome temporally associated with COVID-19). Although COVID-19 respiratory presentation in children has been rare, several (...) children have recently presented to hospitals in the South Thames region with the described Paediatric multisystem inflammatory syndrome temporally associated with COVID-19. Many of the children have been severely unwell at presentation requiring resuscitation and transfer to paediatric intensive care. As the anaesthetic team you may be asked to review and assist in their resuscitation and stabilisation. We thought it may be helpful to summarise some of the salient features of the presentation
Hypertension Canada’s 2020 comprehensive guidelines for the prevention, diagnosis, risk assessment, and treatment of hypertension in adults and children Guidelines Hypertension Canada’s 2020 Evidence Review and Guidelines for the Management of Resistant Hypertension SwapnilHiremath,MD,MPH, a RuthSapir-Pichhadze,MD,MSc,PhD, b MerandaNakhla,MD,MSc, c JonathanY.Gabor,MD,MSc, d NadiaA.Khan,MD,MSc, e LauraM.Kuyper,MD, e MarcelRuzicka,MD,PhD, a SheldonW.Tobe,MD,MScH, f KarenTran,MD, e DoreenM.Rabi,MD (...) 25, 2019. After the discussions, the guidelines were further revised and ?nalized for anelectronic vote by all 81 members of the HCGC, with > 70% support required for approval of each new guideline. Guidelines for the diagnosis, assessment, prevention, and treatment of hyper- tension in adults and children are published separately. 10 Key Messages Resistant hypertension (RHT) is de?ned as blood pressure (BP) above target despite 3 or more BP- lowering drugs at optimal doses preferably including
Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children Global Navigation Other sites: European Centre for Disease Prevention and Control An agency of the European Union Main Navigation Secondary Navigation Search Search Search Search Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children (...) Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children Risk assessment 15 May 2020 Cite: European Centre for Disease Prevention and Control. Paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children – 15 May 2020. ECDC: Stockholm; 2020. Several countries affected by the coronavirus disease (COVID-19) pandemic recently reported cases of children that were hospitalised in intensive care due to a rare paediatric inflammatory
, India. Lynne Mofenson, Elizabeth Glaser Pediatric AIDS Foundation, Washington DC, USA. Srinivas Murthy, BC Children’s Hospital, Vancouver, Canada. Pablo Rojo, Pediatric Infectious Diseases Unit, Hospital 12 de Octubre, Madrid, Spain. Calum Semple, Outbreak Medicine, University of Liverpool, UK. Louise Sigfrid, Centre for Tropical Medicine and Global Health, Oxford University, UK. Elizabeth Whittaker, Paediatric Infectious Diseases and Immunology, Imperial College, London, UK. Additional inputs Rosie (...) adults. Pediatr Pulmonol. 2020;55(5):1169-74. Epub 2020/03/07 Wei M, Yuan J, Liu Y, Fu T, Yu X, Zhang ZJ. Novel Coronavirus Infection in Hospitalized Infants Under 1 Year of Age in China. JAMA. 2020. Epub 2020/02/15 Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. N Engl J Med. 2020;382(17):1663-5. Epub 2020/03/19 Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, et al. Characteristics and Outcomes of Children With Coronavirus Disease 2019
will clearly differ, the International Society of Thrombosis and Haemostasis (ISTH) have defined the aims of prophylaxis in relation to joint health at onset : Primary prophylaxis Commences in early childhood at the latest before the second joint bleed or the age of 3 years, in the absence of documented joint disease, with the aim that the child reaches maturity with normal joints. , Secondary prophylaxis Commences after two or more joint bleeds, but before the onset of proven joint disease. It is likely (...) , compared to 38·2 (22·9–63·8) when treated OD. This supports the role of emicizumab for prophylaxis in PWSHA over the age of 12 years. The limited data in children with SHA and an inhibitor suggest that emicizumab will be efficacious in non‐inhibitor children. Caution is advised in this age group, who may be significantly more active than the older cohort and the paediatric group with inhibitors, any increase in bleed frequency will adversely impact on joint health and quality of life. There are even
susceptibility? The Lancet Child & Adolescent Health. 3. Shen K, Yang Y, Wang T, Zhao D, Jiang Y, Jin R, et al. Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts’ consensus statement. World Journal of Pediatrics. 2020. 4. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72?314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239-42 (...) (like Sciensano, CSS/HGR, AFMPS/FAGG and SPF/FOD). 19 May 2020 COVID-19 – KCE CONTRIBUTIONS COVID-19 TRANSMISSION AND CHILDREN VICKY JESPERS 1 ? TABLE OF CONTENTS 1 SUMMARY 2 1.1 OBJECTIVES 2 1.2 METHODS 2 1.3 KEY RESULTS 2 1.4 CONCLUSION 2 2 PROBLEM DESCRIPTION 2 3 OBJECTIVE 3 4 METHODS 3 5 RESULTS 3 5.1 EPIDEMIOLOGICAL FEATURES AND CONTACT TRACING STUDIES 3 5.1.1 Household transmission 3 5.1.2 Child onward transmission 4 5.1.3 Epidemiological data from Sweden - example 4 5.1.4 Epidemiological data
a number of seriously ill children presenting with signs of circulatory shock and hyperinflammatory state, with features consistent with toxic shock or KD (Table 1). Some of the tested children also were positive for SARS-CoV-2 infection. A case of classic KD with concurrent COVID-19 had already been reported on 7 April in the United States . On 1 May, the Royal College of Paediatrics and Child Health published guidance on the clinical management of children with a presentation of paediatric (...) children accounted for less than 1% of all reported cases in China in early analyses [36,37]. Recent data from the US showed that 5.7%–20% of paediatric cases were hospitalised, a majority of them infants . A recent study from Italy, involving 11 exclusively paediatric hospitals and 51 paediatric units across Italy, showed that hospital admission was inversely related to age (p?0.01; Fisher exact test) , as also described by the TESSy data . Data in TESSy show an elevated rate
that all pediatric Received April 7, 2020; accepted April 8, 2020. From the Division of Gastroenterology, Hepatology and Nutrition and the Research and Learning Institutes, Hospital for Sick Children, Depart- ment of Paediatrics and the Wilson Centre, University of Toronto, Toronto,Canada,the y SectionofPediatricGastroenterology,Hepatology and Nutrition, Baylor College of Medicine, Houston, TX, and the z Department of Pediatrics, Section of Gastroenterology, Hepatology, and Nutrition, Medical College (...) , McGill University, Montreal, QC, Canada; Jane Alookaran, MD, University of Texas Health Science Center, Houston, TX; Ayesha S. Baig, MD, University of Rochester, New York, NY; Tavleen Bhatia, MD, Geisinger Commonwealth School of Medicine, Scranton, PA; Samuel Bitton, MD, Cohen Children’s Medical Center of New York, New Hyde Park, NY; Herbert Brill, MD, MBA, Department of Pediatrics, McMaster Children’s Hospital, Hamilton,ON,Canada;NicholasJ.Carman,MBBS,Children’sHospital ofEasternOntario,Ottawa
and Dietetics, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK 5 Department of Paediatrics, University of Cambridge, Cambridge, UK 6 School of Medicine, University of Leeds, Leeds, UK 7 Department of Women’s and Children’s Health, Institute of Translational Medicine (Child Health), Alder Hey Children’s NHS Foundation Trust, University of Liverpool, Liverpool, UK 8 Neonatal Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon-Bron, France 9 Neonatal Unit, Chelsea and Westminster Hospital (...) Routine gastric residual volume measurement to guide enteral feeding in mechanically ventilated infants and children: the GASTRIC feasibility study Routine gastric residual volume measurement to guide enteral feeding in mechanically ventilated infants and children: the GASTRIC feasibility study Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page
Interventions to Prevent Illicit and Nonmedical Drug Use in Children, Adolescents, and Young Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. Illicit and nonmedical (use in ways other than instructed) drug use is common in adolescents and young adults and increases the risk of harmful outcomes such as injuries, violence, and poorer academic performance.To review the benefits and harms of interventions to prevent illicit and nonmedical drug use (...) in children, adolescents, and young adults to inform the US Preventive Services Task Force.MEDLINE, PubMED, PsycINFO, and the Cochrane Central Register of Controlled Trials (January 1, 2013, to January 31, 2019 [children and adolescents]; January 1, 1992, to January 31, 2019 [young adults <25 years]); surveillance through March 20, 2020.Clinical trials of behavioral counseling interventions to prevent initiation of illicit and nonmedical drug use among young people.Critical appraisal was completed
Primary Care-Based Interventions to Prevent Illicit Drug Use in Children, Adolescents, and Young Adults: US Preventive Services Task Force Recommendation Statement. In 2017, an estimated 7.9% of persons aged 12 to 17 years reported illicit drug use in the past month, and an estimated 50% of adolescents in the US had used an illicit drug by the time they graduated from high school. Young adults aged 18 to 25 years have a higher rate of current illicit drug use, with an estimated 23.2% currently (...) using illicit drugs. Illicit drug use is associated with many negative health, social, and economic consequences and is a significant contributor to 3 of the leading causes of death among young persons (aged 10-24 years): unintentional injuries including motor vehicle crashes, suicide, and homicide.To update its 2014 recommendation, the USPSTF commissioned a review of the evidence on the potential benefits and harms of interventions to prevent illicit drug use in children, adolescents, and young
Interventions for increasing fruit and vegetable consumption in children aged five years and under. Insufficient consumption of fruits and vegetables in childhood increases the risk of future non-communicable diseases, including cardiovascular disease. Testing the effects of interventions to increase consumption of fruit and vegetables, including those focused on specific child-feeding strategies or broader multicomponent interventions targeting the home or childcare environment is required (...) . parent nutrition education and preschool policy changes) in increasing child fruit and vegetable intake. Two trials examined the effect of a nutrition education intervention delivered to children in increasing child fruit and vegetable intake. One trial examined the impact of a child-focused mindfulness intervention in increasing vegetable intake. We judged 23 of the 80 included trials as free from high risks of bias across all domains. Performance, detection and attrition bias were the most common