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(SCD) is characterized by chronic pain and episodic acute pain caused by vasoocclusive crises, often requiring high doses of opioids for prolonged periods. In humanized mouse models of SCD, a synthetic cannabinoid has been found to attenuate both chronic and acute hyperalgesia. The effect of cannabis on chronic pain in adults with SCD is unknown. Objective: To determine whether inhaled cannabis is more effective than inhaled placebo in relieving chronic pain in adults with SCD. Design, setting (...) . Roy NB, Fortin PM, Bull KR, Doree C, Trivella M, Hopewell S, Estcourt LJ. Roy NB, et al. Cochrane Database Syst Rev. 2017 Jul 3;7(7):CD012380. doi: 10.1002/14651858.CD012380.pub2. Cochrane Database Syst Rev. 2017. PMID: 28672087 Free PMC article. Review. Show more similar articles References National Conference of State Legislatures State medical marijuana laws. Accessed May 31, 2019. Kosiba JD, Maisto SA, Ditre JW. Patient-reported use of medical cannabis for pain, anxiety, and depression
with maternal marijuana use in the first trimester, but not for the second or third trimester was observed. As no new evidence was found in the updated search, there continues to be insufficient evidence to demonstrate an association between cannabis smoking and the incidence of cancer in offspring. Conclusion: There is insufficient evidence to demonstrate an association between parental cannabis use and subsequent risk of developing any malignancies in offspring. 7.Are cannabis or cannabinoids an effective (...) Cancer and the Health Effects of Cannabis and Cannabinoids: An update of the systematic review by the National Academies of Sciences, Engineering, and Medicine (2017) Consensus Study Report Evidence Summary 23-2 A Quality Initiative of the Program in Evidence-Based Care (PEBC), Ontario Health (Cancer Care Ontario) Cancer and the Health Effects of Cannabis and Cannabinoids: An update of the systematic review by the National Academies of Sciences, Engineering, and Medicine (2017) Consensus Study
among critically ill patients admitted to an intensive care unit with an infection (Gacouin et al., 2020). The effects of cannabis use and cannabinoids, such as tetrahydrocannabinol (THC) and cannabidiol (CBD), on immune functioning are complex and not yet well understood. However, a growing body of preclinical studies and several studies involving humans suggest that THC and CBD can affect the immune system, including suppressing its ability to mount a response to fight off infections (Cabral (...) COVID 19, Alcohol and Cannabis Use www.ccsa.ca • www.ccdus.ca Canadian Centre on Substance Use and Addiction • Centre canadien sur les dépendances et l’usage de substances Page 1 COVID-19, Alcohol and Cannabis Use This backgrounder to the infographic, COVID-19, Alcohol and Cannabis Use, describes some of the evidence-based associations between COVID-19, alcohol and cannabis use. It is intended for a broad audience, including health professionals, policy makers and researchers
Counselling adolescents and parents about cannabis: A primer for health professionals While cannabis use among adolescents is frequent in Canada, youth do recognize the potential harms, and increasingly expect knowledgeable health care providers to discuss substance use in everyday practice. This practice point provides sound, evidence-based tools to help health professionals address non-medical (recreational) cannabis use and its related risks. After highlighting how to make the clinical (...) setting a safe space for youth to talk about psychoactive substances, specific strategies for approaching cannabis use in effective, developmentally appropriate ways are described. Consistent with current literature, screening questionnaires to help structure discussion and identify adolescents who may benefit from more specialized interventions are recommended. Because one in six adolescents who experiments with cannabis goes on to misuse it, appraising their willingness to change risky behaviours
on the lung and immune defenses. In ElSohly (ed.), Marijuana and the Cannabinoids, pp. 253–275. Totowa, New Jersey: Humana Press. Taylor, D. R., Poulton, R., Moffit, T. E., Ramankutty, P., & Sears, M. R. (2000). The respiratory effects of cannabis dependence in young adults. Addiction, 95(11), 1669–1677. Tetrault, J. M., Crothers, K., Moore, B. A., Mehra, R., Concato, J., & Fiellin, D. A. (2007). Effects of marijuana smoking on pulmonary function and respiratory complications: A systematic review (...) Group: https://www.cannabisrehab.org/ Cannabis Resources • Canadian Institute for Substance Use Research, Safer Cannabis Use: https://www.heretohelp.bc.ca/infosheet/safer-cannabis-use-marijuana-hash-hash-oil • Centre for Addiction and Mental Health, Canada’s Lower-Risk Cannabis Use Guidelines: https://www.camh.ca/-/media/files/pdfs---reports-and-books---research/canadas-lower-risk- guidelines-cannabis-pdf.pdf • Government of Canada, Cannabis in Canada: Get the facts: https://www.canada.ca/en
f , x W. Burke Affiliations Stony Brook Medicine, Stony Brook, NY, USA c DOI: | Publication History Published online: January 13, 2020 Accepted: December 11, 2019 ; Received: October 24, 2019 ; To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Highlights • Tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) affect the human endocannabinoid system. • Cannabinoids reduce chemotherapy induced nausea or vomiting (CINV (...) ) and neuropathic pain. • Each state has its own regulations for medical and recreational cannabis use. • Effects of cannabinoids on chemotherapy, immunotherapy, and tumor growth remain under investigation. • Providers should focus indications, alternatives, risks and benefits of medical cannabis use to make appropriate referrals. Keywords: , , , , , To access this article, please choose from the options below Log In Register Purchase access to this article Claim Access If you are a current subscriber
Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia Syndrome (POTS) and Related Disorders of Chronic Orthostatic Intolerance Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia Syndrome (POTS) and Related Disorders of Chronic Orthostatic Intolerance - Canadian Journal of Cardiology Go search , P357-372, March 01, 2020 Powered By Mendeley Share on Canadian Cardiovascular Society Position Statement on Postural Orthostatic (...) Tachycardia Syndrome (POTS) and Related Disorders of Chronic Orthostatic Intolerance Satish R. Raj Correspondence Corresponding author: Dr Satish R. Raj, GAC70 HRIC Building, University of Calgary, 3280 Hospital Dr NW, Calgary, Alberta T2N 4Z6, Canada. Tel.: +1-403-210-6152; fax: +1-403-210-9444. Affiliations Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada Juan C. Guzman Affiliations Department of Medicine, McMaster University
of Canada. Health Canada. Information for Health Care Professionals: Cannabis (marihuana, marijuana) and the Cannabinoids. Ottawa, ON: Health Canada; 2018. Retrieved from https://www.canada.ca/content/dam/ hc-sc/documents/services/drugs-medication/cannabis/ information-medical-practitioners/information-health- care-professionals-cannabis-cannabinoids-eng.pdf 13. Hackam DG. Cannabis and stroke: systematic appraisal of case reports. Stroke. 2015;46(3):852–56. 14. Hemachandra D, McKetin R, Cherbuin N, et (...) withdrawal symptoms in older adults, as well as the presentation of can- nabis hyperemesis syndrome. (9) Cannabis is a plant that contains hundreds of com- pounds, including cannabinoids which act on the endogenous cannabinoid (endocannabinoid) system. Certain cannabi- noids act by influencing reward, motivation, and substance- related cues. Notably, delta-9-tetrahydro-cannabinol (THC) and cannabidiol (CBD) are two cannabinoids that have been studied the most. They exert various effects by binding
) was enacted, establishing a framework for the possession, distribution, sale and production of cannabis in Canada. (5) Cannabis is defined in the Act to include marijuana, hashish, hash oil or any other preparation of the cannabis plant. (5) In 2016, 16.9% of Canadian women between the ages of 15-44 reported past year use of cannabis which was an increase from the self reported 12.6% in 2015. (6) In British Columbia (BC), approximately 3.5% of pregnant women and individuals reported cannabis use (...) -on-Obstetric-Practice/Marijuana- Use-During-Pregnancy-and-Lactation?IsMobileSet=false n Midwives Association of British Columbia. Is it safe to use weed during pregnancy? https://www.bcmidwives.com/cgi/page.cgi/_zine.html/News_Announcements/Is_it_ safe_to_use_weed_during_pregnancy_ n Canadian Association of Midwives. Cannabis Use during Pregnancy. https:// canadianmidwives.org/2018/10/15/cannabis-use-during-pregnancy/ n Champlain Maternal Newborn Regional Program (CMNRP). Cannabis and Lactation Discussion
Position Statement on the medicinal use of Cannabinoids in Pain Medicine Faculty Position Statement on the medicinal use of Cannabinoids in Pain Medicine Update following the publication of NICE Guidance NG144 (11 November 2019) This statement is focused on the issues relating to cannabis derived medicinal products in relation to Pain Medicine. It does not comment on other areas of medical practice or recreational use, which lie outside our remit. The issue of cannabis, its extracts (...) , Radbruch L, Petzke F, Häuser W. Cannabis-based medicines for chronic neuropathic pain in adults. Cochrane Database of Systematic Reviews 2018, Issue 3. Art. No.: CD012182. DOI: 10.1002 /14651858.CD012182.pub2 3. Stockings E, Campbell G, Hall WD, Nielsen S, Zagic D, Rahman R, et al. Cannabis and cannabinoids for the treatment of people with chronic non-cancer pain conditions: a systematic review and meta-analysis of controlled and observational studies. PAIN. 2018;159(10):1932-54. 4. National Academies
recommendation) — Nabilone is off-label for pain and has limited evidence of benefit. However, it is less expensive than nabiximols and dosing is more consistent than for smoked cannabis — Nabiximols is expensive and, in some provinces, only available through specialist prescribing or special authorization. However, nabiximols has better evidence than nabilone does -If considering medical cannabinoids, we recommend against medical marijuana (particularly smoked) as the initial product (strong recommendation (...) Herbal cannabis and pharmaceutical cannabinoid treatment following motor vehicle accidents: A state of the science review Herbal cannabis and pharmaceutical cannabinoid treatment following motor vehicle accidents: A state of the science review Final Report Carolyn J Green, PhD Ken L Bassett, MD, PhD Therapeutics Initiative University of British Columbia October 2018 Table of Contents 1.0 Developing a funding policy framework for ICBC insurance claims 1 1.1 Scientific medical knowledge
). Potency trends of ?9-THC and other cannabinoids in confiscated marijuana from 1980–1997. Journal of Forensic Sciences, 45(1), 24–30. Exley, C., Begum, A., Woolley, M. P ., & Bloor, R. N. (2006). Aluminum in tobacco and cannabis and smoking- related disease. American Journal of Medicine, 119(3), 276.e9–276.e11. Gargani, Y., Bishop, P ., & Denning, D. W. (2011). Too many mouldy joints—marijuana and chronic pulmonary aspergillosis. Mediterranean Journal of Hematology and Infectious Diseases, 3(1 (...) Canada. (2015). Statement on Supreme Court of Canada decision in R. v. Smith. Retrieved January 11, 2016, from www.hc-sc.gc.ca/ dhp-mps/marihuana/info/licencedproducer- producteurautorise/decision-r-v-smith-eng.php. Clearing the Smoke on Cannabis: Respiratory Effects of Cannabis Smoking Kempker, J. A., Honig, E. G., & Martin, G. S. (2015). The effects of marijuana exposure on expiratory airflow. A study of adults who participated in the U.S. National Health and Nutrition Examination Study. Annals