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Latest & greatest articles for calcium
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WHO recommendation on Calcium supplementation before pregnancy for the prevention of pre-eclampsia and its complications WHO recommendation on Calcium supplementation before pregnancy for the prevention of pre-eclampsia and its complicationsWHO recommendation on Calcium supplementation before pregnancy for the prevention of pre-eclampsia and its complicationsWHO recommendation on calcium supplementation before pregnancy for the prevention of pre-eclampsia and its complications ISBN 978-92-4 (...) . The original English edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization. Suggested citation. WHO recommendation on calcium supplementation before pregnancy for the prevention of pre-eclampsia and its complications. Geneva: World Health Organization; 2020. Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data. CIP data
Autologous Bone Graft Versus Silicate-Substituted Calcium Phosphate in the Treatment of Tunnel Defects in 2-Stage Revision Anterior Cruciate Ligament Reconstruction: A Prospective, Randomized Controlled Study With a Minimum Follow-up of 2 Years Autologous Bone Graft Versus Silicate-Substituted Calcium Phosphate in the Treatment of Tunnel Defects in 2-Stage Revision Anterior Cruciate Ligament Reconstruction: A Prospective, Randomized Controlled Study With a Minimum Follow-up of 2 Years - PubMed (...) ? Saved Search Alert Radio Buttons Yes No Email: ( ) Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Arthroscopy Actions . 2020 Jan;36(1):178-185. doi: 10.1016/j.arthro.2019.07.035. Autologous Bone Graft Versus Silicate-Substituted Calcium Phosphate in the Treatment of Tunnel Defects
Do Calcium Antagonists Decrease Mortality or Dependency in Acute Ischemic Stroke? Do Calcium Antagonists Decrease Mortality or Dependency in Acute Ischemic Stroke? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 74, Issue 4, Pages 575–577 Do Calcium Antagonists Decrease Mortality or Dependency in Acute Ischemic Stroke? x Rachel E. Bridwell , MD (EBEM Commentator) , x Brit Long , MD (EBEM Commentator (...) ) , x Michael D. April , MD, DPhil (EBEM Commentator) Department of Emergency Medicine, San Antonio Uniformed Services Health Education Consortium, Fort Sam Houston, TX DOI: | Publication History Published online: May 09, 2019 Expand all Collapse all Article Outline Take-Home Message The use of calcium antagonists in acute ischemic stroke does not reduce mortality or dependency in activities of daily living. Methods Data Sources An information specialist searched the Cochrane Stroke Group Trials
Calcium supplementation commencing before or early in pregnancy, for preventing hypertensive disorders of pregnancy. The hypertensive disorders of pregnancy include pre-eclampsia, gestational hypertension, chronic hypertension, and undefined hypertension. Pre-eclampsia is considerably more prevalent in low-income than in high-income countries. One possible explanation for this discrepancy is dietary differences, particularly calcium deficiency. Calcium supplementation in the second half (...) of pregnancy reduces the serious consequences of pre-eclampsia, but has limited effect on the overall risk of pre-eclampsia. It is important to establish whether calcium supplementation before, and in early pregnancy (before 20 weeks' gestation) has added benefit. Such evidence could count towards justification of population-level interventions to improve dietary calcium intake, including fortification of staple foods with calcium, especially in contexts where dietary calcium intake is known
Calcium, vitamin D or recombinant parathyroid hormone for managing post-thyroidectomy hypoparathyroidism. Post-surgical hypoparathyroidism is a common complication after thyroid surgery. The incidence is likely to increase given the rising trend in the annual number of thyroid operations being performed. Measures to prevent post-thyroidectomy hypoparathyroidism including different surgical techniques and prophylactic calcium and vitamin D supplements have been extensively studied (...) . The management of post-thyroidectomy hypoparathyroidism however has not been extensively evaluated. Routine use of calcium and vitamin D supplements in the postoperative period may reduce the risk of symptoms, temporary hypocalcaemia and hospital stay. However, this may lead to overtreatment and has no effect on long-term hypoparathyroidism. Current recommendations on the management of post-thyroidectomy hypoparathyroidism is based on low-quality evidence. Existing guidelines do not often distinguish between
Effect of Calcium-Channel Blocker Therapy on Radial Artery Grafts After Coronary Bypass Surgery Few studies have evaluated the effect of chronic calcium-channel blocker therapy (CCB) on the angiographic and clinical outcome of radial artery (RA) grafts used for coronary bypass surgery.The purpose of this study was to evaluate if CCB influences midterm clinical and angiographic outcomes of RA grafts.Patient-level data of 6 angiographic randomized trials evaluating RA graft status at midterm
Triple Antibiotic Solution Promotes Similar Antibacterial Effects as Calcium Hydroxide/2% Chlorhexidine When Used as an Intracanal Medicament UTCAT3361, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Triple Antibiotic Solution Promotes Similar Antibacterial Effects as Calcium Hydroxide/2% Chlorhexidine When Used as an Intracanal Medicament Clinical Question In patients undergoing non-surgical therapy in a tooth (...) diagnosed with pulpal necrosis, does the use of triple antibiotic paste as an intracanal medicament have better antibacterial efficacy than a calcium hydroxide/chlorhexidine formulation? Clinical Bottom Line Triple antibiotic solution (1 mg/mL) promoted similar antibacterial effects as calcium hydroxide/2% chlorhexidine when used as an intracanal medicament. This is based on several randomized clinical trials in which intracanal medicaments were placed for 7 to 21 days in primary and immature/mature
Astronaut Cardiovascular Health and Risk Modification (Astro-CHARM) Coronary Calcium Atherosclerotic Cardiovascular Disease Risk Calculator Coronary artery calcium (CAC) is a powerful novel risk indicator for atherosclerotic cardiovascular disease (ASCVD). Currently, there is no available ASCVD risk prediction tool that integrates traditional risk factors and CAC.To develop a CAC ASCVD risk tool for younger individuals in the general population, subjects aged 40 to 65 without prior
Is Adenosine or an Intravenous Calcium Channel Blocker More Effective for Treating Supraventricular Tachycardia? (SRS therapy) TAKE-HOME MESSAGE Among patients presenting with supraventricular tachycardia, rates of reversion to sinus rhythm and hypotension were similar between patients who were given adenosine or calcium channel blockers. Is Adenosine or an Intravenous Calcium Channel Blocker More Effective for Treating Supraventricular Tachycardia? EBEM Commentators Michael Gottlieb, MD (...) studies, although one study had both a verapamil and a diltiazem treat- ment arm. There was no difference in the rates of reversion to sinus rhythm between adenosine and calcium channel antagonists (Table). Three trials reported on hypotension, with only one case identi?ed in the calcium channel antagonist group. Four studies, comprising 442 patients, evaluated time to reversion, with a signi?cantly reduced time in the adenosine group (mean¼44 seconds) compared with the calcium channel antago- nist
Calcium Top results for calcium - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for calcium The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you
Patiromer sorbitex calcium (Veltassa) - for the treatment of hyperkalaemia in adults 1 patiromer (as patiromer sorbitex calcium) 8.4g and 16.8g powder for oral suspension (Veltassa ® ) SMC2084 Vifor Fresenius Medical Care Renal Pharma UK Ltd 6 July 2018 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHS Scotland. The advice is summarised as follows: ADVICE: following
Empagliflozin, calcium, and SGLT1/2 receptor affinity: another piece of the puzzle 30024112 2018 11 14 2018 11 14 2055-5822 5 4 2018 08 ESC heart failure ESC Heart Fail Empagliflozin, calcium, and SGLT1/2 receptor affinity: another piece of the puzzle. 549-551 10.1002/ehf2.12345 Anker Stefan D SD Division of Cardiology and Metabolism, Department of Cardiology (CVK), Berlin-Brandenburg Center for Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin (...) , Charité Universitätsmedizin Berlin, Berlin, Germany. Department of Cardiology and Pneumology, University Medicine Göttingen (UMG), Göttingen, Germany. Butler Javed J Department of Medicine, University of Mississippi, Jackson, MS, USA. eng Editorial Comment 2018 07 19 England ESC Heart Fail 101669191 2055-5822 0 Benzhydryl Compounds 0 Glucosides 0 Sodium-Glucose Transporter 1 HDC1R2M35U empagliflozin IY9XDZ35W2 Glucose SY7Q814VUP Calcium IM ESC Heart Fail. 2018 Aug;5(4):642-648 30117720 Benzhydryl
Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia. Beta thalassaemia is a common inherited blood disorder. The need for frequent blood transfusions in this condition poses a difficult problem to healthcare systems. The most common cause of morbidity and mortality is cardiac dysfunction from iron overload. The use of iron chelation therapy has reduced the severity of systemic iron overload but specific, non-toxic (...) treatment is required for removal of iron from the myocardium.To assess the effects of calcium channel blockers combined with standard iron chelation therapy in people with transfusion-dependent beta thalassaemia on the amount of iron deposited in the myocardium, on parameters of heart function, and on the incidence of severe heart failure or arrhythmias and related morbidity and mortality.We searched the Cochrane Haemoglobinopathies Trials Register, compiled from electronic database searches
Calcium-RasGRP2-Rap1 signaling mediates CD38-induced migration of chronic lymphocytic leukemia cells CD38 is a transmembrane exoenzyme that is associated with poor prognosis in chronic lymphocytic leukemia (CLL). High CD38 levels in CLL cells are linked to increased cell migration, but the molecular basis is unknown. CD38 produces nicotinic acid adenine dinucleotide phosphate and adenosine 5'-diphosphate-ribose, both of which can act to increase intracellular Ca2+ levels. Here we show that CD38
Heparin Oligosaccharides Have Antiarrhythmic Effect by Accelerating the Sodium-Calcium Exchanger Background: Blockage of the Na+/Ca2+ exchanger (NCX) is used to determine the role of NCX in arrhythmogenesis. Trisulfated heparin disaccharide (TD) and Low Molecular Weight Heparins (LMWHs) can directly interact with the NCX and accelerate its activity. Objective: In this work, we investigated the antiarrhythmic effect of heparin oligosaccharides related to the NCX activity. Methods: The effects (...) of heparin oligosaccharides were tested on the NCX current (patch clamping) and intracellular calcium transient in rat cardiomyocytes. The effects of heparin oligosaccharides were further investigated in arrhythmia induced in isolated rat atria and rats in vivo. Results: The intracellular Ca2+ concentration decreases upon treatment with either enoxaparin or ardeparin. These drugs abolished arrhythmia induction in isolated atria. The NCX antagonist KB-R7943 abolished the enoxaparin or ardeparin
Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: US Preventive Services Task Force Recommendation Statement. Because of the aging population, osteoporotic fractures are an increasingly important cause of morbidity and mortality in the United States. Approximately 2 million osteoporotic fractures occurred in the United States in 2005, and annual incidence is projected to increase to more than 3 million fractures by 2025. Within (...) 1 year of experiencing a hip fracture, many patients are unable to walk independently, more than half require assistance with activities of daily living, and 20% to 30% of patients will die.To update the 2013 US Preventive Services Task Force (USPSTF) recommendation on vitamin D supplementation, with or without calcium, to prevent fractures.The USPSTF reviewed the evidence on vitamin D, calcium, and combined supplementation for the primary prevention of fractures in community-dwelling adults
Calcium and vitamin D supplementation and increased risk of serrated polyps: results from a randomised clinical trial Serrated lesions such as sessile serrated adenomas or polyps (SSA/Ps) are important colorectal cancer precursors, but aetiological factors for these lesions are largely unknown. We aimed to determine the effects of calcium and vitamin D supplementation on the incidence of serrated polyps (SPs) in general and hyperplastic polyps and SSA/Ps specifically.Participants with one (...) or more adenoma at baseline were randomised to receive 1200 mg/day of elemental calcium, 1000 IU/day of vitamin D3, both or neither agent. Treatment continued for 3 or 5 years, when risk of polyps was determined from surveillance colonoscopy (treatment phase). Outcomes after treatment ceased were also assessed (observational phase). Adjusted risk ratios (aRRs) of SPs were determined via multivariable generalised linear models.SPs were diagnosed in 565 of 2058 (27.5%) participants during the treatment
Changes With Lanthanum Carbonate, Calcium Acetate, and Phosphorus Restriction in CKD: AÂ Randomized Controlled Trial Abnormal phosphorus homeostasis develops early in chronic kidney disease (CKD). It is unclear if its correction results in improved clinical outcomes in non-dialysis dependent CKD.We conducted a randomized controlled, parallel design clinical trial in 120 patients with estimated glomerular filtration rate 15 to 59 ml/min per 1.73 m2 and abnormal phosphorus homeostasis (serum (...) phosphorus >4.6 mg/dl, parathyroid hormone [PTH] >70 pg/ml or tubular reabsorption of phosphorus [TRP] <80%). Patients were randomized to open-label lanthanum carbonate versus calcium acetate versus dietary intervention over 1 year. The co-primary outcomes were month 12 (vs. baseline) biochemical (serum phosphorus, TRP, PTH, calcium, bone-specific alkaline phosphatase [bALP], and fibroblast growth factor 23 [FGF23]) and vascular parameters (coronary artery calcium score, pulse wave velocity
Evaluation of calcium and magnesium contents in tooth enamel without any pathological changes: in vitro preliminary study Enamel is the structure that covers the entire clinical crown of a tooth. It enables to chew and crush food, and gives a final shape to the crowns of teeth. To evaluate calcium and magnesium contents in tooth enamel and analyse relationships between the study minerals extracted human permanent teeth were cut at every 150 microns and subjected into acid biopsy. The amounts (...) of calcium and magnesium were assessed in the laboratory using atomic absorption spectroscopy with an air/acetylene flame. The lowest calcium and magnesium contents were found on the enamel surface of the teeth. Statistically significant correlation between the calcium and magnesium concentrations was found at a depth between 150 and 900 µm. Calcium and magnesium contents increased with increasing enamel depth. Calcium and magnesium deposits appeared to be stable through all the enamel layers studied
An assessment of neuronal calcium sensor-1 and response to neoadjuvant chemotherapy in breast cancer patients Neuronal calcium sensor-1 (NCS-1) has been identified as a binding partner of the taxane, paclitaxel. Our previous study showed that overexpression of NCS-1 increased the efficacy of paclitaxel in vitro, but was associated with poor clinical outcome. Here, we determine if NCS-1 expression is associated with pathological complete response (pCR) to taxane-based neoadjuvant chemotherapy