Feasibility of Ultra-Rapid Exome Sequencing in Critically Ill Infants and Children With Suspected Monogenic Conditions in the Australian Public Health Care System. Widespread adoption of rapid genomic testing in pediatric critical care requires robust clinical and laboratory pathways that provide equitable and consistent service across health care systems.To prospectively evaluate the performance of a multicenter network for ultra-rapid genomic diagnosis in a public health care

Effect of Intraoperative Dexamethasone on Major Complications and Mortality Among Infants Undergoing Cardiac Surgery: The DECISION Randomized Clinical Trial. Corticosteroids are widely used in pediatric cardiac surgery to blunt systemic inflammatory response and to reduce complications; nevertheless, their clinical efficacy is uncertain.To determine whether intraoperative administration of dexamethasone is more effective than placebo for reducing major complications and mortality during (...) pediatric cardiac surgery.The Intraoperative Dexamethasone in Pediatric Cardiac Surgery was an investigator-initiated, double-blind, multicenter randomized trial that involved 4 centers in China, Brazil, and Russia. A total of 394 infants younger than 12 months, undergoing cardiac surgery with cardiopulmonary bypass were enrolled from December 2015 to October 2018, with follow-up completed in November 2018.The dexamethasone group (n = 194) received 1 mg/kg of dexamethasone; the control group (n = 200

to breastfeed directly Encourage proper washing of hands and breasts with soap and water prior to handling the infant and advise the mother to wear a mask while nursing. Holding the baby skin-to-skin helps with latching and hormonal responses that trigger milk release. When not nursing, the infant can be cared for by a healthy caregiver, if available, and/or maintained in a separate room or at least six feet away from the mother. Once the mother is virologically cleared, these precautions can (...) calorie content of her milk. The expressed milk can be fed to the infant by a healthy caregiver. Support should be provided to the mother to reintroduce direct breastfeeding when she is well. Mother’s milk supply is established in the first few weeks postpartum, so this is a critical time to support milk production. Families should be reassured that mothers’ milk is safe and important for baby. Mother chose not to breastfeed during the first weeks after birth During the first week post-partum

droplet transmission. Don gown and gloves and use either an N95 respiratory mask and eye protection goggles or an air-purifying respirator that provides eye protection, for care of infants requiring supplemental oxygen at a flow >2 LPM, continuous positive airway pressure, or mechanical ventilation. Q: Should I test babies to determine if they are infected with SARS-CoV-2? A: If testing capacity is available, testing well newborns will facilitate plans for care after hospital discharge; will determine (...) Management of Infants Born to Mothers with Suspected or Confirmed COVID-19 FAQs: Management of Infants Born to Mothers with Suspected or Confirmed COVID-19 Internet Explorer Alert It appears you are using Internet Explorer as your web browser. Please note, Internet Explorer is no longer up-to-date and can cause problems in how this website functions This site functions best using the latest versions of any of the following browsers: Edge, Firefox, Chrome, Opera, or Safari . You can find

Health Intelligence Network produce these resources for commissioners and other health professionals to help them improve services. For further guidance and information about the tools and analysis please email . Older information from the network is available on . Published 14 June 2017 Last updated 12 March 2019 12 March 2019 Added information on the 'Pregnancy and early life: reducing stillbirth and infant death' planning tool. 31 January 2018 Added child development outcomes at 2 to 2 and a half (...) Child and maternal health data and intelligence: guide for health professionals Child and maternal health data and intelligence: guide for health professionals - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Child and maternal health data and intelligence: guide for health professionals Information to help healthcare professionals make decisions about the planning and provision of services using child

providers (e.g. GP, child health services, health workers) of discharge and follow-up actions required No Yes After care COVID-19 test • Not routinely recommended • Test if other clinical indications identified (e.g. becomes unwell) • Collect nasopharangeal and oropharangeal swab using a single swab for both sites Assess • If required care can be safely provided while baby co-located with mother Risk minimisation • Advise mother about importance of risk minimisation strategies • Restrict visitors (...) Maternity care for mothers and babies during the COVID-19 pandemic Maternity and Neonatal C linical G uideline Queensland Health Clinical Excellence Queensland Maternity care for mothers and babies during the COVID-19 pandemic (V2 draft v0.01) Queensland Clinical Guideline: Maternity care for mothers and babies during the COVID-19 pandemic Refer to online version, destroy printed copies after use Page 2 of 29 Document title: Maternity care for mothers and babies during COVID-19 pandemic

care research. www.acfp.ca June 1, 2020 “Does baby know best?”: Benefits and harms of baby-led weaning for transitioning to solid foods Clinical Question: What impact does baby-led weaning have on infant growth, iron intake, and choking? Bottom Line: Transitioning infants to solid foods using a baby-led weaning approach (with parental education) results in up to 0.7kg less weight gain at 12 months than traditional spoon feeding. This is of unknown clinical significance. There is no difference (...) ? Limitations: Open-label study, intervention group had 8 additional educational contacts, written materials, cook-books, and complementary packets of iron-fortified cereal. 2 • RCT not included in above systematic review, 280 children, 5-6 months of age. 9 After 12 months: o World Health Organization child growth standards: ? Baby-led weaning: 98% normal weight, 2% "underweight" (2 standard deviations below the mean). ? Spoon Feeding: 87% normal weight, 13% "overweight" (more than 1 standard deviation

Covid-19: Child Neurology Child neurology provision during the COVID-19 pandemic - eanpages COVID-19 May 13, 2020 COVID-19 May 13, 2020 COVID-19 May 6, 2020 COVID-19 May 6, 2020 COVID-19 May 13, 2020 COVID-19 May 13, 2020 COVID-19 May 6, 2020 COVID-19 May 6, 2020 Executive Page May 1, 2020 Executive Page April 1, 2020 Executive Page March 1, 2020 Executive Page February 1, 2020 Country of the Month May 1, 2020 Country of the Month April 5, 2020 Country of the Month March 1, 2020 Country (...) January 3, 2020 Patients societies reports January 2, 2020 Surveys April 10, 2020 Surveys October 7, 2019 Forum April 1, 2016 Forum March 1, 2016 Forum March 1, 2016 Forum February 1, 2016 Uncategorized May 2, 2020 Uncategorized May 1, 2020 Uncategorized May 1, 2020 Uncategorized April 29, 2020 Child neurology provision during the COVID-19 pandemic April 15, 2020 April 10, 2020 The number of subjects infected with SARS-Cov-2 is dramatically increasing worldwide since the beginning of this year

Care of the Well Child-Newly Diagnosed with Type 1 Diabetes Version 4, Dec 2019 Review 2022 Authors: J Chizo Agwu, SM Ng, A Timmis, C Moudiotis, K. Matyka,, N.P.Wright, M. Kershaw S.Bahl, A. Alston . N Trevelyan Page of 7 1 ssociation of Children’s Diabetes Clinicians Clinical Guideline Care of the well child, newly diagnosed with Type 1 Diabetes Mellitus SETTING Insert hospital name FOR STAFF Medical and nursing staff PATIENTS Children with diabetes and their families (...) , indicating an intensive regimen at baseline. Over time, A1c levels increased significantly in all groups, but A1c levels were significantly lower in the more-intensive group than in the no-change group at the 1-year and 2-year visits (p 5 mmol/L for driving o The ideal target blood glucose for each child may vary with age and stage of puberty. The aim is to achieve blood glucose levels as close to normal as possible whilst avoiding frequent or severe hypoglycaemia. Version 4, Dec 2019 Review 2022 Authors

Antenatal Hydronephrosis-Infant New 2020 ACR Appropriateness Criteria ® 1 Antenatal Hydronephrosis–Infant American College of Radiology ACR Appropriateness Criteria ® Antenatal Hydronephrosis–Infant Variant 1: Antenatal diagnosis of hydronephrosis. Initial neonatal imaging. Procedure Appropriateness Category Relative Radiation Level US kidneys and bladder Usually Appropriate O Voiding urosonography Usually Not Appropriate O Fluoroscopy voiding cystourethrography Usually Not Appropriate ?? MRI (...) Not Appropriate ?? ACR Appropriateness Criteria ® 2 Antenatal Hydronephrosis–Infant Variant 3: Antenatal diagnosis of hydronephrosis with isolated mild (SFU grade 1 and 2 or APRPD less than 15 mm) hydronephrosis on initial neonatal ultrasound. Procedure Appropriateness Category Relative Radiation Level US kidneys and bladder follow-up in 1-6 months Usually Appropriate O Voiding urosonography May Be Appropriate O Fluoroscopy voiding cystourethrography May Be Appropriate ?? MRI abdomen and pelvis with IV

examination and then go on to a UGI series varies greatly with the clinical and US practice of a given institution [43]. US is the first study of choice when there is a strong clinical suspicion of HPS. UGI series is an appropriate first study in infants with an atypical presentation for HPS or when the exam will be performed at a center with limited experience with US evaluation of the pylorus. Summary of Recommendations ? In imaging a child with bilious vomiting with possible malrotation, a UGI series (...) . Hilton S. The child vomiting. In: Hilton S, Edwards D, eds. Practical Pediatric Radiology. Philadelphia, Pa.: BC Decker; 1994:297-299. 3. Ryan S, Donoghue V. Gastrointestinal pathology in neonates: new imaging strategies. Pediatr Radiol. 2010;40(6):927-931. 4. Hernanz-Schulman M. Imaging of neonatal gastrointestinal obstruction. Radiol Clin North Am. 1999;37(6):1163-1186, vi-vii. 5. Lilien LD, Srinivasan G, Pyati SP, Yeh TF, Pildes RS. Green vomiting in the first 72 hours in normal infants. Am J Dis

with seizures. J Child Neurol. 2009;24(9):1105-1111. 12. Krishnamoorthy KS, Soman TB, Takeoka M, Schaefer PW. Diffusion-weighted imaging in neonatal cerebral infarction: clinical utility and follow-up. J Child Neurol. 2000;15(9):592-602. 13. Hsieh DT, Chang T, Tsuchida TN, et al. New-onset afebrile seizures in infants: role of neuroimaging. Neurology. 2010;74(2):150-156. 14. Hesdorffer DC, Chan S, Tian H, et al. Are MRI-detected brain abnormalities associated with febrile seizure type? Epilepsia. 2008;49(5 (...) Seizures-Child Date of origin: 1995 Last review date: 2012 ACR Appropriateness Criteria ® 1 Seizures — Child American College of Radiology ACR Appropriateness Criteria ® Clinical Condition: Seizures — Child Variant 1: Neonatal seizures. Radiologic Procedure Rating Comments RRL* US head 9 O MRI head without IV contrast 5 Particularly for hypoxic ischemic encephalopathy (HIE) and congenital malformations. O MRI head without and with IV contrast 4 O CT head without IV contrast 3 ??? CT head

of outborn transport of an infant born to a COVID-positive mother. Air or ground transport personnel are in very close quarters, and the baby’s condition may be evolving. Guidance must balance the likelihood of true infection with the risk of transmission, which can be influenced by the infant’s age (whether newborn or days old), duration of transport, symptomatology, and airway support. The earliest documented COVID-19 positive test result for a newborn was at 36 hours of age [ ] . Given this, when (...) NICU care for infants born to mothers with suspected or proven COVID-19 NICU care for infants born to mothers with suspected or proven COVID-19NICU care for infants born to mothers with suspected or proven COVID-19 | Canadian Paediatric Society A home for paediatricians. A voice for children and youth. Current: NICU care for infants… Practice Point NICU care for infants born to mothers with suspected or proven COVID-19 Posted: Apr 6 2020 The Canadian Paediatric Society gives permission to print

the outcomes of 10 infants, including 6 preterm infants, born to COVID-19 positive mothers [ ] . Although respiratory illness was common in this cohort, all infants were pharyngeal-swab negative. This illustrates that when attending a high-risk delivery, COVID-related neonatal respiratory distress is highly unlikely. Illness should not be inappropriately attributed to COVID-19 without appropriate consideration for more common entities. Attendance at delivery for babies of COVID-positive mothers (...) Delivery room considerations for infants born to mothers with suspected or proven COVID-19 Delivery room considerations for infants born to mothers with suspected or proven COVID-19Delivery room considerations for infants born to mothers with suspected or proven COVID-19 | Canadian Paediatric Society A home for paediatricians. A voice for children and youth. Current: Delivery room… Practice Point Delivery room considerations for infants born to mothers with suspected or proven COVID-19 Posted

in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Int J Nurs Stud Actions . 2020 Apr;104:103532. doi: 10.1016/j.ijnurstu.2020.103532. Epub 2020 Jan 24. The Effect of Expressed Breast Milk, Swaddling and Facilitated Tucking Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants: A Randomized Controlled Trial , Affiliations Expand Affiliations 1 Child Health Nursing Department (...) , Faculty of Health Sciences, Gumuşhane University, Gümüşhane 29000, Turkey. 2 Child Health Nursing Department, Nursing Faculty, Akdeniz University, Antalya 07058, Turkey. Electronic address: eefe@akdeniz.edu.tr. PMID: 32062050 DOI: Item in Clipboard The Effect of Expressed Breast Milk, Swaddling and Facilitated Tucking Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants: A Randomized Controlled Trial Vildan Apaydin Cirik et al. Int J Nurs Stud . 2020 Apr . Show details

Pulmonary surfactant for respiratory distress syndrome in premature infants 1 Driving better decision-making in healthcare Pulmonary surfactant for treating respiratory distress syndrome in premature infants Technology Guidance from the MOH Drug Advisory Committee Published on 1 April 2020 Guidance recommendations The Ministry of Health’s Drug Advisory Committee has recommended: ? Calfactant 105 mg/3 ml and 210 mg/6 ml intratracheal suspension vials for treating respiratory distress syndrome (...) in premature infants. Subsidy status Calfactant 105 mg/3 ml and 210 mg/6 ml intratracheal suspension vials are recommended for inclusion on the MOH Standard Drug List (SDL) for the abovementioned indication. SDL does not apply to beractant 200 mg/8 ml vial and poractant alfa 120 mg/1.5 ml vial. 2 Driving better decision-making in healthcare Factors considered to inform the recommendations for subsidy Technology evaluation 1.1 1.2 1.3 The MOH Drug Advisory Committee (“the Committee”) considered the evidence

COVID-19 - Isolation plans for parent-child combinations COVID-19 - Isolation plans for parent-child combinations | RCPCH Quick links Quick links Search RCPCH Search X Search RCPCH Search Submenu membership Submenu education Submenu work we do Submenu resources Submenu key topics Submenu news and events Quick links Quick links Submenu membership Submenu education Submenu work we do Submenu resources Submenu key topics Submenu news and events X COVID-19 - Isolation plans for parent-child (...) combinations This page has a single parent and child meeting COVID-19 case definition - isolation plan while waiting for virology results. Last modified 8 April 2020 Post date 8 April 2020 Child Parent Management Well* Well* Child – home isolation Parent – home isolation Well* Level 1 Child – home isolation – support from social care Parent – adult ward ** Well* Level 2/3 Child – home isolation – support from social care. Parent – adult ward ** Escalate to HDU/ITU as per usual pathway Level 1 Well* Child

Nutritional evaluation of the neurologically impaired child Nutrition is of key importance in optimizing function and health in children with neurological impairment (NI). Challenges in quantifying individual needs and assessing nutritional status are barriers to determining the nutritional prescription. This practice point addresses common questions faced by clinicians caring for this population and uses available evidence to provide strategies to address these challenges. Keywords

Renamed 2015 References 1. Murphy BP, Inder TE, Rooks V, et al. Posthaemorrhagic ventricu- lar dilatation in the premature infant: natural history and predictors of outcome. Arch Dis Child Fetal Neonatal Ed 2002; 87:F37–F41. 2. Rosenberg HK, Viswanathan V, Amodio J. Pediatric brain. In: McGahan JP, Goldberg BB (eds). Diagnostic Ultrasound. Vol 1. 2nd ed. New York, NY: Informa Healthcare; 2008:563–612. 3. Rumack CM, Levine D. Neonatal and infant brain imaging. In: Diagnostic Ultrasound. Vol 2. 5th ed (...) , Sanchez-Zaplana H, Ruiz JC, Jimenez-Cobo B. Rupture of intracranial arterial aneurysms in neonates: case report and review of the literature. J Child Neurol 2009; 24:208–214. 10. Wang HS, Kuo MF, Chang TC. Sonographic lenticulostriate vasculopathy in infants: some associations and a hypothesis. AJNR Am J Neuroradiol 1995; 16:97–102. 11. de Vries LS, Cowan FM. Evolving understanding of hypoxic- ischemic encephalopathy in the term infant. Semin Pediatr Neurol 2009; 16:216–225. 12. Govaert P. Prenatal

Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial. Skin emollients applied during early infancy could prevent atopic dermatitis, and early complementary food introduction might reduce food allergy in high-risk infants. The study aimed to determine if either regular skin emollients applied from 2 weeks of age, or early complementary feeding introduced between 12 and 16 weeks of age, reduced (...) development of atopic dermatitis by age 12 months in the general infant population.This population-based 2×2 factorial, randomised clinical trial was done at Oslo University Hospital and Østfold Hospital Trust, Oslo, Norway; and Karolinska University Hospital, Stockholm, Sweden. Infants of women recruited antenatally at the routine ultrasound pregnancy screening at 18 weeks were cluster-randomised at birth from 2015 to 2017 to the following groups: (1) controls with no specific advice on skin care while