Latest & greatest articles for autism

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This page lists the very latest high quality evidence on autism and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Autism

Autism is a neurodevelopmental disorder (a type of mental disorder) characterised by difficult social interaction, impaired communication (both verbal and non-verbal), and restricted and repetitive behaviours. It forms part of the broader autism spectrum disorder (ASD), a range of similar conditions, including Asperger syndrome.

Autism is a condition that begins from early childhood and is often suspected and diagnosed by ages 1-3. It is a lifelong disability that affects how people interact with others.

Autism causes and treatment

There have been many misconceptions as to what causes autism in the past such as the MMR vaccine and diet. Extensive research and clinical trials have concluded that none of these factors cause autism or ASD. However, the real cause is little understood but research is starting to unpick potential factors such as genetics, pollution and other environmental factors. A current favoured idea is that genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors.

The exact cause of autism spectrum disorder is unknown, however research into the disorder suggest that it is caused by several genetic and environmental factors. Genes inherited from a child’s parents can make them more vulnerable to developing autism, some researchers suggest that the disorder will only develop when triggered by environmental factors. Read more in clinical papers on autism.

Autism can be managed with a combination of prescribed medicines and behavioural treatment, depending on the severity of the disorder. Read about clinical trials and medical advancements for the treatment of autism on Trip.

Hot topics in Trip

Users of Trip frequently look at topics around adolescents, therapies, behaviour and screening. They also explore such topics as omega-3 fatty acids, SSRIs and aripiprazole. All these topics, and more, can be easily searched for within Trip.

Top results for autism

1. Maternal Influenza A(H1N1) Immunization During Pregnancy and Risk for Autism Spectrum Disorder in Offspring : A Cohort Study. (Abstract)

Maternal Influenza A(H1N1) Immunization During Pregnancy and Risk for Autism Spectrum Disorder in Offspring : A Cohort Study. There are concerns that influenza vaccine exposure during pregnancy may be associated with increased risk for autism spectrum disorder (ASD).To examine the risk for ASD in offspring of mothers who were vaccinated against influenza A(H1N1)pdm09 ("swine flu") during pregnancy.Population-based cohort study using nationwide registers.Seven health care regions in Sweden.Live (...) births between October 2009 and September 2010, with follow-up through December 2016. In total, 39 726 infants were prenatally exposed to H1N1 vaccine (13 845 during the first trimester) and 29 293 infants were unexposed.Cox regression was used to estimate hazard ratios (HRs) for the primary outcome, ASD, before and after adjustment for potential confounders. The secondary outcome was autistic disorder (AD).Mean follow-up was 6.7 years in both unexposed and exposed children. During follow-up, 394

2020 Annals of Internal Medicine

2. Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder

Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder A Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other (...) citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation J Pediatr Actions . 2020 Jul;222:164-173.e5. doi: 10.1016/j.jpeds.2020.03.011. Epub 2020 May 19. A Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder

2020 EvidenceUpdates

3. Implementation of Advanced Methods for Reproductive Pharmacovigilance in Autism: A Meta-Analysis of the Effects of Prenatal Antidepressant Exposure

, Rickert ME, Öberg AS, Quinn PD, Hernández-Díaz S, Almqvist C, Lichtenstein P, Larsson H, D'Onofrio BM. Sujan AC, et al. JAMA. 2017 Apr 18;317(15):1553-1562. doi: 10.1001/jama.2017.3413. JAMA. 2017. PMID: 28418479 Free PMC article. Show more similar articles Publication types Meta-Analysis Actions MeSH terms Antidepressive Agents / therapeutic use* Actions Autism Spectrum Disorder / epidemiology Actions Autistic Disorder / epidemiology* Actions Control Groups* Actions Depressive Disorder / drug therapy (...) Implementation of Advanced Methods for Reproductive Pharmacovigilance in Autism: A Meta-Analysis of the Effects of Prenatal Antidepressant Exposure Implementation of Advanced Methods for Reproductive Pharmacovigilance in Autism: A Meta-Analysis of the Effects of Prenatal Antidepressant Exposure - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily

2020 EvidenceUpdates

4. Interventions based on early intensive applied behaviour analysis for autistic children: a systematic review and cost-effectiveness analysis Full Text available with Trip Pro

Interventions based on early intensive applied behaviour analysis for autistic children: a systematic review and cost-effectiveness analysis Interventions based on early intensive applied behaviour analysis for autistic children: a systematic review and cost-effectiveness analysis Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from (...) the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} This review found limited evidence that early intensive applied behaviour analysis-based interventions improve cognitive ability and adaptive behaviour in autistic children, but the long-term impact of the interventions remains unknown. {{author}} {{($index , , , , , , , , & . Mark Rodgers 1 , David Marshall 1 , Mark Simmonds 1

2020 NIHR HTA programme

5. Measles-mumps-rubella vaccine (MMR): no link with autism

FEATURED REVIEW Studies based on a very significant number of children, taken together, do not show any link between MMR vaccination and the occurrence of autistic disorders. The authors of the two studies claiming the opposite used incorrect data or applied inappropriate analytical methods. Full review (3 pages) available for download by subscribers. Abstract Studies proposing a link between the measles-mumps-rubella vaccine (MMR) and autism were published in 1998 and 2014, and then retracted because (...) Measles-mumps-rubella vaccine (MMR): no link with autism Prescrire IN ENGLISH - Spotlight ''Measles-mumps-rubella vaccine (MMR): no link with autism'', 1 May 2020 {1} {1} {1} | | > > > Measles-mumps-rubella vaccine (MMR): no link with autism Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Measles-mumps-rubella vaccine (MMR): no link with autism

2020 Prescrire

6. Interventions for anxiety in mainstream school-aged children with autism spectrum disorder (ASD) Full Text available with Trip Pro

, diagnosed with ASD (inclusive of autism, ASD, Autistic Disorder, Asperger's Disorder, Asperger Syndrome, atypical autism, PDD‐NOS) by a professional eligible to diagnose these conditions, and also experiencing anxiety symptoms or a diagnosis of an anxiety disorder provided by a professional eligible to diagnose such conditions. The majority of included studies (21 of 24) used a screening instrument to confirm the existence of clinically significant levels of anxiety at intake, while the remaining (...) excluded at abstract screening stage Author and Publication Date Title Reason for exclusion Schohl et al. ( ) A replication and extension of the PEERS intervention: Examining effects on social skills and social anxiety in adolescents with autism spectrum disorders. Different intervention focus, no anxiety diagnosis or measurement at intake Ooi et al. ( ) Effects of cognitive‐behavioral therapy on anxiety for children with high‐functioning autistic spectrum disorders. Observational study (pre‐post

2020 Campbell Collaboration

7. Cognitive Behavioral Treatments for Anxiety in Children With Autism Spectrum Disorder: A Randomized Clinical Trial

Cognitive Behavioral Treatments for Anxiety in Children With Autism Spectrum Disorder: A Randomized Clinical Trial Cognitive Behavioral Treatments for Anxiety in Children With Autism Spectrum Disorder: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily unavailable (...) your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation JAMA Psychiatry Actions 2019 Nov 22 [Online ahead of print] Cognitive Behavioral Treatments for Anxiety in Children With Autism Spectrum Disorder: A Randomized Clinical Trial , , , , , , , Affiliations Expand Affiliations 1 Department of Education, University of California, Los Angeles, Los Angeles. 2 Department

2020 EvidenceUpdates

8. Provision for people with a known or suspected learning disability, autism or both

Provision for people with a known or suspected learning disability, autism or both NHS England » Provision for people with a known or suspected learning disability, autism or both Search Search Menu Provision for people with a known or suspected learning disability, autism or both Document first published: 22 January 2020 Page updated: 22 January 2020 Topic: Publication type: Document PDF 432 KB 22 pages

2020 NHS England

9. Treatment for Insomnia and Disrupted Sleep Behavior in Children and Adolescents with Autism Spectrum Disorder

Treatment for Insomnia and Disrupted Sleep Behavior in Children and Adolescents with Autism Spectrum Disorder 1 1 Practice guideline: Treatment for insomnia and disrupted sleep behavior in children and 2 adolescents with autism spectrum disorder 3 4 Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the 5 American Academy of Neurology 6 7 Ashura Williams Buckley, MD, 1 Deborah Hirtz, MD, 2 Maryam Oskoui, MD, 3 Melissa J. 8 Armstrong, MD, MSc, 4 Anshu Batra (...) . Division of Developmental Medicine, Boston Children’s Hospital, Boston, MA 24 2 7. Departments of Pediatrics and Psychiatry, The Ohio State University College of 1 Medicine, Columbus 2 8. Duke Center for Autism and Brain Development, Duke Institute for Brain Sciences, and 3 Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 4 Durham, NC 5 9. Northern Michigan Neurology, Traverse City 6 10. Department of Child and Behavioral Sciences, Johns Hopkins University

2020 American Academy of Neurology

10. Association of Comorbid Mood and Anxiety Disorders With Autism Spectrum Disorder (Abstract)

Association of Comorbid Mood and Anxiety Disorders With Autism Spectrum Disorder It is critical to evaluate the risk of comorbid psychiatric diagnoses to meet the needs of individuals with autism spectrum disorder (ASD).To examine whether individuals with ASD are at greater risk for comorbid diagnoses of depression, anxiety, or bipolar disorder.This cohort study used data from a population-based birth cohort of 31 220 individuals born in Olmsted County, Minnesota, from January 1, 1976

2020 EvidenceUpdates

11. Effect of a Computer-Based Decision Support Intervention on Autism Spectrum Disorder Screening in Pediatric Primary Care Clinics: A Cluster Randomized Clinical Trial Full Text available with Trip Pro

Effect of a Computer-Based Decision Support Intervention on Autism Spectrum Disorder Screening in Pediatric Primary Care Clinics: A Cluster Randomized Clinical Trial Effect of a Computer-Based Decision Support Intervention on Autism Spectrum Disorder Screening in Pediatric Primary Care Clinics: A Cluster Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed (...) collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation JAMA Netw Open Actions , 2 (12), e1917676 2019 Dec 2 Effect of a Computer-Based Decision Support Intervention on Autism Spectrum Disorder Screening in Pediatric Primary Care Clinics: A Cluster Randomized Clinical

2020 EvidenceUpdates

12. Linking risk factors and outcomes in autism spectrum disorder: is there evidence for resilience? Full Text available with Trip Pro

Linking risk factors and outcomes in autism spectrum disorder: is there evidence for resilience? Autism spectrum disorder (referred to here as autism) is one of several overlapping neurodevelopmental conditions that have variable impacts on different individuals. This variability results from dynamic interactions between biological and non-biological risk factors, which result in increasing differentiation between individuals over time. Although this differentiation continues well (...) into adulthood, the infancy period is when the brain and behavior develop rapidly, and when the first signs and symptoms of autism emerge. This review discusses advances in our understanding of the causal pathways leading to autism and overlapping neurodevelopmental conditions. Research is also mapping trajectories of brain and behavioral development for some risk groups, namely later born siblings of children with autism and/or infants referred because of developmental concerns. This knowledge has been

2020 BMJ

13. Guided self-help for depression in autistic adults: the ADEPT feasibility RCT Full Text available with Trip Pro

Guided self-help for depression in autistic adults: the ADEPT feasibility RCT Guided self-help for depression in autistic adults: the ADEPT feasibility RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1 (...) )"> {{metadata.Title}} {{metadata.Headline}} This low-intensity psychological intervention was feasible and well-received, and a full trial is warranted. {{author}} {{($index , , , , , , , , , , & . Ailsa Russell 1, * , Daisy Gaunt 2 , Kate Cooper 1 , Jeremy Horwood 2 , Stephen Barton 3 , Ian Ensum 4 , Barry Ingham 5 , Jeremy Parr 6 , Chris Metcalfe 2 , Dheeraj Rai 7 , David Kessler 7 , Nicola Wiles 8 1 Centre for Applied Autism Research, Department of Psychology, Faculty of Humanities and Social Sciences

2020 NIHR HTA programme

14. Autism in adults: Scenario: Managing confirmed autism

be available for people with ASD and how to decisions about benefits; services; and other (such as blue badges, bus passes, and Disabled Facilities Grants). The National Autistic Society Autism Helpline (0808 800 4104, ) — provides impartial, confidential information, advice, and support for people with ASD and their family, partners, and/or carers. It is available from 10am–4pm on Monday–Thursday, and 9am–3pm on Fridays. The NHS website ( ) — has a guide on , which is also available in an for people (...) pain. Coexisting mental health disorders, for example anxiety, depression, or schizophrenia. See the CKS topics on , , and for management information. Communication problems with difficulty in understanding situations or expressing needs and wishes. Visual aids (such as words, pictures, or symbols) can be used to aid communication. The National Autistic Society website ( ) has information on for people with autism spectrum disorder (ASD). Changes to routine or personal circumstances. Offer

2020 NICE Clinical Knowledge Summaries

15. Autism in children

Autism in children Autism in children | Topics A to Z | CKS | NICE Search CKS… Menu Autism in children Autism in children Last revised in October 2018 Autism spectrum disorder (ASD) is a lifelong condition,which significantly limits or impairs the activities of daily life Diagnosis Management Background information Autism in children: Summary Autism spectrum disorder (ASD) is a complex developmental condition that includes a range of developmental impairments in reciprocal social interaction (...) or young person and their family and/or carers. The diagnosis of ASD is established by a specialist following referral. Ideally this is carried out by an autism team if available (or if not, by a paediatrician or a child and adolescent psychiatrist [dependant on local referral policy]). Primary care management of children and young people with confirmed ASD generally includes: Routine review, where appropriate. Ensuring those with ASD and an associated mental health or behavioural disorder are reviewed

2020 NICE Clinical Knowledge Summaries

16. Autism in children: Scenario: How should I manage a child or young person with suspected autism spectrum disorder?

Autism in children: Scenario: How should I manage a child or young person with suspected autism spectrum disorder? Scenario: Managing suspected autism | Management | Autism in children | CKS | NICE Search CKS… Menu Scenario: Managing suspected autism Autism in children: Scenario: How should I manage a child or young person with suspected autism spectrum disorder? Last revised in October 2018 Scenario: How should I manage a child or young person with suspected autism spectrum disorder? From (...) birth to 19 years. How should I manage a child or young person with suspected autism spectrum disorder? Arrange immediate referral to an autism team if available (or if not, to a paediatrician or a child and adolescent psychiatrist [dependant on local referral policy]): If there is a high probability of autism spectrum disorder (ASD) due to the following features: In children under 3 years of age — regression of language or social developmental milestones. In children or young people of any age

2020 NICE Clinical Knowledge Summaries

17. Autism in adults: Scenario: Managing suspected autism

: The National Autistic Society website ( ) has information on available before diagnosis of ASD, the , , available , and what to do . Basis for recommendation These recommendations are based largely on the National Institute for Health and Care Excellence (NICE) guidelines Autism. Recognition, referral, diagnosis and management of adults on the autism spectrum (full NICE guideline) [ ] and Autism spectrum disorder in adults: diagnosis and management [ ]. For detailed information on the evidence NICE used (...) Autism in adults: Scenario: Managing suspected autism Scenario: Managing suspected autism | Management | Autism in adults | CKS | NICE Search CKS… Menu Scenario: Managing suspected autism Autism in adults: Scenario: Managing suspected autism Last revised in June 2019 Scenario: Managing suspected autism From age 18 years onwards. How should I manage an adult with suspected autism spectrum disorder? For adults with autism spectrum disorder (ASD) who do not have a moderate or severe learning

2020 NICE Clinical Knowledge Summaries

18. Covid-19: Management of patients with a learning disability, autism or both

Covid-19: Management of patients with a learning disability, autism or both Publications approval reference: 001559 NHS England and NHS Improvement Speciality guides for patient management during the coronavirus pandemic Clinical guide for front line staff to support the management of patients with a learning disability, autism or both during the coronavirus pandemic – relevant to all clinical specialities 24 March 2020 Version 1 “…and there are no more surgeons, urologists, orthopaedists, we (...) response in hospitals. We may also need to work outside our specific areas of training and expertise and the General Medical Council (GMC) has already indicated its support for this in the exceptional circumstances we may face: www.gmc-uk.org/news/news-archive/how-we-will-continue-to-regulate-in-light-of- novel-coronavirus As a clinician working in other fields you may have had limited clinical contact with people with a learning disability or people with autism, however in 2018/19 at least 41

2020 Covid-19 Ad hoc guidelines

19. Early detection for autism spectrum disorder in young children

Early detection for autism spectrum disorder in young children Autism spectrum disorder (ASD) is a life-long neurodevelopmental disorder, characterized by impairments in social communication, repetitive, restricted patterns of behaviour, and unusual sensory sensitivities or interests. ASD significantly impacts the lives of children and their families. Currently, the estimated prevalence of ASD is 1 in 66 Canadians aged 5 to 17 years. General paediatricians, family physicians, and other health (...) signs of ASD—an important step toward an accurate diagnosis and comprehensive needs assessment for intervention planning. Keywords: Autism spectrum disorder; Developmental surveillance; Early identification; Screening

2019 Canadian Paediatric Society

20. Post-diagnostic management and follow-up care for autism spectrum disorder

Post-diagnostic management and follow-up care for autism spectrum disorder Paediatricians and other primary care providers are well positioned to provide or coordinate ongoing medical and psychosocial care and support services for children with autism spectrum disorder (ASD). This statement provides recommendations and information on a range of interventions and resources, to help paediatric care providers optimize care for children with ASD and support their families. The management of ASD (...) includes treating medical and psychiatric co-morbidities, behavioural and developmental interventions, and providing supportive social care services to enhance quality of life for affected children and families. Keywords: Autism spectrum disorder; Behavioural interventions; Complementary and alternative medicine; Developmental interventions; Pharmacological management

2019 Canadian Paediatric Society