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Latest & greatest articles for screening
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on screening or other clinical topics then use Trip today.
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Practice Guide for Sickle Cell Trait Identified in Newborn Screening PRACTICE GUIDE FOR SICKLE CELL TRAIT IDENTIFIED IN NEWBORN SCREENING | April 2019 These recommendations are systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances. They should be used as an adjunct to sound clinical decision making. OBJECTIVE To provide guidance to health care providers when they receive notification a newborn (...) be implications for other family members. See Appendix B for frequently asked questions to help guide your discussions with the family. 1 Practice Guide for Sickle Cell Trait Identified in Newborn Screening | April 2019 Practice Guide Page 2 of 9 Implementation Considerations HEALTH EXPECTATIONS FOR PEOPLE WITH SICKLE CELL TRAIT Most people who carry SCT will not have associated health problems and they will not develop SCD. In rare cases, carriers may experience some health issues such as hematuria
Screening hysteroscopy in subfertile women and women undergoing assisted reproduction. Screening hysteroscopy in infertile women with unexplained infertility, or prior to intrauterine insemination (IUI) or in vitro fertilisation (IVF) may reveal intrauterine pathology that may not be detected by routine transvaginal ultrasound. Hysteroscopy, whether purely diagnostic or operative may improve reproductive outcomes.To assess the effectiveness and safety of screening hysteroscopy in subfertile (...) women undergoing evaluation for infertility, and subfertile women undergoing IUI or IVF.We searched the Cochrane Gynaecology and Fertility Group Specialised Register, CENTRAL CRSO, MEDLINE, Embase, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform (September 2018). We searched reference lists of relevant articles and handsearched relevant conference proceedings.Randomised controlled trials comparing screening hysteroscopy versus no intervention
Screening for Elevated Blood Lead Levels in Childhood and Pregnancy: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. Elevated blood lead level is associated with serious, often irreversible, health consequences.To synthesize evidence on the effects of screening, testing, and treatment for elevated blood lead level in pregnant women and children aged 5 years and younger in the primary care setting to inform the US Preventive Services Task Force.Cochrane (...) CENTRAL and Cochrane Database of Systematic Reviews (through June 2018) and Ovid MEDLINE (1946 to June 2018); surveillance through December 5, 2018.English-language trials and observational studies of screening for and treating elevated lead levels in asymptomatic children and pregnant women.Independent critical appraisal and data abstraction by 2 reviewers using predefined criteria.Elevated blood lead level, morbidity, mortality, clinical prediction tools, test accuracy, adverse events.A total of 24
Screening for Elevated Blood Lead Levels in Children and Pregnant Women: US Preventive Services Task Force Recommendation Statement. Elevated blood lead levels in children are associated with neurologic effects such as behavioral and learning problems, lower IQ, hyperactivity, hearing problems, and impaired growth. In pregnant women, lead exposure can impair organ systems such as the hematopoietic, hepatic, renal, and nervous systems, and increase the risk of preeclampsia and adverse perinatal (...) outcomes. Many of the adverse health effects of lead exposure are irreversible.To update the 2006 US Preventive Services Task Force (USPSTF) recommendation on screening for elevated blood lead levels in children and pregnant women.The USPSTF reviewed the evidence on the benefits and harms of screening for and treatment of elevated blood lead levels. In this update, an elevated blood lead level was defined according to the Centers for Disease Control and Prevention reference level of 5 μg/dL.The USPSTF
Prehospital stroke scales as screening tools for early identification of stroke and transient ischemic attack. Rapid and accurate detection of stroke by paramedics or other emergency clinicians at the time of first contact is crucial for timely initiation of appropriate treatment. Several stroke recognition scales have been developed to support the initial triage. However, their accuracy remains uncertain and there is no agreement which of the scales perform better.To systematically identify (...) and review the evidence pertaining to the test accuracy of validated stroke recognition scales, as used in a prehospital or emergency room (ER) setting to screen people suspected of having stroke.We searched CENTRAL, MEDLINE (Ovid), Embase (Ovid) and the Science Citation Index to 30 January 2018. We handsearched the reference lists of all included studies and other relevant publications and contacted experts in the field to identify additional studies or unpublished data.We included studies evaluating
Screening for Breast Cancer in Average-Risk Women: A Guidance Statement From the American College of Physicians. The purpose of this guidance statement is to provide advice to clinicians on breast cancer screening in average-risk women based on a review of existing guidelines and the evidence they include.This guidance statement is derived from an appraisal of selected guidelines from around the world that address breast cancer screening, as well as their included evidence. All national (...) is all clinicians, and the target patient population is all asymptomatic women with average risk for breast cancer.In average-risk women aged 40 to 49 years, clinicians should discuss whether to screen for breast cancer with mammography before age 50 years. Discussion should include the potential benefits and harms and a woman's preferences. The potential harms outweigh the benefits in most women aged 40 to 49 years.In average-risk women aged 50 to 74 years, clinicians should offer screening
Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis. To determine the accuracy of the Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression.Individual participant data meta-analysis.Medline, Medline In-Process and Other Non-Indexed Citations, PsycINFO, and Web of Science (January 2000-February 2015).Eligible studies compared PHQ-9 scores with major depression diagnoses from validated
Depression in primary care: part 1-screening and diagnosis. Depression is a common and heterogeneous condition with a chronic and recurrent natural course that is frequently seen in the primary care setting. Primary care providers play a central role in managing depression and concurrent physical comorbidities, and they face challenges in diagnosing and treating the condition. In this two part series, we review the evidence available to help to guide primary care providers and practices (...) to recognize and manage depression. In this first of two reviews, we outline an approach to screening and diagnosing depression in primary care that evaluates current evidence based guidelines and applies the recommendations to clinical practice. The second review presents an evidence based approach to the treatment of depression in primary care, detailing the recommended lifestyle, drug, and psychological interventions at the individual level. It also highlights strategies that are being adopted
Cervical screening and risk of adenosquamous and rare histological types of invasive cervical carcinoma: population based nested case-control study. To examine the association of cervical cytology screening with the risk of adenosquamous cell carcinoma (ASC) and rare histological types of invasive cervical carcinoma (RICC), using comprehensive registry data, and to assess tumour human papillomavirus status of ASC and RICC.Nationwide, population based, nested case-control study.Sweden.All cases (...) density sampling.Conditional logistic regression was used to calculate odds ratios, interpreted as incidence rate ratios, for risk of ASC and RICC in relation to screening status and screening history, adjusted for education. Human papillomavirus distribution of ASC and RICC was based on available archival tumour tissues from most Swedish pathology biobanks.Women with two screening tests in the previous two recommended screening intervals had a lower risk of ASC (incidence rate ratio 0.22, 95
Accuracy of Self-Report for Cervical and Breast Cancer Screening Management Briefs eBrief-no152 -- Accuracy of Self-Report for Cervical and Breast Cancer Screening Enter search terms Button to search HSRD ® Inside VA Budget and Performance Inside the News Room National Observances Special Events » » » » » Management Briefs eBrief-no152 -- Accuracy of Self-Report for Cervical and Breast Cancer Screening Health Services Research & Development Management eBrief no. 152 » Issue 152 April 2019 (...) The report is a product of the VA/HSR&D Evidence Synthesis Program. Evidence Brief: Accuracy of Self-Report for Cervical and Breast Cancer Screening Guideline-based breast and cervical cancer screening are considered essential health benefits and are fundamental components of high-quality primary care services in the United States. The aim of cancer screening is to identify cancers in an early stage when treatment is more likely to be effective. Accurate measurement of cancer screening rates is vital
Elevated Blood Lead Levels in Children and Pregnant Women: Screening Final Update Summary: Elevated Blood Lead Levels in Children and Pregnant Women: Screening - US Preventive Services Task Force Search USPSTF Website Text size: Assembly version: 22.214.171.1248 Last Build: 11/16/2018 6:27:19 PM You are here: Final Summary Elevated Blood Lead Levels in Children and Pregnant Women: Screening Release Date: April 2019 Recommendation Summary Population Recommendation Grade Children 5 years and younger (...) The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for elevated blood lead levels in asymptomatic children. Pregnant persons The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for elevated blood lead levels in asymptomatic pregnant persons. To read the recommendation statement in JAMA , select . To read the evidence summary in JAMA , select . See the for suggestions
Practice Advisory: Cell-free DNA to Screen for Single-Gene Disorders Practice Advisory: Cell-free DNA to Screen for Single-Gene Disorders - ACOG Menu ▼ Practice Advisory: Cell-free DNA to Screen for Single-Gene Disorders Page Navigation ▼ Share: Practice Advisory: Cell-free DNA to Screen for Single-Gene Disorders February 21, 2019 This is an area of evolving care and practice. Fellows should check periodically for revisions and updates. ACOG will communicate important changes and updates (...) to these guidelines. The continued innovation in cell-free technology combined with the desire for a maternal blood test to predict the risk for fetal genetic disorders during a pregnancy has broadened the application of cell-free DNA screening beyond aneuploidy to single-gene disorders. Examples of single-gene disorders include various skeletal dysplasias, sickle cell disease and cystic fibrosis. Although this technology is available clinically and marketed as a single-gene disorder prenatal screening option
Systematic screening and assessment of psychosocial well-being and care needs of people with cancer. Receiving a diagnosis of cancer and the subsequent related treatments can have a significant impact on an individual's physical and psychosocial well-being. To ensure that cancer care addresses all aspects of well-being, systematic screening for distress and supportive care needs is recommended. Appropriate screening could help support the integration of psychosocial approaches in daily routines (...) in order to achieve holistic cancer care and ensure that the specific care needs of people with cancer are met and that the organisation of such care is optimised.To examine the effectiveness and safety of screening of psychosocial well-being and care needs of people with cancer. To explore the intervention characteristics that contribute to the effectiveness of these screening interventions.We searched five electronic databases in January 2018: the Cochrane Central Register of Controlled Trials
Infographic: Disaster Triage Accuracy Following Screen-Based Simulation versus Immersive Simulation Infographic: Disaster Triage Accuracy Following Screen-Based Simulation versus Immersive Simulation - CanadiEM Infographic: Disaster Triage Accuracy Following Screen-Based Simulation versus Immersive Simulation In , by Anson Dinh March 15, 2019 In this issue, we collaborated with the INSPIRE (International Network for Simulation-based Pediatric Innovation, Research, & Education) team to create (...) an infographic on the article “Correlation Between Paramedic Disaster Triage Accuracy in Screen-Based Simulations and Immersive Simulations.” published by Cicero et al. 1 Screen-based simulation (SBS) is an emerging alternative to traditional teaching methods which require both learner and educator to be present. 2 SBS allows the learner freedom to learn at their own pace. This study investigated the impact of using SBS and automated feedback (demonstrated on the left side of the infographic). These results
Primary cervical screening with high risk human papillomavirus testing: observational study. To provide the first report on the main outcomes from the prevalence and incidence rounds of a large pilot of routine primary high risk human papillomavirus (hrHPV) testing in England, compared with contemporaneous primary liquid based cytology screening.Observational study.The English Cervical Screening Programme.578 547 women undergoing cervical screening in primary care between May 2013 and December (...) 2014, with follow-up until May 2017; 183 970 (32%) were screened with hrHPV testing.Routine cervical screening with hrHPV testing with liquid based cytology triage and two early recalls for women who were hrHPV positive and cytology negative, following the national screening age and interval recommendations.Frequency of referral for a colposcopy; adherence to early recall; and relative detection of cervical intraepithelial neoplasia grade 2 or worse from hrHPV testing compared with liquid based
Predictive performance of the competing risk model in screening for preeclampsia The established method of screening for preeclampsia is to identify risk factors from maternal demographic characteristics and medical history; in the presence of such factors the patient is classified as high risk and in their absence as low risk. However, the performance of such an approach is poor. We developed a competing risks model, which allows combination of maternal factors (age, weight, height, race (...) of the competing risks model in screening for preeclampsia by a combination of maternal factors, mean arterial pressure, uterine artery pulsatility index, and serum placental growth factor, referred to as the triple test, in a training data set for the development of the model and 2 validation studies.The data for this study were derived from 3 previously reported prospective, nonintervention, multicenter screening studies for preeclampsia in singleton pregnancies at 11+0 to 13+6 weeks' gestation. In all 3
Persisting new nodules in incidence rounds of the NELSON CT lung cancer screening study The US guidelines recommend low-dose CT (LDCT) lung cancer screening for high-risk individuals. New solid nodules after baseline screening are common and have a high lung cancer probability. Currently, no evidence exists concerning the risk stratification of non-resolving new solid nodules at first LDCT screening after initial detection.In the Dutch-Belgian Randomized Lung Cancer Screening (NELSON) trial (...) , 7295 participants underwent the second and 6922 participants the third screening round. We included participants with solid nodules that were registered as new or <15 mm³ (study detection limit) at previous screens and received additional screening after initial detection, thereby excluding high-risk nodules according to the NELSON management protocol (nodules ≥500 mm3).Overall, 680 participants with 1020 low-risk and intermediate-risk new solid nodules were included. A total of 562 (55%) new solid
Testing behavioral interventions to optimize participation in a population-based colorectal cancer screening program in Catalonia, Spain The aim of the study was to measure the effect of three cost-neutral behavioral interventions on participation compared to the standard invitation letter in a population-based colorectal cancer screening program in 2014. For that purpose, a four-arm randomized field trial was conducted among 5077 individuals aged 50 to 69 years. Over an 8-week period, each (...) week was randomly allocated to the intervention or the control conditions. Individuals assigned to the intervention conditions additionally received a prompt to write down the date to pick up the screening test in a pharmacy. Two of the three intervention groups also included an additional paragraph in the invitation letter on either: 1) the high proportion of individuals participating regularly (social norms condition) or 2) the importance of regular participation (benefit condition). We measured
New screening pathway could help to identify a rare, single-gene form of diabetes New screening pathway could help to identify a rare, single-gene form of diabetes Discover Portal Discover Portal New screening pathway could help to identify a rare, single-gene form of diabetes Published on 23 January 2018 doi: A screening pathway using blood and urine tests followed by two genetic (DNA) tests identified all people with a rare subtype of diabetes called monogenic diabetes. The screening pathway (...) study looked at whether a three-step screening process could better identify who should be referred for DNA testing. What did this study do? The UNITED study included 1,418 people in two UK regions diagnosed with diabetes before the age of 30 and currently aged under 50. There were 42 known cases of monogenic diabetes in the sample (previously diagnosed by DNA test). The researchers tested everyone eligible using a three-step diagnostic pathway which included DNA tests for everyone. Firstly